lipids

High Lipid Levels Associated with Increased Disability, Inflammation in RRMS Patients, Study Shows

High levels of certain lipids, or fat, in the blood are linked to increased disability scores and high levels of pro-inflammatory markers inĀ relapsing-remitting multiple sclerosis (RRMS) patients, a small study reports. The study, ā€œLipoprotein markers associated with disability from multiple sclerosis,ā€ was published in the journal Scientific…

Instability of Myelin Membranes May Be True Trigger of MS, Study Reports

In multiple sclerosis (MS), scientists have long believed that the body’s own immune systemĀ attacked myelin sheaths,Ā the “insulating tape” that surrounds neurons, causingĀ the disease. But researchers at Tel Aviv University are challenging that view, inĀ a study reporting that MS may in fact be triggeredĀ byĀ an instability inherent in the myelin membranes. The…

MS Study Finds Lipid Antibodies Reflect Changes in Brain Volume and Lesions

Brigham and Womenā€™s HospitalĀ researchers reported that antibodies directed at lipids are associated with magnetic resonance imaging (MRI) measures of brain degenerationĀ in patients with multiple sclerosis (MS), and may potentially serve asĀ biomarkers for monitoring disease status. While the hyperintense brain lesions detected by MRI are crucial for diagnosis and therapeutic…

Potential MS Therapeutic Targets Found in Plasma Metabolites

In a new study entitled ā€œUntargeted plasma metabolomics identifies endogenous metabolite with drug-like properties in chronic animal model of multiple sclerosis,ā€ a team of researchers performed a comparative analysis of metabolites between control mice and a mouse model with experimental autoimmune encephalitis (EAE, the most commonly used…