May 5, 2017 News by Joana Fernandes, PhD Burden of Multiple Sclerosis Relapses Is Underappreciated, Study Says The burden of moderate-to-severe relapses in multiple sclerosis (MS) patients is underappreciated, according to a study sponsored by the pharmaceutical companyĀ Mallinckrodt. Researchers discussed the findings at the American Academy of Neurology’s 69th annual meeting in Boston, April 22-28. The title of the presentation was āThe Economic Burden Of…
May 4, 2017 News by Joana Fernandes, PhD Cladribine Tablets Reduce Risk of MS Progression and Relapse, Clinical Trial Shows Cladribine tablets reduce the risk of disability progression and relapse in patients with relapsing multiple sclerosis (MS), the CLARITY clinical trial indicates. The treatment was also well-tolerated and had a good safety profile, according to a presentationĀ at the Annual Meeting of the American Academy of Neurology (AAN)Ā in Boston,…
May 2, 2017 News by Patricia Silva, PhD Remyelination Candidate Opicinumab Failed in Phase 2 Trial in MS, But Biogen Won’t Give Up Although a Phase 2b trial of the remyelination drug candidate opicinumabĀ (also known as anti-LINGO-1 and BIIB033) failed to meet its primary goal of improving disability in relapsing and secondary progressive multiple sclerosis (MS), researchers believe the drug did cause āfairly strongā improvements. The trial evaluated four doses of the…
April 28, 2017 News by Joana Fernandes, PhD Siponimod Slows Progression of MS Disability, Phase 3 Clinical Trial Shows SiponimodĀ slows the progression of multiple sclerosis patients’ disability, a Phase 3 clinical trial indicates. The therapy reduced the risk of disability progression in patients with secondary progressive multiple sclerosis (SPMS) by 21 percent over three months, researchers said. At six months, the reduction was 26 percent, they said. Researchers…
April 28, 2017 News by Patricia Silva, PhD Lemtrada Might Outperform Ocrevus in Preventing MS Relapses, Italian Researchers Say Lemtrada (alemtuzumab) may be more effective in preventing relapses in multiple sclerosis patients than the newly approved Ocrevus (ocrelizumab), according to a study presented April 28Ā atĀ the American Academy of Neurology (AAN) 2017 Annual MeetingĀ in Boston. TheĀ study, supported by Sanofi Genzyme and Bayer HealthCare Pharmaceuticals, compared…
April 27, 2017 News by Patricia Silva, PhD Genentech Highlights Rapid Actions of MS Therapy Ocrevus at AAN Meeting Within the first two months of treatment, Ocrevus (ocrelizumab) reduced relapses in multiple sclerosis (MS) patients by more than half compared to those on Rebif, and almost completely prevented new brain lesions, according to data underscoring the drug’s rapid effects. Researchers from San Francisco-basedĀ Genentech and its Swiss parent…
April 26, 2017 News by Joana Fernandes, PhD Sanofi Genzyme to Present New Data on MS Treatments Lemtrada and Aubagio Sanofi Genzyme will present new results on follow-up studies of its products Lemtrada (alemtuzumab) and Aubagio (teriflunomide), both of which have been approved for the treatment of relapsing-remitting multiple sclerosis (RRMS). The new data will be presented at the American Academy of Neurology (AAN) Annual MeetingĀ taking…
April 24, 2017 News by Patricia Silva, PhD ATA188, Which Kills B-Cells Targeting Epstein-Barr Virus, Shows Promise as MS Treatment An investigational treatmentĀ called ATA188 that wipes out B-cells targeting the Epstein-Barr virus (EBV) has shown promise as a multiple sclerosis treatment, a Phase 1 clinical trial involving a small patient group indicates. The trial, conducted in Australia, covered six people with primary or secondary progressive MS. B-cells are a…
April 20, 2017 News by Patricia Inacio, PhD Teva to Discuss MS and Huntington’s Therapies at Premier Neurology Conference Teva Pharmaceutical Industries will discuss two of its multiple sclerosis therapies, one that reduces relapses and one that appears to protect nerve structure, at a premier neurology conference in Boston this month. It will also give presentationsĀ at the 2017 Annual Meeting of the American Academy of NeurologyĀ on therapies…
April 20, 2017 News by Patricia Silva, PhD AAN Annual Meeting Offers First Ocrevus Data Update Since MS Therapy’s Approval by FDA New data on the recently approved multiple sclerosis (MS) drug Ocrevus (ocrelizumab) will be presented at the upcoming American Academy of Neurology (AAN) Annual Meeting 2017, which will take place April 22-28 in Boston. The meeting is the first scientific conference focusing on neurology since the U.S.
April 19, 2017 News by Patricia Inacio, PhD Sanofi Genzyme to Discuss Three Multiple Sclerosis Therapies at Boston Event Sanofi GenzymeĀ will discuss three of its multiple sclerosis therapies at theĀ American Academy of Neurology annual meetingĀ in Boston, April 22-28. The presentations will cover two approved treatments for relapsing MS ā LemtradaĀ (alemtuzumab) and AubagioĀ (teriflunomide) ā and one that has been in a Phase 1 clinical…