News

MS Incidence in UK Is Unrelated to Concentrations of Radon Gas, Researchers Find in Large-scale Study

Researchers at the University of Northamptonā€™s Radon and Natural Radioactivity Research Group (RNRRG)Ā developed aĀ methodology to study whether radon gas, an invisible and radioactive gas known to cause lung cancer, might beĀ a contributing factor inĀ multiple sclerosis. They concluded that the link between the twoĀ was weak and not statistically significant.

MS Stem Cell Therapies Show Promise, But More Work Is Needed, Researcher Tells ACTRIMS 2016

Dr. Andrew Goodman of the University of RochesterĀ discussedĀ the latest research and perspectives on stem cell strategiesĀ forĀ people with multiple sclerosis (MS), saying in a presentation at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016Ā thatĀ such therapies, while promising,Ā are not yet ready for widespread clinical use. New therapies…

Leptomeningeal Inflammation May Offer New Treatment Targets In Progressive Forms of MS

Researchers at Johns Hopkins UniversityĀ in Baltimore presented keyĀ findings today, Feb. 19, concerningĀ the presence of contrast-enhancing lesions in later stages in the relapsing-remitting experimental autoimmune encephalitis (EAE) model. The presentation was made at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016, which is ongoing through…

Results of New SPMS Study to Be Presented at ACTRIMS

At the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016, being held from Feb. 18ā€“20 inĀ New Orleans, LA, researchers haveĀ gathered to discuss ā€œProgressive MS: Bench to Bedside and Back,ā€ the meetingā€™s theme. Secondary progressive multiple sclerosis (SPMS) is one of four types of MS, and is…

Effects of Specific Antibodies on MS Neurodegeneration to Be Presented at ACTRIMS Forum

Researchers from the University of Tennessee Health Science CenterĀ plan toĀ present the results of a study investigating the contribution of specific antibodies to the neurodegeneration and neuronal dysfunction observed in multiple sclerosis (MS). The studyā€™s results are to be reported today, Feb. 18, at theĀ Americas Committee for Treatment and Research…

NIH Study into Progressive MS Biomarkers to Be Presented at ACTRIMS 2016

Scientists fromĀ the Neuroimmunological Diseases Unit at the National Institutes of Health (NIH) will present results ofĀ a study investigating several biomarkers that might leadĀ to a more sensitive and accurate diagnostic test of central nervous system (CNS) inflammation, aĀ keyĀ aspect ofĀ progressive multiple sclerosis (MS). The data is being reportedĀ today, Feb.18, at the…

ACTRIMS Session on MS Progression to Emphasize Continuing Treatment of Advancing Disease

The Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016 starts today, Feb. 18, in New Orleans, Louisiana, and runs through Saturday, Feb. 20. The opening day’sĀ Session 1, titled “Emerging Concepts in MS,” placesĀ special focus onĀ cutting-edge studies onĀ the pathogenic mechanisms in multiple sclerosis (MS), new measures of…

Anavex Life Sciences to Present Preclinical Data on Lead MS Drug Candidate at ACTRIMS 2016

Anavex Life Sciences, a biopharmaceutical company focused on the development of new therapies for neurodegenerative and central nervous system (CNS) diseases, among others, recently announced the presentation of preclinical data forĀ one of its lead drug candidates, ANAVEX2-73, as a multiple sclerosis (MS) treatment. The preclinical studyā€™s lead investigator, Dr.

