December 2, 2015 News by Patricia Silva, PhD Experimental Relapsing-Remitting MS Drug Treatment Advancing Synthetic Biologics, which specializes in the development of therapies forĀ pathogen-specific diseases, recently announced theĀ publication of new and positive data on results from a Phase 2 clinical trial evaluating the companyās product Trimestaā¢ as a treatment for relapsing-remitting multiple sclerosis (RRMS) in women. Professor Rhonda Voskuhl, director of theĀ Multiple Sclerosis Program…
November 30, 2015 News by Patricia Silva, PhD People with Relapsing NMOD Invited to Enter Phase 3 Study The National Multiple Sclerosis Society recently announced that a research team is recruiting 132 patients with a diagnosis of neuromyelitis optica spectrum disorders (NMOSD) for a Phase 3 clinical study comparing an experimental medicine with an inactive placebo. NMOSD is a rare disorder caused by immune system cells attacking…
November 4, 2015 News by Patricia Silva, PhD Alkermes’ Multiple Sclerosis Therapy ALKS 8700 Yields Positive Clinical Trial Data Alkermes plc, a fully integrated global biopharmaceutical company, recently provided a regulatory update and positive clinical trial data for ALKS 8700, an oral, innovativeĀ and proprietary monomethyl fumarate (MMF) compound that is being developed to treat multiple sclerosis (MS). ALKS 8700 is being developed to quickly and efficiently convert…
November 3, 2015 News by Patricia Silva, PhD Multiple Sclerosis Pilot Study Evaluating PoNS Yields Promising Results Helius Medical Technologies, Inc., a company dedicated to neurological wellness, recently announced that the multiple sclerosis (MS) pilot study assessing the companyās investigational Portable Neuromodulation Stimulator (PoNSā¢) device has met all of the studyās goals. PoNS is a non-invasive device that allows the delivery of neurostimulation through the…
October 22, 2015 News by Margarida Azevedo, MSc Biogen’s TYSABRI for Secondary Progressive MS Fails to Meet Phase 3 Trial Endpoints Biogen Inc. recently reported that the Phase 3 ASCEND clinical trial study testing TYSABRI efficacy in patients with secondary progressive multiple sclerosis (SPMS) did not achieve its primary and secondary goals. According to the company, the comprehensive results of the study will be revealed at a future medical conference.
October 15, 2015 News by Maureen Newman The Future of Stem Cell Therapy for Multiple Sclerosis Patients Relies on Clinical Trial Participation Among the different therapeuticĀ approaches being explored for treating MS,Ā adult stem cell therapy continues to beĀ one of the most discussed and anticipatedĀ in the MS community. āStem cellsā ā the common term for undifferentiated, self-renewing proliferating cells āĀ are currently being investigated for their ability to treatĀ patients in a wide range of disease…
August 26, 2015 News by Patricia Silva, PhD Clinical Studies of Cannabinoid Capsules for MS Expected Later This Year Multiple sclerosis (MS) is a disease characterized by the destruction of insulating covers on nerve cells by the immune system. The most common form for the disease, relapsing-remitting MS, is characterized by clearly defined attacks of decreasing neurologic function (relapses) followed by partial or complete recovery…
August 24, 2015 News by Charles Moore Clinical Trials Study Cannabis Chewing Gum for MS-Associated Pain and Spasticity AXIM Biotechnologies, Inc. (AXIM)’s clinical trials testingĀ a new pharmaceutical-grade cannabis chewing gum treatment option for Multiple Sclerosis (MS) pain and spasticity are drawing lots of popular and specialty media attention, with reports in Multiple Sclerosis News Today, Marketwatch, Yahoo! Finance, Wall Street Journal, CNN Money,…
August 10, 2015 News by Patricia Inacio, PhD Apitope Completes Enrollment for Phase IIa Trial for Relapsing Multiple Sclerosis Apitope, a biocompany devoted to drug discovery and development for autoimmune diseases, announced that its partner Merck Serono has concluded the recruitment of participants forĀ its Phase IIa Trial on relapsing multiple sclerosis, (known as a Phase IIa study of ATX-MS-1467 or also M2736) The drug, ATX-MS-1467, is an…
July 8, 2015 News by Isaura Santos 1200 People With Relapsing MS Needed For RPC1063, Avonex Clinical Trials Clinical investigatorsĀ worldwide are beginning to recruitĀ 1,200 patientsĀ with relapsing multiple sclerosisĀ for a study assessingĀ the effectiveness of two different doses of RPC1063 (Receptos, Inc.), an experimental oral therapy, and AvonexĀ® (interferon beta-1a, Biogen Inc.) in order toĀ reduce relapse rate in patients. This study, called the Sunbeam Study, is being funded by…
