News

#ACTRIMS2017 – MS, the Gut and Probiotics

Harold Weiner, MD, believes in using probiotics to help treat multiple sclerosis.Ā He is such a believer that he did a presentation on the subject ā€” “Probiotics in Multiple Sclerosis” ā€” at the just-concluded Americas for Treatment and Research in Multiple Sclerosis (ACTRIMS) 2017 Forum in Orlando. The event…

Full Transcript of Interview with Genentech’s Medical Director, Peter Chin, on Ocrevus

BelowĀ is a transcript of theĀ Multiple Sclerosis News TodayĀ interview with Dr. Peter Chin ā€” principal medical director at Genentech ā€” about the importance of the pending U.S. Food and Drug Administration (FDA) approval of a Biologics Licensing Application (BLA) for Ocrevus (ocrelizumab). An an indepth article on this interview,Ā lookingĀ Ocrevus…

#ACTRIMS2017 – Study Reports Possible Link Between Viral Infections, Vitamin D, and Risk for MS

In a U.S. nationwideĀ case study, a team of researchers found evidence forĀ a potential link between viralĀ infections during childhood, vitamin D deficiency, and the risk of developingĀ multiple sclerosis (MS). The study, ā€œEnvironmental risk factors associated with pediatric MS: The role of remote viral infections and vitamin D revisited,ā€ was recently…

#ACTRIMS2017 – Ocrevus Significantly Decreases Disease Activity in MS Patients, Study Shows

Ocrevus (ocrelizumab), an investigational monoclonal antibody, significantly decreases disease activity in patients with multiple sclerosis (MS), and is associated with a higher proportion of patients reaching no evidence of disease activity (NEDA), according to a new analysis. The study,Ā ā€œNEDA analysis by epoch in patients with relapsing multiple…

#ACTRIMS2017 – Novantrone Lowers Relapse Rates over Long Term, But Carries Cancer Risk

Ten years after completingĀ treatment with Novantrone (mitoxantrone), a chemotherapy drug, multiple sclerosis (MS) patients showed evidence of markedly lowerĀ annualized relapse rates, but the therapy’s effects began to wane after five years, a studyĀ presented atĀ ACTRIMS 2017 ForumĀ reported. The study also assessed howĀ Novantrone affects disease progression in primary and secondary progressive…

#ACTRIMS2017 – 3 Trials Show MS Patients Receiving Ocrevus Had No Elevated Infection Risk

A detailed analysis ofĀ relapsing and primary progressive multiple sclerosis (MS) patients in the three Phase 3 trials of Ocrevus (ocrelizumab) showed that the treatment did not significantly increase their risk of infections ā€” serious or otherwise. Certain infections, including common colds and influenza, were numerically more common among Ocrevus-treated patients,…

#ACTRIMS2017 – Some Fatty Acids in Diet Help, Others Hurt Immune System, Study Reports

Short-chain dietary fatty acids, such as propionate, drive the production of regulatory immune T-cells in patients with multiple sclerosis (MS), while long-chain acids promote T-cells that are involved in inflammatory processes. Since the beneficial fatty acids are safe and can be obtained as over-the-counter dietary supplements, researchers suggest they could…

#ACTRIMS2017 – No Evidence of Progression More Likely Among PPMS Patients on Ocrevus

Genentechā€™s Ocrevus (ocrelizumab) increased the proportion of patients with no evidence of progression (NEP) in the recently concluded ORATORIO Phase 3 clinical trial in patients with primary progressive multiple sclerosis (PPMS). The evaluation of NEPĀ ā€” a combined measure of three disability assessments ā€” was a secondary exploratory endpoint of…

#ACTRIMS2017 – Early MS Evidence Found in Asymptomatic First-degree Relatives of Patients

First-degree relativesĀ of multiple sclerosis (MS) patients may develop asymptomatic disease, suggesting the need to further evaluate family members to develop timely prevention strategies. The study,Ā ā€œInvestigating early evidence of multiple sclerosis in a prospective study of high risk family members,ā€ was presented at the Americas Committee for Treatment and…