January 13, 2017 News by Patricia Inacio, PhD B-cells Differ in Pediatric- and Adult-onset MS, Study Shows The immune system B-cells responsible for producing antibodies are different in those who developĀ multiple sclerosis (MS) asĀ children,Ā than in those who developĀ it as adults, a study shows. The research, āB-cell populations discriminate between pediatric- and adult-onset multiple sclerosis,ā was published in the journalĀ Neurology: Neuroimmunology & NeuroInflammation. Because only 3…
July 13, 2016 News by Patricia Inacio, PhD Steroid Use Lowers Oxidative Stress in Cerebrospinal Fluid of Progressive MS Patients in Pilot Study AĀ pilot study inĀ patients with progressive multiple sclerosis (MS) found a steroid treatmentĀ of benefit by decreasingĀ oxidative stressĀ in theĀ cerebrospinal fluid. The study, āOne-time intrathecal triamcinolone acetonide application alters the redox potential in cerebrospinal fluid of progressive multiple sclerosis patients: a pilot study,ā was published in the journalĀ …
June 24, 2016 News by Patricia Silva, PhD Micro-RNA Levels May Be Diagnostic Marker, Distinguishing MS from Other Neurological Diseases Patients with multiple sclerosis (MS) have higher levels of a micro-RNA called miR-150 in their cerebrospinal fluid, a liquid surrounding and protectingĀ the brain and spinal cord. The study, validating the finding in someĀ 600 people, suggests that miR-150 might be a marker for MS, distinguishing the disease from other neurological conditions.
March 23, 2016 News by Patricia Silva, PhD High Lactate Levels in MS Patients Tied to Disease Progression, Mitochondrial Dysfunction Scientists in recent years have wonderedĀ whether a link exists betweenĀ high lactate levels resulting from mitochondrial dysfunction andĀ multiple sclerosis (MS) progression. Now researchers in Italy showed that lactate, a metabolic byproduct, is indeed increased in the cerebrospinal fluid of MS patients andĀ may beĀ a disease driver. Mitochondria are the bodyās energy factories,…
February 1, 2016 News by Patricia Silva, PhD Protein Seen to Impede Remyelination in Multiple Sclerosis Patients Researchers from Karolinska Institute, Sweden, reported that the immune-associated protein lipocalin-2 (LCN2) is increased in multiple sclerosis, particularly inĀ patients with progressive MS. The researchers, however, concluded that the factor cannotĀ be used as a biomarker for the disease. The study, “Lipocalin-2 is increased in progressive multiple sclerosis…