June 23, 2015 News by Patricia Silva, PhD MedDay Reveals Promising Data on Progressive Multiple Sclerosis Therapy MedDay, a biotechnology company dedicated to developing therapies for nervous system disorders, recently announced encouraging data on its pivotal Phase III clinical trial (MS-SPI) assessing the safety and efficacy of the company’s investigationalĀ therapy MD1003 for the treatment of progressive multiple sclerosis (MS). The data was presented at The…
June 12, 2015 News by Patricia Silva, PhD Adamas Begins Phase 2 Multiple Sclerosis Study for Patients with Walking Impairment Adamas Pharmaceuticals, Inc., a specialty pharmaceutical company developing therapies forĀ chronic disorders of the central nervous system, recently announced the beginning of a Phase 2 study that willĀ assess the efficacy of amantadine HCl (ADS-5102) in patients with a diagnosis of multiple sclerosis (MS) who suffer from walking impairments. “We are…
April 22, 2015 News by admin Two Already-Approved Medications Could Treat MS Two already available medicationsĀ could be used to treatĀ multiple sclerosis (MS). In a newĀ study titled, “Drug Based Modulation of Endogenous Stem Cells,” published in the journal NatureĀ on April 20, 2015, scientists report that twoĀ drugs couldĀ activate stem cells in the brain, possibly repairing MS-induced damage to…
April 13, 2015 News by admin Biogen to Focus on RRMS Disease Management, Treatment at Upcoming Conference Biogen plans toĀ present new clinical data at the 67th American Academy of Neurology (AAN) Annual Meeting in Washington D.C., April 18 ā 25, 2015, including numerous presentations focusing on multiple sclerosis. Ā In a company press release, Biogen statedĀ āAt AAN, we will feature new scientific data, including research highlighting the…
April 10, 2015 News by Patricia Silva, PhD MedDay To Release Phase III Clinical Trial Results for Experimental Progressive Multiple Sclerosis Therapy MedDayĀ recently announced in a news releaseĀ that it is preparing to release the design and results of its clinical trial to assess the safety and efficacy of MD1003 in primary and secondary progressive multiple sclerosis (MS) treatment. Data on the Phase III clinical trial (MS-SPI) will be presented…
April 1, 2015 News by Patricia Silva, PhD Statins Therapy in Multiple Sclerosis Yields Controversial Results Researchers at the IRCCS Centro Neurolesi āBonino-Pulejoā and the University of Messina in Italy have performed a review on the immunomodulatory activity reported for statins in the treatment of multiple sclerosis (MS) and on clinical trial results. The study was published in the journal Pharmacological…
March 25, 2015 by Maureen Newman Low Dose Naltrexone Review for MS Reveals High Safety Profile, Mixed Results on Benefits in Multiple Studies One of the most widely disputed treatments for multiple sclerosis is low dose naltrexone (LDN). While a plethora of patient testimonies and anecdotal evidence suggest immense benefits of LDN for multiple sclerosis, many clinicians are wary due to the lack of FDA approval outside of treating heroin and alcohol addiction.
March 2, 2015 News by admin Multiple Sclerosis Treatments Benefit From Discovery of New Inflammatory Molecule A newly discovered molecule could play a pivotal role in inflammatory diseases, including multiple sclerosis, according to researchers at Trinity College Dublin and the University of Queensland Australia. The study was published in the journal Nature Medicine,Ā and describes aĀ molecule known as MCC950 that can suppress the ‘NLRP3 inflammasome’,…
February 16, 2015 News by Maureen Newman Stem Cells Used to Treat Secondary Progressive Patients in Clinical Trial What may work better than existing drugs to treat severe multiple sclerosis? Stem cells. A phase 2 clinical study from an international group of research centers compared head-to-head autologous hematopoietic stem cell transplantation (AHSCT) and mitoxantrone in treating patients with secondary progressive or relapsing-remitting multiple sclerosis. The findings showed that…
December 19, 2014 News by Patricia Silva, PhD Mapi Pharma Treats First RRMS Patient with Once-A-Month GA Depot Mapi Pharma Ltd.,Ā a development stage pharmaceutical company specializingĀ in the development of high-barrier to entry and high-added value generic drugs, announced it has treated the first patient in theĀ Phase IIa study of GA Depot forĀ relapsing-remitting multiple sclerosis (RRMS). Lead investigatorĀ ProfessorĀ Ariel Miller, M.D., Ph.D., Head of the Multiple Sclerosis & Brain…
July 31, 2014 News by Patricia Silva, PhD After Delay, Innate Immunotherapeutics’ MIS416 Trial For Secondary Progressive MS Therapy To Begin Enrolling in August In spite of an eight week delay, New Zealand-basedĀ Innate ImmunotherapeuticsĀ is still planning to enroll patients for its phase 2b clinical trial that will study theĀ experimental drugĀ MIS416Ā for secondary progressive MS. The clinical research organization (CRO) involved in the management of the trial informed the company about the…