Columns The MS Wire - A Column by Ed Tobias MS News Notes: Climate Change, MS Progression, Brain Shrinkage MS News Notes: Climate Change, MS Progression, Brain Shrinkage Columnist Ed Tobias comments on the week's top MS news by Ed Tobias | November 28, 2022 Share this article: Share article via email Copy article link Welcome to āMS News Notes,ā where I comment on multiple sclerosis (MS) news stories that caught my eye last week. Hereās a look at whatās happening: Study reports climate change makes MS symptoms worse Climate change may lead to more perils than rising oceans, harsher storms, and melting ice caps. It can also have a direct impact on people with MS and other illnesses. In the MS News Today articleĀ “Climate Change Risk to MS Patients: Worse Symptoms, More Relapses,” Lindsey Shapiro reports on a review of 364 studies into temperature, disease, and pollution changes from the past 32 years. The result: “Temperature fluctuations and extreme weather events were associated with changes in a number of neurological conditions, includingĀ symptoms for MS patients,” Shapiro writes. Poorer air quality, also a result of climate change, was associated with an increased risk of an MS relapse. Recommended Reading November 25, 2022 Columns by Ed Tobias Dr. Amazon Takes a Third Jab at Medical Care Slowing progression and reducing relapses with a supplement Neuroaspis plp10 is a dietary supplement that contains a combination of polyunsaturated fatty acids (PUFAs) and several antioxidants, namely vitamin E and gamma-tocopherol. PUFAs can be found in fish and nuts. In a proof-of-concept trial reported by MS News Today’s Marisa Wexler in “Add-on Supplement May Bolster Interferon Therapies for RRMS,” researchers say adding this supplement to some existing treatments helped reduce relapses and slow MS progression. An experimental therapy hopes to halt MS progression Vidofludimus calcium is a small molecule that interferes with the normal metabolism of T-cells and B-cells, which are immune cells that drive inflammation in MS. This experimental treatment works by inhibiting an enzyme that is essential for these cellsā proliferation, making them eventually die. The MS News Today article “2 Years of Vidofludimus Calcium Thwarts Disability Progression: Data” reports that only a few patients treated with continuous vidofludimus calcium for two years developed confirmed disability worsening. Those whose disability did worsen were on the lower end of what would be expected with approved MS medications. If you want to know how to talk to a patient, talk to a patient What’s the best way for a neurologist to speak with a patient about the brain shrinkage that’s a part of MS? A team of doctors and researchers who wanted to know the answer to that question did something pretty unique in medical research ā they asked some patients. In meetings and workshops that spanned two years, the medical people put their heads together with 26 people who live with MS. They came up with about a dozen recommendations, which you can read about in Marisa Wexler’s MS News Today article “MS Patients Help Steer Guidelines for Talks About Brain Volume Loss.” Note:Ā Multiple Sclerosis News TodayĀ is strictly a news and information website about the disease. It does not provide medical advice,Ā diagnosis, orĀ treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those ofĀ Multiple Sclerosis News TodayĀ or its parent company, BioNews, and are intended to spark discussion about issues pertaining to multiple sclerosis. Print This Page About the Author Ed Tobias People say to write what you know and Ed Tobias knows about MS. He's lived with the illness since 1980, when he was 32 years old. Ed's a retired, award-winning broadcast journalist and his column combines his four decades of MS experiences with news and comments about the latest in the MS community. In addition to writing his column, Ed is one of the patient moderators on the MS News Today Facebook, Twitter, and Instagram sites. Heās also the author of āThe Multiple Sclerosis Toolbox: Hints and Tips for Living with M.S.ā Ed and his wife split their time between the Washington, D.C. suburbs and Floridaās Gulf Coast, trying to follow the sun. Tags MS News Comments Kathryn Pasquini MR. Tobias, How will you know when your brain is shrinking? Thanks, Kathryn Pasquini Reply Ed Tobias Hi Kathryn, Brain atrophy can be seen on an MRI. Take a look at my answer to Chastity Stanfield about this with a link to more info. Ed Reply chasity Stanfield Ive had MS since 2011 I had no idea about brain shrinkage? Reply Ed Tobias Hi Chasity, I'm sorry you weren't told about this when you were diagnosed. Brain atrophy, or shrinkage, is one of the reasons many neurologists think it best to start a disease-modifying therapy soon after diagnosis, rather than waiting for more obvious, physical symptoms to appear. As my neurologist puts it "time is brain." Here's some more info for you: http://multiplesclerosisnewstoday.com/news-posts/2022/05/25/relapsing-ms-silent-progression-show-similar-brain-volume-loss-rate/ Ed Reply Kelly Burke I was diagnosed with RRMS is 1988. I am currently on Ocrevus (for 2 years). MRI's show white matter is fairly stable ( I have multiple lesions/plaque in my brain and spinal cord). The":gray matter" is a different story. Brain shrinkage for the last 2 years. Frontal lobe problems - starting cognition issues for this past year. I don't seem to have much support from my neurologist on finding possible alternative medine to add which might be helpful. My mother has vascular dementia and watching her decline is scaring me. I know I don't have Vascular dementia.......but......I have a lot of the cognitive problems and others. I am not sure what my question is. :-) I do read your column and MS Today. thank you, Kelly Burke Reply Ed Tobias Hi Kelly, Thanks for being one of my readers. Ocrevus is one of the disease-modifying treatments that's used to try to limit brain atrophy but there are others, such as Lemtrada. Still others are in the works. I'm not a healthcare professional so I can't suggest anything specifically but it might be worthwhile to ask of a switch of DMTs might help. Ed Reply Leave a comment Fill in the required fields to post. 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