Testing cognitive abilities — like learning and memory, processing speed, and verbal fluency — can give valuable clues as to how well people with multiple sclerosis (MS) are able to go about their daily lives, according to a review study led by Kessler Foundation researchers. Neuropsychological tests are of “significant predictive…
symptoms
For the last few months, urinary tract infections (UTIs) have been the main subject of this column. My current disease-modifying therapy, Ocrevus (ocrelizumab), has had a significant impact on my multiple sclerosis (MS). The only downside is that Ocrevus attacks B-cells in the body, increasing the risk…
The other night, I had an MS dream. In it, I was able to lift my left leg as well as I can my right one, regardless of my weak hip flexor. I don’t usually know what’s triggered a dream, but this time I did: My Bioness L300 had…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “Do you use pain meds to get through day to day life?” from…
Bladder and bowel problems, such as constipation and fecal incontinence, are associated with a higher level of fatigue in people with multiple sclerosis (MS), according to a study in Australia. The findings also showed that greater fatigue and experiencing bowel and bladder problems are associated with…
Acthar Gel (repository corticotropin injection) eased flare-up symptoms in patients with multiple sclerosis (MS) experiencing relapses, top-line data from an observational registry study shows. Acthar Gel, a medication developed and marketed by Mallinckrodt Pharmaceuticals, is a compound that enhances the production of steroids in the…
I have been fighting multiple sclerosis (MS) for seven years now. I’ve changed a lot since getting diagnosed. I’ve become more aware of my body and the ways MS has changed my life. Nothing stopped me from graduating from college, but I’ve still faced many challenges…
Profiling Inflammatory Markers in Cerebrospinal Fluid of Importance in Active MS, Case Study Finds
Careful profiling of inflammatory markers in cerebrospinal fluid (CSF) of multiple sclerosis patients, coupled with standard exams and scans, helps in understanding disease evolution and treatment response, a case report suggests. It followed a relapsing-remitting multiple sclerosis (RRMS) patient whose inflammatory markers in the CSF remained high over time, and…
A new large-scale genetic map implicates broad immune system dysfunction in patients with multiple sclerosis (MS), suggests a key role of brain immune cells called microglia, and indicates an MS-related gene variant located in the X chromosome. Altogether, the findings — the result of the largest reported study…
Trigger for MS and Other Immune Diseases May Be T-cells in Early Activation State, Study Reports
A specific type of immune cell in a particular activation state is linked to such immune diseases as multiple sclerosis (MS) and inflammatory bowel disease (IBD), a collaborative research study found. Disease-associated genetic variants — changes in DNA sequences or mutations in genes — can affect the response of immune…
I’ve been whinging for months now about struggling on through near-constant urinary tract infections. This week’s joyous occasion was finally having a poo (hurrah), but then not having the energy to do anything about the result (boo). I’d spent something like five hours attacking the problem with my new…
Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis announced it will become the first U.S. hospital to test a nerve cell-derived component known as neurofilament light chain (NfL) in multiple sclerosis (MS) patients. Led by the Owosso, Michigan, hospital’s chief of neurology and MS director, Rany Aburashed, DO,…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “Is it an MS Diagnosis or is it something else? ” from July…
A diagnosis of multiple sclerosis (MS) often leaves patients and their families with many unanswered questions. It can be hard to find information, connect with other patients, and find support. Here are some frequently asked questions and answers about MS: What is MS? MS is an autoimmune disease —…
A new app might make it easier for healthcare providers to assess cognitive function in people with multiple sclerosis (MS). The app was described in the study, “iCAMS: Assessing the Reliability of a BICAMS Tablet Application,” published in the International Journal of MS…
The volume of atrophied (shrunken) regions in the brain, as visible through magnetic resonance imaging (MRI) scans, can predict disease progression in people with multiple sclerosis (MS), new research reveals. The finding was published in the journal Radiology in an article titled, “Atrophied Brain T2 Lesion Volume…
“Events, my dear boy, events.” Because of my own political proclivities, I don’t tend to quote old Conservative prime ministers, unless, of course, it’s Winston Churchill. In his semi-youth, he crossed the floor to join the Liberal Party twice: “Anyone can rat, but it takes a certain amount of…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “Does PML worry you?” from April 18. The world of multiple sclerosis (MS)…
I saw a praying mantis this morning. The long, leaf-like oddity caught me off guard. I was transfixed by the beautiful specimen, its prayerful state contrasting starkly with its violent mating ritual. The female is known to eat the head of the male — a shift in temperament at…
The U.S. Federal Trade Commission (FTC) sent warning letters to three companies that sell cannabis-based products containing cannabidiol (CBD), cautioning them that making unsubstantiated claims about the health benefits of CBD could lead to legal action. The agency “urges the companies to review all claims made for their…
Patients with progressive multiple sclerosis (MS) have higher levels of protein markers of activated glial cells than those with relapsing-remitting MS (RRMS) or patients with other neurological disorders, according to a new study. The findings also indicated that scoring the extent of glial involvement in relation to nerve…
Damage to nerve cells appears to occur years before people with multiple sclerosis (MS) begin to show symptoms and is evident in a likely biomarker, new data suggest. Researchers found raised levels of neurofilament light chain (NfL), a protein associated with nerve cell damage, in blood samples collected six years…
Infection with the human herpesvirus (HHV)-6A may increase the likelihood of having multiple sclerosis (MS), according to a new national study in Sweden. The research, “Serological response against HHV-6A is associated with increased risk for multiple sclerosis,” was presented by Anna Fogdell-Hahn, PhD, associate professor at the…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “When do you tell your employer about your MS?” from Jan. 15,…
Imagine that you’re sitting in your 7 a.m. clinical psychology class and fighting to stay awake. Energy drinks were part of my morning routine in college. I usually went to bed around the same time every night, so I couldn’t figure out why I was still tired and…
Serum neurofilament light chain (sNfL) in the blood — a proposed biomarker for multiple sclerosis (MS) — is linked with worse neurologic function at levels above a certain threshold, according to data from a large, real-world study. Kathryn Fitzgerald, assistant professor at the Johns Hopkins School of…
Brain inflammation in multiple sclerosis (MS) hijacks immature myelin repair cells, not only preventing myelin restoration but also promoting sustained inflammation and immune attacks against myelin, a preclinical study shows.
Under Pressure
There’s always something. The trouble with a mélange of complex medical issues is that one good action often can lead to a bad secondary one. It’s like a game of consequences that unfortunately not only injures your psyche, but also leaves a mark on the body. In my case, it…
Feeling tired, depressed, or anxious? Maybe it has to do with your social cognition. Social cognition involves empathy and recognizing the emotions that are revealed by someone’s facial expression. That expression may show fear or disgust. Or it may warn us of danger. Social cognition also involves the…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “How do you feel about journaling? It’s a good way to keep track of…