MS Patients at Higher Risk of Bladder Cancer, But Not Breast, Colorectal Cancer
People with multiple sclerosis (MS) are at a higher risk of developing and dying from bladder cancer than people…
Articles by Marta Figueiredo, PhD
Novartis, iHeartRadio Partner to Launch 1st Streaming Station for MS Community
Novartis has partnered with iHeartRadio to launch the first free on-demand streaming radio station dedicated to the…
Gut Immune Cells That Travel to Brain May Help Resolve MS Disease Relapses
A particular type of gut microbiota-reactive immune cells, called IgA-producing B-cells, travels to the brain of multiple…
Early Use of Ocrevus Best for Slowing PPMS Progression, Long-term Data Show
Early and continuous use of Ocrevus (ocrelizumab) significantly slows disability progression and delays the time until wheelchair reliance in people with…
Smartphone Typing Patterns May Be Tool for Monitoring MS Progression, Study Finds
Typing patterns in daily smartphone use show clinically relevant changes over time in people with multiple sclerosis (MS), but…
MS Patients With Depression Symptoms Have More Difficulty Multitasking, Study Shows
Patients in the early stages of multiple sclerosis with mild to moderate symptoms of depression performed worse on cognitive…
Autoimmune Registry Releases Comprehensive US List of These Diseases
The nonprofit Autoimmune Registry (ARI) has published its first comprehensive list of autoimmune diseases, with information addressing more than…
TEPP-46 Might Worsen MS Rather Than Treat It, Study Suggests
Using a small molecule called TEPP-46 to block the non-metabolic function of the enzyme pyruvate kinase M2 (PKM2) in…
Additional Group of RRMS Patients Sought to Take Lower Dose of IMU-838 in Phase 2 Trial
Immunic Therapeutics is seeking 60 more adults with relapsing-remitting multiple sclerosis (RRMS) to test a lower dose of IMU-838,…
Stem Cell Transplant More Effective Than Lemtrada in Treating RRMS, Study Suggests
An autologous hematopoietic stem cell transplant (AHSCT) is more effective than Lemtrada (alemtuzumab) at achieving no evidence of disease activity…
Ocrevus Still Reigns for Progressive MS, Spherix Reports, But Challenges Noted
Genentech’s Ocrevus (ocrelizumab) continues to be the most prescribed treatment for people with progressive forms of multiple sclerosis (MS)…
Adults With MS Wanted for 12-week Trial Assessing Health Benefits of Tele-exercise
Adults with multiple sclerosis (MS) and other neurological disorders are being recruited to take part in a 12-week clinical…
MD1003 Fails to Prevent Disability Progression in Progressive MS Patients, Trial Shows
MD1003, MedDay Pharmaceuticals’ high-dose biotin therapy, failed to significantly improve functional ability or walking speed in people…
Metabolic Enzyme PKM2 a Potential Therapeutic Target for MS, Preclinical Study Suggests
Suppressing pyruvate kinase M2 (PKM2) — an enzyme involved in cellular metabolism — in T-helper (Th) immune cells lessened myelin…
Biogen Discontinues Development of Opicinumab for MS
Biogen is discontinuing the clinical development of opicinumab, its experimental treatment candidate for multiple sclerosis (MS), based on data from the…
New Genetic Variants Found in African Americans of European Ancestry at Higher MS Risk
Two genetic variants have been identified by researchers within a genome region previously reported to drive a 1.44-times increased risk…
Impact of Gut Microbiota in MS More Complex Than Thought, Study Shows
The presence of a particular gut bacterium widely used in probiotics, called Lactobacillus reuteri (L. reuteri), was sufficient to…
Immune Cells’ Ability to Clear Myelin Debris Is Potential Therapeutic Approach for MS, Mouse Study Shows
Oral administration of trehalose — a sugar molecule found in plants and fungi and reported to have neuroprotective effects — eased…
Majority of MS Patients in US Report Mistreatment by Caregivers in Survey
In a nationwide survey of caregiver abuse and neglect among Americans with advanced multiple sclerosis (MS), more than half of respondents…
Simple Sugar Molecule May Be Potential Myelin-repairing Therapy for MS
Oral administration of N-acetylglucosamine (GlcNAc) — a natural simple sugar sold as a dietary supplement — prevents myelin degeneration…
Iron Deficiency May Be Linked to Depression and Poorer Life Quality
Low blood levels of ferritin — the main form of iron stored in cells — are significantly associated with more…
Older Age at DMT Discontinuation Linked to Sustained NEDA in CIS Patients
Older age at disease-modifying therapy (DMT) discontinuation is the main predictive factor of sustained “no evidence of disease activity”…
NIH Awards $2.3M to Bioengineer to Advance Diagnosis, Treatment of Autoimmune Diseases
The National Institutes of Health (NIH) awarded a $2.3 million grant to a bioengineer at Indiana University’s Luddy School of…
Gilenya Remains Favorite S1P Receptor Modulator in US, But Zeposia May Catch Up, Survey Finds
Among oral sphingosine-1-phosphate (S1P) receptor modulators for multiple sclerosis (MS), Novartis’s Gilenya (fingolimod) remains physicians’ favorite in…
Pregnancy Delays Likely MS Onset by About 3 Years, Large Study Finds
After a pregnancy or childbirth, most women who went on to develop clinically isolated syndrome (CIS)Â did so about three…
#MSVirtual2020 – Fatigue Tops Survey About Relapsing MS Symptoms
Fatigue is the most impactful symptom on daily functioning in people with relapsing forms of multiple sclerosis (MS) and is…
#MSVirtual2020 – Masitinib Delays Disability Progression in PPMS, Non-active SPMS
AB Science’s lead candidate masitinib safely and effectively delays disability progression in people with primary progressive multiple sclerosis (PPMS) and non-active …
#MSVirtual2020 – Early Use of Ocrevus Slows Thalamic Atrophy in Relapsing MS and PPMS
Early use of Ocrevus (ocrelizumab) significantly slows shrinkage of the thalamus — a brain region involved in sensory…
#MSVirtual2020 – Pediatric MS Patients May Do Best on Intravenous DMTs, Study Finds
Most children and adolescents with pediatric-onset multiple sclerosis (POMS), especially those treated intravenously with a disease-modifying therapy (DMT), achieve…
#MSVirtual2020 – Remyelination Mainly Conducted by Pre-existing Myelin-producing Cells, Study Finds
Remyelination — or the restoration of lost myelin, the protective sheath surrounding nerve cell fibers — in…