Women with multiple sclerosis (MS) who have never given birth and those who began menopause prematurely tend to develop progressive forms of the disease earlier, a study from the Mayo Clinic suggests.
These findings were presented at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2020, running through Saturday, Feb. 29, in Florida.
Burcu Zeydan, MD, a Mayo Clinic physician, shared the results in the oral presentation “Nulliparity Or Early Menopause Are Associated With Earlier Evolution Of Progressive Multiple Sclerosis In Women.“
“Being a woman is the strongest risk factor for developing MS,” Zeydan said.
Gender also has an influence on the different stages of the disease. In those with relapsing-remitting MS (RRMS), women tend to have disease onset at earlier ages, while disability worsening is faster in men. The opposite is seen in the disease’s progressive phase, with men tending to have onset at earlier ages and women showing faster disability worsening.
Pregnancy is known to potentially slow disability worsening and reduce relapse rates in women, while menopause “potentially speeds up disability worsening,” Zeydan said.
However, the influence of pregnancy and menopause on progressive MS has not been thoroughly studied.
We are sorry that this post was not useful for you!
Let us improve this post!
Tell us how we can improve this post?