T-cells Targeting Epstein-Barr Virus at High Levels in MS Patients
People with multiple sclerosis (MS) have significantly more T-cells equipped with receptors that specifically recognize the Epstein-Barr virus (EBV)…
Articles by Marisa Wexler, MS
Soft Inner Layer Surrounding Brain May Be MS Target, Study Finds
In multiple sclerosis (MS), disease-causing immune T-cells enter the brain and spinal cord through the protective soft membranes covering…
Tysabri Improves Cognition Over Long-term in Early RRMS Patients
Long-term treatment with Tysabri (natalizumab) significantly improves cognitive function and increases the chance of disability reduction in people with…
High-efficacy DMTs Boost Mid-term Prognosis for Relapsing MS: Study
People with relapsing multiple sclerosis (MS) treated with Tysabri (natalizumab) or Gilenya (fingolimod) are less likely to…
More Microscopic Brain Damage Seen in SPMS Than in RRMS
People with secondary progressive multiple sclerosis (SPMS) have more microscopic damage in normal-appearing brain tissue than do patients with…
Review Showcases Inconsistencies in MS Auditory, Vestibular Research
Abnormalities in the auditory and vestibular systems, which control hearing and balance, are frequently reported among people with multiple…
Approved Corticosteroid Medrysone Prompts Myelin Repair in Mice
Treatment with medrysone, a glucocorticoid approved in the U.S. as a topical treatment for certain inflammatory eye diseases, improved…
Targeting Protein Could Protect Nerve Cells via Blood-CNS Barrier
The protective barrier that prevents cells and large molecules from crossing into the central nervous system (CNS) is known to…
Ublituximab’s Benefits Over Aubagio Seen in ULTIMATE Clinical Trials
Treatment with the experimental B-cell depleting therapy ublituximab significantly outperformed Aubagio (teriflunomide) at reducing relapse rates and the…
Aquatic Exercise Found to Ease Fatigue, Improve Balance in MS
Aquatic exercise therapy can help to ease fatigue and improve balance in people with multiple sclerosis (MS), without notable…
Global Prevalence of SPMS Estimated, But Seen to Vary Widely
Worldwide, about 22 in every 100,000 people live with secondary progressive multiple sclerosis (SPMS), a review study analyzing data…
Researchers Share Strategies to Improve Clinical Trial Recruitment
Publicity in national news outlets and an online self-screening questionnaire helped improve recruitment for a clinical trial in secondary…
Healthy Connections in Brain May Be Needed for Cognitive Rehab
People with multiple sclerosis (MS) who responded to cognitive rehabilitation showed healthier connections between certain brain regions on functional…
Early Detection of Pseudobulbar Affect May Help Ease MS Symptom
In its inaugural issue, a publication from The Gerontological Society of America provides information about recognizing and managing pseudobulbar affect…
Ideals on Masculinity May Guide Health Behaviors in Men With MS
Men with multiple sclerosis (MS) show differences in health-related behaviors based on how much they value certain masculine ideals,…
Anti-CD20 Therapies Help Mount T-cell Response to COVID-19 Vaccines
People with multiple sclerosis (MS) who are on therapies that deplete antibody-producing B-cells can mount an effective T-cell immune…
Leg Nerve Stimulation Feasible, May Help With Overactive Bladder in MS
Transcutaneous tibial nerve stimulation (TTNS), a procedure sending an electric current through the skin to nerves in the legs, is…
MS Patients Miss Work Nearly 2 Times as Often, US Study Finds
People with multiple sclerosis (MS) are absent from their places of employment nearly twice as often as individuals without…
Study Shares Successful Recruitment Strategies for MS Exercise Trial
By engaging a variety of stakeholders from across the multiple sclerosis (MS) community, researchers in the U.S. Deep South…
New 3D Brain Map May Help in Disease Management: Study
A team of researchers has created a three-dimensional (3D) map of the lymphatic vessels that drain the brain, and demonstrated…
X Chromosome Gene Variations Tied to 20 Times Higher MS Risk in Women
Variations in more than a dozen genes on the sex-determining X chromosome are more common among those with multiple…
Stem Cell Transplant Found to Reduce MS Relapses, Ease Disability
Autologous hematopoietic stem cell transplant (aHSCT), a procedure that aims to “reset” the immune system, generally reduces disability and…
Ocrevus Outperforms Rebif in Preventing Myelin Loss in Trial
Two years of treatment with Ocrevus (ocrelizumab) outperformed Rebif (interferon beta-1a) at preventing myelin loss in people with…
Research on Exercise’s Protective Effects Flawed, Researchers Say
An international team of scientists is calling for more rigorous studies to test whether exercise can help protect the…
Vagus Nerve Stimulation Boosts Motor Learning in Mouse Model
Providing electrical stimulation to the vagus nerve, a large nerve that plays important roles in modulating nonconscious bodily processes like…
No Link Between MS Severity, Vitamin D-related Mutations: Study
A number of genetic variations related to vitamin D metabolism were not significantly associated with the severity of multiple…
Novel Machine Learning Technique May Help ID Tremor Specific to MS
A new machine learning strategy was able to differentiate tremor specific to multiple sclerosis (MS) from tremor related to…
Review Gives ‘Cautious Support’ to Childhood Trauma as MS Risk Factor
Most available studies suggest a connection between childhood trauma and multiple sclerosis (MS), from earlier symptom onset to potentially poorer outcomes,…
Heart Medication Digoxin Helps With Remyelination in Early Study
Digoxin, an approved medication for certain heart conditions, promoted the repair of myelin — the protective sheath around nerve fibers that…
Semi-synthetic Compound Promotes Myelin Repair in MS Mice
A man-made molecule derived from a naturally occurring amino acid was able to promote the repair of the myelin…