Cholesterol made by neurons is crucial for repairing long-term damage to the myelin sheath, the fatty coating around nerve fibers that is damaged in multiple sclerosis (MS), according to a new report based on experiments done on mice. The finding suggests that increasing neuronal cholesterol synthesis may be helpful…

An interaction between immune cells and glia cells in the brain, mediated by the C1q complement system protein, appears to drive chronic inflammation in multiple sclerosis (MS), new research shows. Inhibiting this protein helped to resolve inflammation in mouse models of MS and in tissue cultures, its researchers found.

A new research project, funded by the National Institutes of Health (NIH), aims to better understand how different types of cells in the nervous system — specifically neurons and glia cells — communicate with each other and ultimately affect both motor and non-motor functions. Its findings may have important implications…

Researchers have identified a molecular switch that awakens stem cells in a specific region of the mouse brain — and with their activation, two new types of glia, non-neuronal cells that play critical roles in brain function, also were discovered. Notably, the development of these new glial cell types also…

Startup company Oscine Therapeutics has received an investment from Sana Biotechnology to support the research and development of cell-based therapies for a variety of neurological disorders, including multiple sclerosis (MS). This venture is based on work done over the past several decades in the lab of Steve…

A subset of stem cells in hair follicles, called melanocytes, appear to do more than just give rise to mature melanocytes, cells that help to determine hair color. Those melanocyte stem cells, or McSCs, that carry the CD34 protein were found in hair follicles from mice to differentiate into glia cells…