News

Myelin — the fatty substance that wraps around nerve cells — is lost in multiple sclerosis (MS). Is there any way to get it back or to stop the deterioration of myelin? Researchers at MedDay Pharmaceuticals think that their drug may provide the solution. Known as MD1003, the…

National Institutes of Health (NIH) scientists may have discovered a critical immune system switch that could affect genes involved in autoimmune diseases. The ground-breaking work, published in the journal Nature, may be useful for developing treatments for autoimmune disorders such as multiple sclerosis (MS). MS is characterized by an immune system…

Opexa Therapeutics, Inc. a biopharmaceutical company headquartered in Woodlands, Texas, has announced the successful conclusion of negotiations amending its option and license agreement with Darmstadt, Germany based pharma multinational Merck’s “Merck Serono” division. Under terms of the revised agreement, Opexa will receive a $3 million payment to…

A team led by researchers from the University of Illinois at Chicago (UIC) recently revealed in the journal ASN NEURO a new genetic variation that significantly increases the risk of developing multiple sclerosis (MS) in women. The study is entitled “A Single-Nucleotide Polymorphism in…

Researchers at the Icahn School of Medicine at Mount Sinai have identified new compounds that could protect from multiple sclerosis related damage, based on studies in mice with nervous system damage, mimicking MS. The study appeared in the journal Nature Neuroscience. MS is an autoimmune…

Image credit: Yaming Wang/Bernd Zinselmeyer A new study has shown that a protein called TREM2 may inhibit microglial repair of damaged myelin in multiple sclerosis. The study appeared in the Jan. 29 issue of Acta Neuropathologica. MS is characterized by the degeneration of myelin, a fatty…

An already approved medication used for bladder problems might help to treat multiple sclerosis, according to researchers at the State University of New York at Buffalo. Lead author Fraser J. Sim, PhD, Assistant Professor in the Department of Pharmacology and Toxicology in the University at Buffalo…

Compared to healthy people, women with multiple sclerosis (MS) may have inferior levels of certain antioxidants and nutrients with anti-inflammatory properties, including vitamin E and folate, according to a new study funded by the National Institute of Neurological Disorders and Stroke (NINDS). A research team led by Dr. Sandra…

Coffee Drinking may confer the side-benefit of lowering the risk of developing multiple sclerosis (MS) in susceptible individuals, according to a meta-analysis of Swedish and American studies to be presented at the American Academy of Neurology’s 67th Annual Meeting to be held April 18-25, 2015 at the…

Do you know what biosimilar medicines do, and why they are important? If you do, then you might be in limited company. The American Autoimmune Related Diseases Association (AARDA), a national nonprofit health organization focusing on awareness of autoimmune diseases such as Multiple Sclerosis, has published a white paper…

A newly discovered molecule could play a pivotal role in inflammatory diseases, including multiple sclerosis, according to researchers at Trinity College Dublin and the University of Queensland Australia. The study was published in the journal Nature Medicine, and describes a molecule known as MCC950 that can suppress the ‘NLRP3 inflammasome’,…

The Strategic Pharma-Academic Research Consortium for Translational Medicine has awarded its first grants totaling more than $1.9 million to support research projects dedicated to autoimmune diseases. Among the recipients is researcher Yanjiao Zhou, Ph.D., who is leading a study at Washington University in St. Louis (WUSTL) focused on multiple sclerosis (MS), as…

Dr.  Jacob Sosnoff wants to know more about falling — something that few multiple sclerosis (MS) researchers focus on, even though it is a daily threat for many people with the disease. Sosnoff, an Associate Professor in the Department of Kinesiology and Community Health at the …

A new study entitled “Mercury Exposure and Antinuclear Antibodies among Females of Reproductive Age in the United States” suggests mercury exposure by seafood may increase the risk of developing autoimmune diseases in women. The study was published in the journal Environmental Health Perspectives. Autoimmune disorders…

An international group of researchers from the Center for Brain Research at the MedUni Vienna have published a paper in the Lancet Neurology journal titled “Pathological mechanisms in progressive multiple sclerosis,” documenting the pathological progress of MS since its early stages to what is known about…

