September 15, 2020 News by Joana Carvalho, PhD #MSVirtual2020 – Lesions First Seen on Nerves of GI Tract in Mouse Model of MS Before signs of neurodegeneration in the brain and spinal cord are evident in mice with experimental autoimmune encephalomyelitis (EAE) ā which resembles humanĀ multiple sclerosis (MS) ā signs can first be found in the network of nerves innervating the gastrointestinal (GI) tract, a study reports. Additional research is needed…
February 5, 2020 News by Alberto Molano, PhD QyScore, Imaging Software that Analyzes MRI Markers of Brain Disease, Earns FDA Clearance The U.S. Food and Drug Administration (FDA) has grantedĀ 510(k) clearance forĀ QyScore, a cloud-based imaging software for the automated quantification of key magnetic resonance imaging (MRI) markers of central nervous system (CNS) disease. MRI is an important tool for diagnosing multiple sclerosis and other CNS disorders. By…
February 3, 2020 News by Vanessa Pataia Interaction Between Different Immune Cells May Lead to New MS Therapies, Study Suggests Scientists discovered new interaction between immune cells from the central nervous system (CNS) ā consisting of the brain and spinal cord ā and immune cells from the blood that may lead to new treatments for multiple sclerosis (MS) and other neurological diseases.
July 22, 2019 News by Jose Marques Lopes, PhD Microbes in Gut Protect Nervous System After Viral Infections, Study Suggests Gut microbes prime immune cells called microglia to protect the brain and nervous system from neurological damage due to viral infections, according to new research in mice. The findings suggest that maintaining a healthy and diverse microbiota ā the population of bacteria, fungi, and viruses within the body, especially the…
June 17, 2019 News by Patricia Inacio, PhD Human Blood-brain Barrier in a Chip, Created in the Lab, May Help Design New Therapies, Study Shows By tweaking stem cells in a laboratory, researchers were able to generate a model of the human blood-brain barrier (BBB) in a chip. The BBB is a highly selective barrier that is damaged in multiple sclerosis (MS), allowing immune cells to reach the central nervous system and damage…
November 27, 2018 News by Ana Pena PhD Homotaurine Compound May Be New Class of Treatment for MS, Mouse Study Suggests Homotaurine, a compound proven safe for humans in long-term clinical trials, has eased autoimmune responses, brain inflammation, and multiple sclerosis-like symptoms in a mouse model of the disease, a study has found. The findings represent proof-of-principle evidence that homotaurine may represent a new potential class…
November 6, 2017 News by Iqra Mumal, MSc Thin But Persistent Regrowth of Myelin Layers Sign of Health in CNS, Study Says The generation of a thin myelin sheath during remyelination ā one that continues to protect nerve cells over time ā is indicative of the long-term health and activity of the central nervous system (CNS) in demyelinating diseases such as multiple sclerosis (MS), a new study shows. These findings, which aim…
March 20, 2017 News by Patricia Inacio, PhD EBI2 Receptor Facilitates T-cell Invasion of Brain in MS, Animal Study Shows Scientists have identified a receptor that promotes the influx of damaging immune T-cells into the brain of a mouse model of human multiple sclerosis (MS). The study, āEBI2 is highly expressed in multiple sclerosis lesions and promotes early CNS migration of encephalitogenic CD4 T cells,ā appearedĀ in the…
September 16, 2016 News by Patricia Inacio, PhD #ECTRIMS2016 – Protein Seen as New Target in Preventing Brain Inflammation in MS Researchers found that blocking a protein,Ā known asĀ integrin alpha 8, may workĀ to prevent inflammation in the central nervous system of patients with multiple sclerosis (MS). The results were revealedĀ in an oral presentation, āIntegrin alpha8 is a novel mediator of T lymphocyte migration across the CNS barriers,ā atĀ theĀ 32nd Congress of theĀ European Committee…
September 16, 2015 News by Patricia Silva, PhD Aphios Awarded Grant for Cannabinoid Production To Develop Therapeutic Agent for MS Aphios Corporation, a green biotechnology company based inĀ Massachusetts that uses environmentally sustainable technologies, recently announced it was awarded the Phase II portion of a Fast Track SBIR grant from the National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) for the production of cannabidiol (CBD) from marijuana.
May 20, 2015 News by Kara Elam Genzyme Announces New Research Collaboration With Ablynx for Innovative Multiple Sclerosis Therapeutic Project This week, Belgian-based biopharmaceutical company Ablynx announced they have entered into an exclusive research collaboration with Genzyme, a Sanofi company, to investigate the use of Nanobodies as part of a targeted therapeutic strategy for multiple sclerosis (MS). Ā The research will utilize Genzymeās early-stage MS research programs involving neuroprotection…