MS news notes: Bowel symptoms, MS blood test, diet study

Columnist Ed Tobias comments on the week's top MS news

Ed Tobias avatar

by Ed Tobias |

Share this article:

Share article via email
banner for

Note: This column was updated Sept. 12, 2023, to correct that Octave’s MSDA blood test is currently available and in use throughout the U.S.

Welcome to “MS News Notes,” a column where I comment on multiple sclerosis (MS) news stories that caught my eye last week. Here’s a look at what’s been happening:

MS patients hesitant to discuss bowel problems with doctors

Who wants to talk about bowel issues with neurologists? Not many of us, according to a study reported in the MS News Today story “Bowel problems often unreported by MS patients to their doctors.”

The study says about two-thirds of people with MS have bowel symptoms, such as constipation or diarrhea, but keep silent about them even though they impact their quality of life. The study mentions pain and discomfort, but I’ll add another issue that has happened to me: A full colon can put pressure on the bladder, resulting in urinary frequency and urgency.

The researchers in this study report that some patients consider the subject stigmatizing, and healthcare professionals aren’t usually proactive about diagnosing bowel symptoms. But the study suggests a solution: a self-reported questionnaire about neurogenic bowel dysfunction. It could screen patients for bowel symptoms without the need for them to talk about it.

What do you think? Have you talked about bowel problems with your neurologist? Would you be more comfortable filling out a questionnaire?

Recommended Reading
Bacteria is shown under two magnifying glasses.

Bacterial toxin epsilon in gut may be environmental driver of MS

Using a blood test and AI to measure disease activity

Another tool has joined the arsenal of MS tests, this one measuring disease progression, monitoring disease activity, and tracking responses to treatment.

Octave’s blood test accurately captures MS disease activity: Study” looks at a blood test that reviews protein levels and then uses artificial intelligence algorithms to help measure the level of new disease activity.

The MS disease activity (MSDA) blood test, according to the story, reports that “people with moderate to high MSDA scores were more than four times as likely to have at least one inflamed lesion, compared to those with low scores. … Patients with a high MSDA score were more than 20 times as likely to have two or more such lesions.”

This looks like a test that could provide important information to neurologists, especially in assessing how well a disease-modifying therapy (DMT) is working for a patient.

Diet plus supplements may improve some progressive MS symptoms

The story “Anti-inflammatory diet, synbiotics ease progressive MS symptoms” reports on a small study involving only 69 people, 77% of whom are women. I’m highlighting it because, according to these researchers, other studies have failed to look at the combined effects of diet plus supplements on people with progressive forms of MS.

In this study, some participants received daily synbiotic supplements (a mixture of probiotics and prebiotics) along with a diet that was anti-inflammatory and antioxidant rich, with 55% carbohydrates, 15% protein, and 30% fats, most of which came from olive oil, fish, and vegetables. A control group ate their usual diet plus a placebo supplement. This lasted for four months. All of the test subjects continued their usual DMTs and received guidance from a dietitian.

The group that received the supplements plus the anti-inflammatory diet reported significant reductions in fatigue and pain, as well as improved bladder control, bowel control, and sexual function compared with baseline (the start of the study). The group using a regular diet plus placebo reported that symptoms sometimes worsened.

The improvement is encouraging for the people with MS who have the ability to start and stick with a diet as strict as this one. But I’m not among them. Are you?


Note: Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those of Multiple Sclerosis News Today or its parent company, BioNews, and are intended to spark discussion about issues pertaining to multiple sclerosis.

Comments

Richard Hagan avatar

Richard Hagan

Because of my MS I have had to deal with bowel and urinary problems for years. I deal every day with these problems. I have a colostomy and self cath daily. I take a tablespoon full of Sorbitol every other day to help get my bowel moving. I am a 100% service connected veteran and I’m seen at the Palo Alto VA in CA. My care is A+++ in Spinal Cord.
Rich

Reply
Ed Tobias avatar

Ed Tobias

Thanks for sharing that info, Richard. I'm glad the care at Palo Alto VA is top-notch and thanks for your service.

Ed

Reply
Pat Meints avatar

Pat Meints

How can I get this med for digestive problems?

Reply
Ed Tobias avatar

Ed Tobias

Hi Pat,

If you're talking about symbioitic supplements, you can probably find them in a health food store. But, I'd suggest you discuss this with your doctor before you jump into using them.

Ed

Reply
Tom A avatar

Tom A

Hello Ed: “I’m not among them. Are you?”

Diet is: dinner- 6 days mashed sweet potatoes, good helping vegs (been pole beans all summer), and either chicken no skin, or salmon (add 2 tsp margarine)
Lunch: ½ egg salad sandwich, Swiss chard soup/stew (again, from garden)
Breakfast- cup oatmeal
Saturday is “special day”, most rules are off.
No salt, no sugar or added sugar, sugar free cookies. (I had been pre-diabetic for a short stint. Got rid of that)
600 MG R-Alpha Lipoic Acid x2 daily (concurrent with ongoing phase 2/3 trial)
Cup or two of skim milk, couple cups coffee with half/half and aspartame.

This has been consistent at least 10 years. Meals prepared in advance to make things simpler. 65 now, Betaseron 23 years and Ocrevus 2 years, then COVID, now nothing. Cane for stability on rough surfaces (bum leg 4 diagnoses on that ???, MS origin I suppose). Compounded MS + “old man” bladder issues, manageable. Otherwise, seem to be holding my own. How this stacks up to the diet you describe? I don’t know.

Do I feel like a spring chicken? No. I feel like a guy with MS for 35 years who has avoided the worst. Hiking, Mountain climbing, Jogging? You’ve got to be kidding! Gardening and “antiquing” I can do.

Reply
Ed Tobias avatar

Ed Tobias

Hi Tom,

Thanks for sharing all that. The diet described in the study reported on in the study used a diet similar to the Mediterranean, which is similar to what you've been doing, I think. It's great that you've been so successful with it. I guess I'm weak when it comes to food. I love my mean and ice cream, although my wife and I have been using Factor meals, which are shipped to us, for four dinners each week. It's a lot better than the processed/frozen foods that I used to eat a lot. I also exercise on weight machines and do a lot of swimming to "keep on ticking" at age 75 (43 of them with MS).

Good luck,

Ed

Reply

Leave a comment

Fill in the required fields to post. Your email address will not be published.