antigens

Repertoire Immune Medicines and Yale University have entered a research collaboration to identify what type of antigens are activating immune T-cells in patients with multiple sclerosis (MS). Antigens are molecular structures, such as a portion of a protein or a specific chain of sugars, that trigger an immune…

Red blood cells carrying specific antigen proteins on the cell surface can be used to disarm overactive T-cells by promoting immune tolerance, a study in mice found. The findings may have important implications for the treatment of autoimmune diseases like multiple sclerosis. The study, “Persistent antigen…

A new primate model uncovered by researchers can help scientists understand the immune and inflammatory processes underlying the development of multiple sclerosis (MS) in humans, a study reports. It was already known that Japanese macaques — also called snow monkeys — can spontaneously develop encephalomyelitis (JME), a disorder that…

Scientists at the UCLA Broad Stem Cell Research Center have developed a technique able to more efficiently isolate specific T-cells — immune cells involved not only in the fight against infections and cancer but also in autoimmune diseases such as multiple sclerosis (MS) — for research. In particular, the…

Secondary progressive multiple sclerosis (SPMS) patients have larger quantities of certain antibodies to the stomach ulcer bacterium Helicobacter pylori than those with relapsing-remitting multiple sclerosis (RMSS), finds a Greek study which also showed that MS patients in general differ from healthy people in this aspect. Although researchers at the University of Thessaly think…

Researchers managed to change the immune system — replacing inflammation with immune tolerance — in a mouse model of multiple sclerosis (MS) using so-called quantum dots, or nano-sized particles carrying pieces of myelin. Experiments with this advanced technological solution may help researchers design MS therapies that are based on promoting regulatory T-cells rather…

Researchers managed to retrain the immune system to ignore antigens that trigger an autoimmune reaction. This approach alleviated the symptoms of multiple sclerosis (MS) and type 1 diabetes in a mouse model.