MS Therapies That Deplete B-cells Appear to Work Against COVID Immunity
B-cell-depleting therapies given to adults with multiple sclerosis (MS) affect the production of…
Articles by Steve Bryson, PhD
‘Mom’s Cure’ Fundraiser Supports Work for Early MS Diagnosis via Eye Exam
The Autoimmune Registry (ARI) has opened a fundraiser, called “Cure the Mother’s Disease,”…
Lower Intestinal Fatty Acids May Contribute to MS in Women
Certain fat molecules produced by gut microbes, which have protective immune-suppressing effects and may protect against multiple…
Short Film for Hispanic/Latinx MS Patients Found to Improve Perceptions, Attitudes
A short film produced for Hispanic/Latinx people who live with multiple sclerosis (MS)…
Relapsing MS Patients May Fare Better on Zeposia Than Aubagio
Treatment with Zeposia (ozanimod) significantly reduces the risk of relapse, decreases the proportion of patients…
Immunic Sets Optimal Dose of Oral IMU-838 for Phase 3 Trials in RRMS
Interim data from a Phase 2 trial of Immunic Therapeutics’ investigational oral therapy IMU-838 (vidofludimus calcium)…
Harvard Professor Wins Dystel Prize for Uncovering MS Immune Mechanisms
The 2021 John Dystel Prize for multiple sclerosis (MS) research has been awarded…
Ocrevus Use Linked to PML in Man, 78, With PPMS, Case Report Says
A 78-year-old man with multiple sclerosis (MS) developed the brain infection progressive multifocal leukoencephalopathy…
Mouse Study Finds Potential Treatment for Myelin Repair for MS, Aging
A decline in the activity of the GPR17 gene is responsible for age-related brain…
Healthy Diet Linked to Better Mental, Physical Life Quality in Dutch Study
A healthy diet led to better physical and mental quality of life in Dutch adults with…
2 Biomarkers Found to Predict MS Onset in People with Optic Neuritis
An antibody analysis has identified two biomarkers that can be used to predict the development of…
Estrogen-based Therapy Shows Potential to Protect Vision in Mouse Model
An estrogen-based therapy, called indazole chloride (IndCl), was shown to protect against optic nerve damage in a mouse…
HTR2A Gene Changes Found Only in Progressive MS May Be New Biomarker
Scientists have discovered epigenetic changes in a gene called HTR2A, found only in immune cells isolated from people…
Study: Past Long-term DMT Use Tapers Risk of Current MS Progression
Long-term use of disease-modifying therapies (DMTs) in people with relapsing-remitting multiple sclerosis (RRMS)…
Myelin Ceramides Altered in MS, Study Finds
Levels of myelin sheath components called ceramides are altered in the blood of people with…
Prenatal Stress Linked to Worse MS Outcomes in Adulthood in Mouse Study
Exposure to stress before birth can worsen the clinical symptoms of multiple sclerosis (MS) during adulthood, a…
Review Study Examines Factors That Affect MS Patients’ Quality of Life
Disability, fatigue, depression, cognitive impairment, and unemployment are primary risk factors for a poor quality of life in people with…
Chronic Lesion Expansion in RRMS Contributes to Disease Progression, Study Reveals
The expansion of chronic white matter lesions in people with relapsing-remitting multiple sclerosis…
Nasal Delivery of Interferon-beta at Lower Doses Shows MS Treatment Potential in Mice
Nasal delivery of Rebif’s active ingredient interferon-beta, loaded in carbohydrate-based nanoparticles, reduced disease…
Aubagio Slows Grey Matter, Whole Brain Atrophy in CIS, Study Finds
Studied for the first time, Aubagio (teriflunomide) slowed the loss of cortical grey matter and whole-brain…
Tysabri Affects Immune System Beyond Known MS Target, Study Finds
Lower levels of pro-inflammatory immune signaling proteins were found in the blood of people with…
Study Flags Possible DMT Risk for MS Patients Over Age 45
The use of disease-modifying therapies (DMTs) in adults with multiple…
Tysabri Seen as Superior to Gilenya for RRMS in Limited, Head-to-head Study
Adults with active relapsing-remitting multiple sclerosis (RRMS) treated with Tysabri…
Myelin Restored on Regenerated Optic Nerve Fibers of Mice in Study
Using a two-pronged approach, researchers were able to restore myelin on regenerated nerve fibers in a mouse…
Human Placental Extract Effectively Treats MS Symptoms in Mouse Study
Human placental extract eased clinical symptoms, inflammation, and weight and myelin loss in a mouse model…
Almost Half of US MS Patients Surveyed Report Using Cannabis for Nerve Pain, Sleep
In a nationwide survey of cannabis-based therapy use among Americans with multiple sclerosis…
Rituximab Seen to Affect How B-cells Return After Treatment Stops
Rituximab, an investigational B-cell depletion therapy that target CD20 to treat people with multiple sclerosis (MS), has significant effects…
Altered Gut Microbiome, Metabolism Found in Japanese RRMS, SPMS Patients, Study Reveals
Alterations in gut bacteria and bacterial metabolism were found in Japanese people at different stages of multiple…
Immune T-cells Trigger Early MS Inflammation, Twin Study Reveals
A comparison of immune cells isolated from identical twins — in which only one of each pair was…
Ocrevus Cancels RRMS Patient’s Immunity to Chickenpox Virus, Case Study Finds
Ocrevus (ocrelizumab) eliminated the immunity, acquired through vaccination, to the varicella-zoster virus — the virus…