FAQs About Coronavirus and MS

FAQs About Coronavirus and MS


Editor’s Note: This page is updated weekly with new information related to COVID-19 testing and potential treatments in development. Click the arrow next to the date to expand the text. 

April 1, 2020

Several tests for diagnosing COVID-19 have now been granted emergency use authorization (EUA) from the FDA. As of March 31, the Advanced Medical Technology Association estimated that 17 tests had received EUAs, with more in the works. The same day, Bodysphere announced it was rolling out a test that returned results within two minutes, saying it was granted an EUA, but the FDA later refuted that claim. The test at this point has not received any FDA authorization.

 The FDA issued a warning last week that it has not authorized any test for people to use at home for COVID-19 and that people should be aware of such fraudulent tests. It also provided a list of fraudulent COVID-19 products including those that claim to prevent or treat the disease.

The agency also announced the creation of an emergency program called the Coronavirus Treatment Acceleration Program to assist in the development of treatments for COVID-19. According to the FDA, as of March 31, it is reviewing 10 therapies already in trials and 15 others in preclinical stages.

Sandoz’s malaria treatment hydroxychloroquine sulfate and Bayer Pharmaceuticalschloroquine phosphate have been granted an EUA by the FDA for the treatment of COVID-19. Both companies have donated supplies of the medications to the U.S. Department of Health and Human Services for use. Although clinical trials are needed to prove their efficacy in treating COVID-19, these therapies have shown some benefit in the lab and clinic, according to anecdotal evidence.

Among the trials recently launched for COVID-19 are a global Phase 2/3 trial (NCT04315298) testing rheumatoid arthritis treatment Kevzara (sarilumab) and a U.K.-based Phase 2 trial testing antiviral SNG001, an inhaled formulation of interferon-beta-1a. The first patients have already been treated in both trials. Another Phase 2/3 trial (NCT04315298) testing Kevzara is recruiting an estimated 400 participants in the U.S.

A Phase 2 trial, taking place in New York and Haifa, Israel, (NCT04311697) will test aviptadil for the treatment of COVID-19-associated acute respiratory distress syndrome.

Johnson & Johnson announced plans to start a Phase 1 trial by September to test its vaccine candidate Ad26 SARS-CoV-2 against COVID-19. If the trial is successful, the first batch of the vaccine could be available in early 2021 for emergency use, according to the company.

March 27, 2020

The CDC has developed a diagnostic panel for use by CDC-qualified laboratories in the U.S. and made available under an emergency use authorization (EUA) from the FDA

Other new tests include Roche Diagnostics’ cobas SARS-CoV-2 test, also granted an EUA, and the U.S. Department of Health and Human Services is funding the development of two other diagnostic tests that can detect the presence of SARS-CoV-2 within one hour.

The National Institute of Allergy and Infectious Diseases is sponsoring a randomized, controlled Phase 2 trial in the U.S. to evaluate the safety and efficacy of the broad-spectrum anti-viral treatment remdesivir by Gilead Sciences to treat the disease. Gilead has also launched two global Phase 3 trials to evaluate remdesivir’s safety and efficacy in adults with COVID-19. 

Other treatments being investigated for COVID-19 include a novel mRNA-1273 nanoparticle-encapsulated vaccine (NCT04283461), thalidomide (NCT04273581), sildenafil (NCT04304313), eculizumab (NCT04288713), recombinant human interferon-alpha 1 beta (NCT04293887), bevacizumab (NCT04305106), and antibodies from cured patients (NCT04264858), among others.

Researchers are also looking at new synthetic biology approaches by using self-assembling nanoparticles coated with viral antigens that can precisely target SARS-CoV-2. This approach can potentially overcome some of the limitations of conventional vaccines such as short shelf-life and viral evolution. 


The recent outbreak of a novel coronavirus (nCoV) strain or variant, called COVID-19, has put nations and health organizations around the world on high alert.

Multiple sclerosis (MS) patients could be at a higher risk of acquiring a nCoV infection if they are on immunomodulatory therapy.

Here are some frequently asked questions (FAQs) about this coronavirus and MS, and what to do to prevent infection.

Is there a link between MS and coronaviruses?

MS is caused by the body’s immune system mistakenly attacking the myelin sheath,  the protective covering of nerve fibers.

Early research has suggested that coronaviruses, which come in many types, can infect the nervous system and may contribute to the development of MS symptoms in some patients.

A more recent study has shown that a particular strain of the human coronavirus (HCoV), associated with respiratory tract infections, might be able to infect the brain and induce neurological diseases with unknown origins, such as MS, encephalitis, Parkinson’s, and Alzheimer’s disease.

What is COVID-19?