US Moves Step Closer to National MS, Neurological Disease Registry with Senate Panel Vote

The U.S. Senate health committee recently passed the ā€œAdvancing Research for Neurological Diseases Act of 2015ā€ (S. 849), sponsored by Sens.Ā Johnny IsaksonĀ and Chris Murphy, whichĀ wouldĀ create a nationwide system to track the incidence and prevalence of neurological diseases, including multiple sclerosis (MS), and thatĀ one day might help lead to a…

FDA Grants ‘Breakthrough Therapy’ Designation to Genentechā€™s Ocrelizumab for PPMS

Genentech recently announced that the U.S. Food and Drug Administration (FDA) granted its investigational medicine ocrelizumab, a potential treatment forĀ primary progressive multiple sclerosis (PPMS),Ā Breakthrough Therapy DesignationĀ based on positiveĀ Phase 3 clinical trial results showing thatĀ ocrelizumab significantly reduced disability progression and other disease activity markers compared toĀ placebo. The FDA designation is…

For MS Patients, New Guidelines for Controlling Rare Brain Infection Risk Under Tysabri Treatment

The European Medicines Agency Pharmacovigilance Risk Assessment Committee (PRAC), responsible for assessing and monitoring safety issues for human medicines, completedĀ a review on the risk for progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS) patients treated with the medicine Tysabri (natalizumab). The issued guidelines have the objective of minimizing patientsā€™ risk.

MS Patients’ Likely Response to Interferon-Ī² May Be Evident in a Blood Biomarker

A new study underscoresĀ the variability of immune responses in different people with multiple sclerosis (MS) and suggests this heterogenityĀ affects responsesĀ to the commonly prescribed MS medication interferon-Ī², but blood biomarkers may exist that can help to determine those most likely to benefit from such treatment. The study,Ā “Cytokine profiles…

MS Trial to Improve Physical Activity, Lower Fatigue via Telehealth Is Enrolling Participants

A new Ā multiple sclerosis (MS)Ā clinical trial being led byĀ Case Western Reserve UniversityĀ investigatorsĀ is now recruiting 215 individuals, across 10 U.S.Ā states to assess whether the fatigue management and physical activity interventions often provided by rehabilitation centers can effectivelyĀ be offered byĀ telehealth, throughĀ a series of teleconferences and phone interviews. AnĀ National MS…

Multiple Sclerosis Co-Pay Relief Program Adds New Prescription Coverage

TheĀ Co-Pay Relief programĀ offered through theĀ Patient Advocate FoundationĀ has added a new financial assistanceĀ fund to itsĀ collection of resources for patients with multiple sclerosis (MS).Ā The new fund is now available to financially eligible MS patientsĀ with healthĀ insurance coverage to support the costs of necessary treatment medicines. “Our case management department has been…

RedHill’s Experimental MS Therapy, RHB-104, Receives Notice of Allowance on U.S. Patent

RedHill Biopharma, Ltd., an Israeli biopharmaceutical company focused on the development and commercialization of oral-administered small-molecule medicines for the treatment of inflammatory and gastrointestinal diseases, recently announced it has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for a new patent covering its…

Severe Demyelination in Non-MS Patient After TNF-Ī± Blocker Treatment Detailed in Study

TNF-Ī± blocking drugs, such as infliximab, surprised investigators when their use in people with multiple sclerosis (MS) actuallyĀ triggered demyelination. In a case report published in the journalĀ Neuroimmunology & Neuroinflammation,Ā Vanderbilt University Medical CenterĀ researchers reviewedĀ an aggressive demyelinating event in a non-MS patient treated with TNF-Ī± blockers. TNF-Ī± blockers…

MS Study Finds Lipid Antibodies Reflect Changes in Brain Volume and Lesions

Brigham and Womenā€™s HospitalĀ researchers reported that antibodies directed at lipids are associated with magnetic resonance imaging (MRI) measures of brain degenerationĀ in patients with multiple sclerosis (MS), and may potentially serve asĀ biomarkers for monitoring disease status. While the hyperintense brain lesions detected by MRI are crucial for diagnosis and therapeutic…

National Multiple Sclerosis Society Receives $20,000 From VWR Foundation

The VWR Charitable FoundationĀ recently celebratedĀ itsĀ sales teams’ accomplishments by making charitable contributions totalingĀ $100,000 in their honor to five organizations, including the National Multiple Sclerosis Society. VWR, based in Radnor, Pennsylvania, provides products, services, and solutions for the laboratory and production needs of customersĀ in the pharmaceutical, biotech, education, government, and…