A recent study led by researchers at the Centre for Addiction and Mental Health (CAMH) in Toronto, Canada revealed a promising new method for multiple sclerosis (MS) treatment. The study was published in the journal Annals of Clinical and Translational Neurology and is…

 A study published by a team of investigators at the University of Tokyo’s Institute of Medical Science and Osaka University’s Graduate School of Engineering presented new evidence demonstrating how Toll-like receptor 9 (TLR9) binds to pathogenic DNA, turning on the functions of the innate immune…

The National Multiple Sclerosis Society will receive an annual sponsorship from Showers Pass to support its efforts to improve the quality of life of patients suffering from multiple sclerosis (MS) as well as to find a cure for the disease. Showers Pass manufactures biking clothes and material and supports the…

A new study suggests that different types of physical activity might help the mental processes of people with multiple sclerosis. The research comes from the University of Illinois and the State University of New York at Buffalo, and appeared in the February 6th issue of the…

A study from German researchers might help to determine how multiple sclerosis is assessed in treatment trials. Published February 6 in the journal PLoS ONE, the study is titled “Regression to the Mean and Predictors of MRI Disease Activity in RRMS Placebo Cohorts –…

What may work better than existing drugs to treat severe multiple sclerosis? Stem cells. A phase 2 clinical study from an international group of research centers compared head-to-head autologous hematopoietic stem cell transplantation (AHSCT) and mitoxantrone in treating patients with secondary progressive or relapsing-remitting multiple sclerosis. The findings showed that…

Under development at Innate Immunotherapeutics is a special drug candidate to treat secondary progressive multiple sclerosis (SPMS). Currently, no viable therapies exist for SPMS — only less-effective means to treat SPMS patients through drugs designed for relapse-remitting multiple sclerosis — making the prospect of Innate’s experimental SPMS therapy a…

Nonprofit organization, Accelerated Cure Project for Multiple Sclerosis, is launching a national campaign called iConquerMS, which was designed by and for multiple sclerosis patients to raise awareness of the importance of health data and supporting research. On the iConquerMS portal, patients can…

Several renowned scientists working on multiple sclerosis (MS) recently joined forces to discuss and highlight the progress and knowledge gaps related to MS research, the prospects of finding a cure for the disease, and a strategy to reduce the burden the disease places on patients. A series of articles was published by the researchers in the…

Phoenix, Arizona-based Creative Medical Health (CMH) has just announced it has submitted a patent application for its proprietary mesenchymal stem cell pipeline product, indicated for autoimmune diseases. The company is already preparing to launch the product into its first line of clinical tests, which will…

The 2012 and 2014 ballots approving legalization of cannabis in four U.S. states have stirred the pot, so to speak, on a wide range of issues and nuances related to the herb — not least marijuana’s clinical use as a therapeutic agent. Medical marijuana remains a topic of debate…

Acorda Therapeutics, Inc. has released results from a Phase 1 clinical trial of rHIgM22 for multiple sclerosis, showing that the medication is safe and produces few side effects. rHIgM22 is a medication that may induce the re-wrapping of the myelin sheath that surround nerve cells,…

MicroConstants China, Inc., a company that provides preclinical, clinical, and consulting services to biotechnology and pharmaceutical companies, has just announced it has acquired international rights to the development of AA98 antibody pipeline products, indicated for the treatment of several types of cancer, multiple sclerosis, and age related macular degeneration…

MediciNova, Inc., has announced the acceptance of an abstract describing their ongoing Phase 2b clinical trial of MN-166 (ibudilast) in progressive multiple sclerosis (MS). The poster is to be presented at the American Academy of Neurology (AAN) 67th Annual Meeting, April 18 – 25, 2015 in Washington, DC. The presentation is titled…

Drug development company Rock Creek Pharmaceuticals, Inc. recently announced that a new clinical trial application with the United Kingdom’s Medicines Healthcare Products Regulatory Agency (MHRA) has been approved. The company is set to proceed with a Phase I study of its flagship pipeline product, Anatabine Citrate, a chemical that is found naturally…