Anxiety and depression are associated with lower cognitive abilities in patients with multiple sclerosis (MS) other and immune-mediated inflammatory diseases such as inflammatory bowel disease (IBD) and rheumatoid arthritis, a study shows. These findings indicate the importance of managing symptoms of anxiety and depression in MS, as…
IBD
The use of antibiotics in childhood, which alters the microbiome — or natural bacteria flora in the gut — may increase the risk of multiple sclerosis (MS), inflammatory bowel disease (IBD) and other inflammatory diseases, according to an Australian study. The mouse study, “Early-life antibiotic treatment enhances the…
In a new study, researchers at UT Southwestern Medical Center in Texas and The Scripps Research Institute in California discovered that the enzyme NEK7, vital to cell division, plays a crucial role in the activation of the NLRP3 inflammasome, essential to the onset of inflammation. This discovery may have a significant impact…
Celgene to Acquire Receptos, Advancing Leadership in Immune-Inflammatory Diseases Such As MS and IBD
Summit, New Jersey based Celgene Corporation and Receptos, Inc. of San Diego, California, a biopharmaceutical company developing therapeutic candidates for the treatment of immune and metabolic diseases, have announced their joint signing of a definitive agreement in which Celgene will acquire Receptos. Under terms of the merger agreement,…
The Alliance for Children’s Therapeutics recently announced its plans to broaden its scope of research programs to include several diseases, namely, inflammatory bowel disease (IBD), asthma, and multiple sclerosis (MS) — a progressive, neurodegenerative disease that is estimated to affect 300,000…
A new study entitled “Intestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cells” published in September issue of PloS One, reports that disruption of intestinal homeostasis supports Experimental Autoimmune Encephalomyelitis, the prototypic…