Stem cell studies always catch my eye. This very small study involves people treated with their own bone marrow, which was collected and expanded to give it the ability to modulate the MS immune response before being reinjected into their spinal canal. But despite what the headline says, the results only showed a two-year benefit for some of the patients. People who showed the most benefit were those with the lowest disability level at the start of the study.
There are a lot of facts and figures to consider, so be sure to read the entire story, not just my brief summary, to understand what’s happening here.
Lesser or stable disability over two years was evident in most progressive multiple sclerosis (MS) patients given a stem cell treatment in a small Phase 1 clinical trial, supporting a larger study now underway, researchers report.
These results suggest that a treatment using mesenchymal stem cell-derived neural progenitors (MSC-NPs) can safely and effectively ease inflammation in progressive MS.
Click here to read the full story.
It’s not unusual for an MS diagnosis to take a long time, sometimes several years. These researchers are considering whether it’s possible to use a particular protein as an indicator of whether a patient has MS. That might shorten the time to a diagnosis.
They also think that increasing the amount of this protein might delay the onset of MS, ease its symptoms, and delay progression. The protein would do this by blocking some rogue immune cells from entering the central nervous system, while also helping to boost the number of immune cells that repair the immune system. Wouldn’t that all be nice?
However, so far, it’s only been studied in mice.
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