MS News That Caught My Eye Last Week: Stem Cell Trial, COVID-19 Vaccines, MS Blood Test

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by Ed Tobias |

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First Patient Dosed in Phase 1 Trial of IMS001 Therapy

IMS001 is an investigational treatment that uses mesenchymal stem cells (MSC) — cells derived from human embryos. Preclinical studies have shown that IMS001 has the ability to stabilize an overactive immune system, as is the case in people with MS, as well as repair the blood-brain barrier. These researchers believe IMS001 has the potential to reduce symptom relapses and disease progression, and encourage disease arrest.

ImStem Biotechnology announced that the first patient in its Phase 1 clinical trial for IMS001, an investigational treatment for multiple sclerosis (MS), has been dosed at the Shepherd Center in Atlanta.

The trial (NCT04956744) is recruiting participants with an MS diagnosis ages 18 to 65. More information is available on this link.

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COVID-19 Vaccine Side Effects With MS Similar to Public at Large

This information is based on a self-reporting survey of 719 people with MS. I was one of them. My side effects, after each of my Moderna shots, were minimal, the same as reported by most of the people in this group.

Side effects upon receiving the COVID-19 vaccine in people with multiple sclerosis (MS) are similar to those reported in the general population, and patients on certain disease-modifying therapies are less likely to have vaccine reactions, a survey-based study found.

The findings provide “a reassuring picture” for those who feel hesitant about vaccination or are yet to be vaccinated. Further research on the immune response to vaccination is underway, according to a press release from the National MS Society, which funded the work.

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Mynd Tests MAP, Blood Biomarker for MS Diagnosis

One of the things missing from the group of procedures used to diagnose MS is a simple blood test. Perhaps not much longer. Clinical research could begin in a few months on such a test, and its developer hopes to seek U.S. Food and Drug Administration approval for it as soon as the second half of next year.

Mynd Diagnostics is launching a clinical study to test the ability of a blood biomarker, which the company coined Mynd anti-inflammatory peptide (MAP), to help in the diagnosis and monitoring of multiple sclerosis (MS).

Starting in the first quarter of 2022, the company will collect blood samples from diagnosed patients to compare their biomarker levels against control samples.

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Note: Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those of Multiple Sclerosis News Today or its parent company, BioNews, and are intended to spark discussion about issues pertaining to multiple sclerosis.

Comments

Lisa Carr avatar

Lisa Carr

I’m not seeing an article on SCT?

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Ed Tobias avatar

Ed Tobias

Hi Lisa,

It's the first story, about IMS001 treatment.

Ed

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Lisa Carr avatar

Lisa Carr

Hi ed, i found it and wrote them! Thx

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