Stem Cell Transplant Trial Enrolls First Patient in Minnesota
A clinical trial investigating patient-derived stem cell transplants for the treatment of people with severe relapsing forms of…
Articles by Patricia Inacio, PhD
MindMaze’s Therapeutic Games Opening to More MS, Neurologic Patients
MindMaze’s animated ‘games,’ designed to aid in recovering motor and cognitive skills in people with neurological disabilities, such as…
NICE Again Says No to Adding Zeposia to Health System for England and Wales
The National Institute for Health and Care Excellence (NICE) has maintained its initial draft recommendation and will not recommend…
Conversational Bot to Promote COVID-19 Vaccination Among Patients
A conversational bot is being developed at the University of Illinois at Urbana-Champaign (UIUC) to promote COVID-19 vaccinations among…
Therini Raises $17M to Bring Antibody to Myelin-damaging Protein Into Trials
Therini Bio announced raising $17 million in a financing round to speed the development of an antibody that might treat…
CMSC and NeurologyLive Series, ‘Ever Changing Face of MS,’ Opens for Doctors
The Consortium of Multiple Sclerosis Centers (CMSC) has launched a monthly webinar series, in partnership with NeurologyLive, to keep doctors…
Gilenya Increases Patient Infection Risk, Clinical Data Suggest
The multiple sclerosis (MS) treatment Gilenya (fingolimod) is associated with a 16% greater risk of infections, compared with a…
Kesimpta Approved in UK as At-home Relapsing MS Therapy
Kesimpta (ofatumumab) has been approved in the U.K. as the first self-administered, at-home, B-cell-targeting therapy for people with relapsing…
WNT9B Genetic Variant Linked to Increased Relapse Risk
A genetic variant in the WNT9B gene and vitamin D response are both associated with a greater risk of relapses…
Phase 3 Trial of GA Depot as Monthly Relapsing MS Therapy Enrolling in US, Europe
A Phase 3 trial investigating GA Depot, a long-acting, once-a-month injectable formulation of glatiramer acetate, is…
In Real World, Tysabri Lessens Disease Activity, Reduces Relapses in Pediatric-onset MS
Off-label treatment with Tysabri (natalizumab) significantly lessens disease activity and reduces the number of relapses per year in patients with…
Pilates Helps Men With MS Gain in Balance to Lower Fall Risk, Study Finds
Pilates, done regularly, can significantly improve balance and posture in men with multiple sclerosis (MS), helping them to avoid falls…
Pack Health, With NMSS Support, Brings Coaching Platform to MS Community
The National Multiple Sclerosis Society (NMSS) is helping Pack Health, a patient engagement platform, to optimize and expand its digital health coaching…
Enrollment Complete in Phase 2 Trial Testing Temelimab
GeNeuro has completed patient enrollment in its ProTEct-MS Phase 2 clinical trial evaluating temelimab as a treatment for multiple…
KIF5A Protein Levels in CSF May Act as Biomarker of Progressive MS
The levels of KIF5A protein are elevated in the cerebrospinal fluid (CSF) — the liquid surrounding the brain and spinal…
Cancer Therapy Seen to Protect Blood-brain Barrier, Ease MS in Mouse Model
Imatinib, a cancer treatment, stopped an injury response mechanism of the central nervous system (CNS) from activating, damage to which…
MS Patient Donates $700,000 to Ochsner MS Work
Desi Harrison, a multiple sclerosis (MS) patient and president of the nonprofit MS Warriors for a Cause, has donated…
Less Sunlight Means More Risk of Relapse, Disability, Studies Assert
Reduced exposure to sunlight, previously reported as a risk factor for developing multiple sclerosis (MS), also seems to increase…
Boosting Cholesterol Recycling in Brain Facilitates Myelin Repair, Study Says
New research in mice suggests that poor recycling of cholesterol in the brain impairs the repair of myelin, the protective…
Restoring Neuregulin-1 beta 1 Protein Levels May Help Halt MS Progression
The levels of a protein called Neuregulin-1 beta 1 (Nrg-1beta1) decline with the onset and progression of multiple sclerosis…
Children With MS Recover Better From Relapses Than Adults, Study Suggests
Despite having more severe first and second relapses, children with relapsing-remitting multiple sclerosis (RRMS) tend to recover better than…
Adolescents With MS Have Lower Levels of Physical Fitness, Study Reports
Adolescents with multiple sclerosis (MS) have lower levels of fitness compared with healthy teenagers of the same age and…
Fewer Pregnancies, Premature Menopause Linked to Early Onset of Progressive MS
Women who have never given birth are more likely to develop early onset of progressive multiple sclerosis, according to…
Progressive MS Focus of EMSP Virtual Meeting Open to All Starting Today
Progressive multiple sclerosis (MS) is the focus of the 2020 virtual European Multiple Sclerosis Platform (EMSP) annual meeting that runs…
Infection With Toxoplasma Gondii Parasite May Protect Against MS, Study Suggests
Note: This story was updated Aug. 17, 2021, to note that T.gondii infection is a risk factor for…
Monitoring Fluctuations in Brain Volume May Help Track RRMS Disease Progression
The brain volume of people with relapsing-remitting multiple sclerosis (RRMS) undergoes a dynamic cycle of enlargement and contractions, a…
Small, Myelin-rich Vesicles May Help Control Immune Response in MS, Animal Study Shows
Extracellular vesicles (EVs), tiny sacs released from myelin-producing cells called oligodendrocytes, may help dampen the immune system’s attack against…
Pathway and Its Proteins Found to Control Myelin Repair, Renewal
A pathway controlled by three proteins — Daam2, Nedd4, and VHL — was identified by researchers as a key regulator of…
MS Patients Should Avoid ‘Silver’ Tooth Fillings Due to Mercury, FDA Advises
People with multiple sclerosis (MS) are among the high-risk groups advised to avoid dental amalgams — silver-colored fillings that are 50%…
Amarna Announces Research Collaboration for Testing MS Gene Therapy Platform
Dutch Amarna Therapeutics announced a research collaboration with Spanish Progreso y Salud Foundation (FPS) to investigate the efficacy of…