myelin

Pathway and Its Proteins Found to Control Myelin Repair, Renewal

A pathway controlled by three proteins ā€” Daam2, Nedd4, and VHL ā€” was identified by researchersĀ as a key regulator of myelin production during central nervous system development and regeneration after injury. Myelin,Ā the protective fatty layer that covers nerve fibers and helps to speed transmission of signals between nerve cells,…

#MSVirtual2020 ā€“ Remyelination Mainly Conducted by Pre-existing Myelin-producing Cells, Study Finds

Remyelination ā€” or the restoration of lost myelin, the protective sheath surrounding nerve cell fibers ā€” in multiple sclerosis (MS) depends mainly on pre-existing oligodendrocytes (myelin-producing cells), rather than on newly-generated oligodendrocytes, according to a recent study. The data also showed that perineuronal, or satellite,…

NeuroScientific Biopharmaceuticals’ Lead Candidate, EmtinB, Shows Promise in Preclinical Model of MS

NeuroScientific Biopharmaceuticals (NSB)ā€™s lead candidate EmtinBĀ induces significantly greaterĀ myelin regeneration in a cellular model ofĀ multiple sclerosisĀ (MS) than the market-leading therapyĀ Copaxone, the company announced. ā€œThese results represent a potential breakthrough in the treatment of MS as there are currently no approved therapeutic drugs available to patients that…

New Nanosensor May Help to Diagnose MS at Early Stages

A new tiny sensor is able to detect antibodies against myelin,Ā the protective coating of nerve cell axons whose destruction is a hallmark ofĀ multiple sclerosisĀ (MS), potentially allowing for a diagnosis in early disease stages, researchers report. It also offers the possibility of distinguishing multiple sclerosis from neuromyelitis optica, a…