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Ocrevus (Ocrelizumab) for Multiple Sclerosis

Last updated March 17, 2022, by Patricia Silva, PhD

Fact-checked by Ines Martins, PhD

Ocrevus is an injectable disease-modifying therapy approved for relapsing forms of MS

FAQs about Ocrevus

Ocrevus was approved in March 2017 for the treatment of adults with relapsing forms of MS. Patients with clinically isolated syndrome, relapsing-remitting MS, and active secondary progressive MS can be prescribed this medication, as can individuals with primary progressive MS. The conventional infusion time is about 3.5 hours, but a two-hour infusion was approved in 2020 for those who experienced no infusion reactions after the first doses of Ocrevus.

According to animal studies, Ocrevus may cause harm to a developing fetus. Patients able to become pregnant should use contraception while on Ocrevus, and for at least six months after stopping the therapy.

There are no known interactions between Ocrevus and alcohol. However, since alcohol can interfere with some disease symptoms and medications, patients are advised to discuss with their healthcare provider whether it is safe to drink while on Ocrevus.

As each person may react differently to medications, there is no standard timeline for how soon Ocrevus starts to work. In clinical trials, Ocrevus induced a rapid and marked depletion of B-cells within two weeks after the first dose.

Hair loss and weight gain were not reported as side effects of Ocrevus in clinical trials, but there have been some isolated reports of hair loss in people receiving this medication. Patients are advised to talk with their healthcare provider if they experience any such issues.

Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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