News

Metabolic Changes Relating to MS Onset, Progression Focus of Study

A $957,000 grant will support research at the University at Buffalo into events that precede the onset of neurodegeneration in multiple sclerosis (MS). Specifically, the funding by the U.S. Army Medical Research and Development Command will be used to investigate possible changes in cell metabolism that lead to disease onset or progression in…

Health Canada Approves Oral Zeposia for Adults With RRMS

Health Canada has approved Zeposia (ozanimod), an oral daily treatment for people with relapsing-remitting multiple sclerosis (RRMS) in the country. Approval does not assure that Zeposia will be available to Canadian patients at no or low cost, as publicly funded prescription plans are largely administered by each…

FDA Approves Lupin’s Generic Form of Tecfidera for MS Treatment

Lupin‘s generic equivalent of Tecfidera has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of multiple sclerosis (MS), the company announced in a press release. The therapy — dimethyl fumarate delayed-release capsules — is indicated for use in people with clinically…

Rituximab Seen to Affect How B-cells Return After Treatment Stops

Rituximab, an investigational B-cell depletion therapy that target CD20 to treat people with multiple sclerosis (MS), has significant effects on the characteristics of B-cells that return after treatment is stopped, with cells being less mature yet more activated toward a pro-inflammatory state, a study showed. Treatment also…

Pathway and Its Proteins Found to Control Myelin Repair, Renewal

A pathway controlled by three proteins — Daam2, Nedd4, and VHL — was identified by researchers as a key regulator of myelin production during central nervous system development and regeneration after injury. Myelin, the protective fatty layer that covers nerve fibers and helps to speed transmission of signals between nerve cells,…

Immune Treg Cells Seen to Ease Paralysis in Mouse Model of MS

Regulatory T-cells (Tregs) — immune cells that normally dampen immune and inflammatory responses by inhibiting the activity of pro-inflammatory immune cells — enabled mice in a model of multiple sclerosis to partly recover from limb and tail paralysis, scientists reported. Tregs can do this by preventing a subtype of…

Medical Cannabis Lozenges Now Available for MS Patients in Texas

People in Texas with multiple sclerosis (MS) and other medical conditions now have access to cannabis-infused lozenges, Surterra Texas announced. Under a Texas Compassionate Use Program, cannabis-containing therapies may be prescribed to help treat various neurological and other disorders, including terminal cancer, spasticity,…