COVID-19 or coronavirus disease 2019, officially designated SARS-CoV-2 (for severe acute respiratory syndrome coronavirus 2), is a strain of the virus first identified in Wuhan, capital of the Hubei Province in China, in December 2019.

COVID-19 is a new strain of the virus, one not previously seen in humans.  It is still unclear how it causes disease.

What are the symptoms of a COVID-19 infection?

Symptoms of a typical COVID-19 infection include fever, cough, and difficulty breathing. Symptoms can appear between two to 14 days after exposure to the virus and are usually mild. But they can be severe in some people.

Is COVID-19 the same as SARS or MERS?

No. Although COVID-19 shares genetic similarities with viruses causing severe acute respiratory syndrome (SARS) and Middle-East respiratory syndrome (MERS), it is different from these viruses.

There have been no cases of SARS reported anywhere in the world since 2004.

Am I at higher risk of COVID-19 as an MS patient?

You may be at a higher risk of acquiring a COVID-19 infection if you are on an approved disease-modifying therapy, such as immunomodulatory medications. This is because these therapies weaken parts of the immune system, and may make you more susceptible to any infection.

That said, this particular strain of the coronavirus is very new. Not much information is available as to exactly how it might affect people with MS.

Should I get tested for COVID-19 if I have MS?

You should immediately get tested for COVID-19 if you experience any of the symptoms described above. You should also get tested if you have been in close contact with someone known to be infected with COVID-19, or have recently traveled to areas with ongoing outbreaks.

How does COVID-19 spread?

Current evidence suggests that COVID-19 spreads from person-to-person via respiratory droplets that are released by coughing, sneezing, or breathing.

There is no evidence to date suggesting that COVID-19 can be transmitted through food or imported goods. Although the virus has its origins in animals, there currently are no reports of household pets becoming infected with COVID-19 or transmitting it to people.

Is a treatment available for COVID-19?

Currently, no medication or vaccine approved by the U.S. Food and Drug Administration (FDA) exists to treat COVID-19. If the virus has infected you, you should rest and take a lot of fluids. If your symptoms are severe, you should be hospitalized.

How can I prevent the spread of COVID-19?

Following personal hygiene practices are recommended to protect you, and to help prevent the spread of COVID-19:

  • Wash your hands often with soap, lathering front and back of hands and fingers for at least 15 to 20 seconds. If soap is not available, use a hand sanitizer that contains at least 60% alcohol
  • Avoid close contact with someone who is ill; remain at least 6 feet or 1.8 meters apart
  • Stay at home if you are sick
  • Cover your cough or sneeze with a tissue paper, and then dispose of it
  • Disinfect frequently touched surfaces and objects
  • Avoid touching your eyes, nose, and mouth with unwashed hands

Should I wear a face mask?

You should wear a face mask if you are confirmed to have a COVID-19 infection or if you are showing symptoms. Health professionals and caregivers working with COVID-19 patients should also wear face masks.

The Centers for Disease Control and Prevention (CDC) does not recommend healthy individuals wear a face mask. But those who might be vulnerable — like MS patients — might want to consult with their doctor or specialist, and use a face mask if it is recommended.

What tests exist to detect COVID-19?

The CDC has developed a diagnostic panel to detect SARS-CoV-2 that is being shipped to all CDC-qualified labs in the U.S., and to qualified international laboratories.

The CDC is also working to develop a blood test that can identify the presence of antibodies against the SARS-CoV-2 virus.

Does a negative test mean I’m not infected?

A negative test result means that the COVID-19 virus was not found in a person’s sample. However, it is possible that early stages of infection by this virus may not be detected with the test.

A negative test in a person who clearly has COVID-19-like symptoms likely means that the COVID-19 virus is not causing the present illness.

What travel considerations should I take?

The usual tips and suggestions for MS patients wanting to undertake travel still apply.

The CDC recommends avoiding non-essential travel to areas with an ongoing spread of COVID-19 infections: China, South Korea, Iran, Italy, and Japan at the moment.

If you cannot avoid travel, ensure that you maintain proper hygiene as described above and try to avoid places where you come into close contact with large groups of people.


Last updated: Mar. 5, 2020


Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

Total Posts: 12
Özge has a MSc. in Molecular Genetics from the University of Leicester and a PhD in Developmental Biology from Queen Mary University of London. She worked as a Post-doctoral Research Associate at the University of Leicester for six years in the field of Behavioural Neurology before moving into science communication. She worked as the Research Communication Officer at a London based charity for almost two years.

How useful was this post?

Click on a star to rate it!

Average rating 4.3 / 5. Vote count: 238

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?

Leave a Comment

Your email address will not be published. Required fields are marked *

Pin It on Pinterest

Share This