News

FDA Invites Comment on Pending Stem Cell Therapy Regulations

The U.S. Food and Drug Administration (FDA) will hold a one-day public hearing on four recent draft guidelines regarding the regulation of human cells, tissues, or cellular or tissue-based products (HCT/Ps). Critics of the proposed regulations warn that they curtail the medical use of autologous cell therapy and biologics, and their future potential…

MS Resistance Traced to a Gene Variant in Colombia

A Colombian study reported finding an increased risk of multiple sclerosis (MS) associated with a particular allele, or gene variant, in a group of patients from the Colombian capital, Bogotá. The study also found a protective allele — HLA-DRB1*14 — that might explain the low rates of MS observed throughout the…

Anti-LINGO-1: All You Need to Know

Recently, Biogen released results from its Phase 2 acute optic neuritis (AON) RENEW trial which tested Anti-LINGO-1. Learn more about this results here. So what is Anti-LINGO-1? According to the MS Society, Anti-LINGO-1 (also known as BIIB033) is a treatment in development by the pharmaceutical company Biogen which is currently…

Vitamin D’s Influence on MS Target of New Study

A team of researchers recently discovered two novel multiple sclerosis (MS)-associated genes that are regulated by vitamin D levels. The study, titled “The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells,” was published in the advanced online section of …

MS Researcher Using £50,000 Donation to Further Research

Dr. Richard Reynolds of Imperial College London spoke of the importance of philanthropy to research during a December 2015 visit from Nigel Furmston, a supporter of multiple sclerosis (MS) research, who came to the Hammersmith Campus to award the scientist and his team £50,000 to continue its work into disease development. Furmston, whose wife Sharon suffers from…

Neuronal Repair in MS May Be Triggered by an Inflammatory Molecule

A new study from The Weizmann Institute of Science, Israel, found that the inflammatory molecule CXCL12 promotes neuronal repair during spontaneous remission in mice with experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis (MS). The chemokine CXCL12 was previously thought to be a pro-inflammatory molecule only. But recent findings have shown…

Potential MS Treatment Targeting CD3 Receptor Moving into Development

Tiziana Life Sciences, plc, a biotechnology company specializing in drugs to treat immunological and oncological diseases,  recently announced its intent to further develop foralumab, a fully human monoclonal antibody targeting the CD3 receptor. This approach, aiming to modulate the immune T cell response and achieve immunosuppression, is well-validated and has the potential to…

Young MS Patients Gain in Functional Connectivity with Onset of Damage to Brain

A Canadian study showed that child-onset multiple sclerosis (MS) is characterized by increased functional connectivity within the brain, most likely a compensatory effect to preserve function and protect against physical disability. The study, titled “Alterations in Functional and Structural Connectivity in Pediatric-Onset Multiple Sclerosis,“ was published in the journal …

MS Patients Treated in Clinical Practice with Fingolimod Show Benefits

New research evaluating fingolimod’s clinical efficacy, safety, and tolerability in patients with relapsing-remitting multiple sclerosis (RRMS) largely supported its use, finding that the oral drug’s efficacy in a real-world setting was comparable to results observed in Phase 3 clinical studies. The research article, “Efficacy and Safety of Fingolimod in an Unselected…

MS Progression Halted Using Stem Cells Derived from Gum Tissue

A new source of stem cells, the mesenchymal stem cells (MSCs) isolated from the human periodontal ligament (hPDLSCs), offers a potential treatment capable of halting multiple sclerosis (MS) progression. The study, “Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis,” was published…

MS Patients and Caregivers Invited to Take Part in Meditation Study

A new randomized and controlled trial is recruiting multiple sclerosis (MS) patients to investigate the effect of a mindfulness-based telemedicine intervention program on patients and their caregivers. The clinical study’s protocol was recently published in the journal Trials, titled “A telemedicine meditation intervention for people with multiple sclerosis…

Rise in MS and Autoimmune Disease Linked to Processed Foods

In a new study, researchers found that additives common to processed foods can damage the tight junctions that protect the intestinal mucosa, and which are essential to the intestinal tolerance and immunity balance that works to prevent autoimmune diseases such as multiple sclerosis (MS). The article, titled “Changes in…

Multiple Sclerosis Association of America Appoints New President and CEO

The Multiple Sclerosis Association of America (MSAA), a national nonprofit organization and leading resource for the multiple sclerosis (MS) community, recently announced that Gina Ross Murdoch has been named the association’s new president and CEO. Ms. Murdoch is now the MSAA’s leader in areas comprising strategic progress, programmatic growth, and business development strategies.

Potential Mechanism in MS Pathogenesis Seen in Study

Researchers found that a group of untreated patients with multiple sclerosis (MS) and patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) carry a specific group of hyperactivated immune cells, the inflammatory CD8+ T cells, suggesting a potential common mechanism contributing to disease pathogenesis. The study, “A Preliminary Comparative…

Volunteer Yoga Instructor Helps Multiple Sclerosis Patients

Gail Pickens-Barger is a doTERRA Elite Wellness Advocate who has been helping students to improve their fitness for 15 years. The yoga instructor is now also dedicated to serving the fitness goals of a particular population — patients with multiple sclerosis (MS). MS is a demyelinating disease in which the insulating layer (called myelin)…

New Study Focuses on Sleep Troubles and Quality of Life in MS Patients

A new study investigated the influence of sleep disturbance, fatigue and disability on the quality of life (QOL) in multiple sclerosis (MS) patients. Health-related QOL measurements are important tools for assessing the impact of a disease on self-reported physical, mental, emotional, and social functioning. Most studies show that QOL is not related to…