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A man-made molecule derived from a naturally occurring amino acid was able to promote the repair of the myelin sheath — a fatty coating around nerve fibers that is damaged in multiple sclerosis — in a mouse model of the disease, a new study reports. “These findings suggest that ……

Blocking production of the low-density lipoprotein receptor-related protein 1 (LRP1) — involved in inflammatory and immune responses — specifically in myelin repair cells halts neuroinflammation and promotes myelin repair, a preclinical study shows. These results, from two mouse models of multiple sclerosis (MS), shed light on the underlying mechanisms…

Giving estrogen to two different adult mouse models of multiple sclerosis (MS), including the experimental autoimmune encephalomyelitis (EAE) model, promoted remyelination, a new study shows. Exposure to the hormone affected gene activity in oligodendrocytes, tricking them into producing myelin (the fatty substance that protects nerve cells, and that is destroyed…

Activation of the immune response mediated by cells called microglia favors remyelination and myelin repair in multiple sclerosis (MS), according to a new Canadian study using mice. The research, “mCSF-Induced Microglial Activation Prevents Myelin Loss and Promotes Its Repair in a Mouse Model of Multiple Sclerosis,” was…

People with multiple sclerosis (MS) are three to six times more likely to develop epilepsy than the general population, a study says. Researchers believe the loss of myelin in certain neurons — a hallmark of MS — is what causes the seizures. The study was published in the journal…

The National Institutes of Health (NIH) awarded a $45,000 grant to a team of investigators, led by Tia Walker, PhD, at Indiana University Northwest, to support a research project into the role of copper in multiple sclerosis (MS). The award is a first for IU Northwest, and will allow the team to…