April 5, 2024 News by InĆŖs Martins, PhD Nykode’s ‘inverse vaccine’ found to prevent MS in mouse model An inverse vaccine developed by Nykode Therapeutics to boost immune system tolerance to a specific protein target was able to prevent the development of multiple sclerosis (MS) in a mouse model of the disease. The vaccine, known as a Vaccibody, is designed to teach the immune system to…
January 11, 2024 News by Marisa Wexler, MS MS patients have high levels of T-cells targeting EBV-infected B-cells People with multiple sclerosis (MS) have high levels of T-cells in their spinal fluid that specifically target cells infected with the Epstein-Barr virus (EBV), according to a new study. These T-cells were found in samples collected from patients during their diagnostic workup in the early stages of…
January 11, 2024 News by Lindsey Shapiro, PhD Depression in pregnancy linked to autoimmune disease, especially MS Women with a history of depression around the time they get pregnant are at increased risk of developing autoimmune diseases such as multiple sclerosis (MS), according to recent research. Likewise, women who have an autoimmune disease are more likely to get depressed during pregnancy and in the year after…
January 3, 2024 News by Patricia Inacio, PhD People living with HIV significantly less likely to develop MS: Study Living with the human immunodeficiency virus (HIV) is linked to a significantly lower rate of developing multiple sclerosis (MS) ā including among people exposed to antiretroviral treatment, or medicines that can stop the HIV virus from replicating ā a new study found. The rate of MS was particularly reduced…
May 19, 2023 News by Marisa Wexler, MS New study data may help explain EBV and MS link When the immune system launches an attack to fight off infection with the Epstein-Barr virus, immune cells can accidentally end up targeting a protein called CRYAB that’s normally expressed by healthy myelin-making cells in the brain, a study found. The findings provide further evidence that molecular similarities between distinct…
September 15, 2022 News by Vanda Pinto, PhD H. Pylori Infection May Increase MS Risk But More Studies Are Needed Infection with the stomach bacterium Helicobacter pylori (H. pylori) does not appear to protect against the development of multiple sclerosis (MS), a review study has found. However, when researchers focused on studies that used microscopic assessments of tissue instead of other diagnostic methods to detect H. pylori, their data…
May 4, 2021 News by Margarida Maia, PhD Repertoire, Yale Working to Identify T-cells Driving MS Repertoire Immune Medicines and Yale University have entered a research collaboration to identify what type of antigens are activating immune T-cells in patients withĀ multiple sclerosis (MS). Antigens are molecular structures, such as a portion of a protein or a specific chain of sugars, that trigger an immune…