News

#CONy16: Scientists Debate MRI’s Role in MS Treatment Changes; Exclusive Interview with Prof. Xavier Montalban

The precision of magnetic resonance imaging (MRI) measurement has improved over the years, and now scans can identify brain damage before symptoms begin showing. Whether the presence of new or expanding lesions predict disease progression is, however, still controversial, and clinicians have no guidance when making treatment decisions about the…

Resistance Training in Ms Patients Found to Improve Hip Strength, Walking Ability

Researchers at the Kennedy Krieger Institute and Johns Hopkins University School of Medicine released preliminary results of an ongoing study into an effective and progressive resistance training program to improve hip strength and walking ability, areas of concern in neurodegenerative diseases like multiple sclerosis (MS). The program, consisting of exercises using resistant…

Blood Biomarkers of Multiple Sclerosis May Predict a Person’s Response to Treatment

Blood biomarkers in individual multiple sclerosis patients may help clinicians determine which treatments would be of most benefit to that person, according to researchers at Oklahoma Medical Research Foundation (OMRF). The study, published in the journal Neurology, Neuroimmunology & Neuroinflammation, is titled “Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients.”…

Virtual Reality Balance Training in RRMS Patients Shows Benefits in Small Study

Interventions to improve balance in patients with multiple sclerosis (MS) have produced varying results, but a small clinical trial showed that balance training using a virtual reality tool could help people with relapsing-remitting MS (RRMS) and might improve adherence to training. Virtual reality tools are a popular training approach, not least because compliance to…

New MS Survey Looks into Patients’ Appraisal of Risks, Benefits When Choosing Therapies

A large-scale online survey, funded by the National Multiple Sclerosis Society  and developed by researchers, is investigating how multiple sclerosis (MS) patients perceive and evaluate the risks and benefits of available therapies. Investigators encourage MS patients to participate in the survey, titled “Multiple Sclerosis Risk Tolerance,” which can be…

Kinase Inhibitor, Masitinib, Spotted for Potential to Treat Neurological Disorders Like PPMS

AB Science recently reported the publication of four peer-reviewed and independent research papers that add to the growing recognition of masitinib, the company’s lead compound, as a promising treatment for neurological and neurodegenerative diseases, including progressive multiple sclerosis (MS), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS). Tyrosine kinase inhibitors (TKIs)…

European Regulatory Agency Finds Gilenya Not of Added Benefit to Certain RRMS Patients

A new assessment by a European regulatory agency failed to find fingolimod of added benefit to comparator therapies for people with highly active relapsing-remitting multiple sclerosis (RRMS) who have failed to respond to treatment with at least one other disease-modifying drug. Fingolimod (Gilenya), developed as a therapy for multiple sclerosis, has undergone three early benefit assessments since its…

Can Playing Video Games Reduce MS-induced ‘Brain Fog’?

Video games targeting cognitive abilities may improve brain function in patients with multiple sclerosis (MS), a new study found. Results, published in the journal Radiology, showed that these games strengthen connections between neurons in the thalamus, a brain region crucial for information processing. The findings also add to…

#MySupportHero Program Celebrates MS Caregivers in All Walks of Life

To celebrate the many family, friends, healthcare professionals, and advocacy communities offering vital support to people living with multiple sclerosis (MS) day after day, MSWorld and Biogen have created the #MySupportHero program. The social media campaign runs through March, MS Awareness Month, to allow people with MS to thank all those who encourage and…

Damage to Nerve Synapses in MS Mouse Model Found to Be Unrelated to Myelin Destruction

Researchers found that nerve cell connections in the brain, called synapses, were damaged in a mouse model of multiple sclerosis (MS) through a process wholly unrelated to myelin destruction. As the damaged mice synapses studied were in regions crucial for memory processing, finding ways of protecting these neurons would be a crucial step toward developing a…

Kessler Foundation MS Researcher Awarded $70,000 Fellowship to Investigate Cognitive Function

Silvana L. Costa, PhD from the Kessler Foundation, was recently awarded a Switzer Research Fellowship by the National Institute on Disability, Independent Living and Rehabilitation Research (NIDILRR). Dr. Costa is a Hearst Fellow in Neuropsychology & Neuroscience Research at Kessler, where she investigates cognitive deficits in multiple sclerosis (MS). The Merit Fellowship,…

Science Foundation Awards to Further Work into Rehabilitative Robotics, Online Tools at Northwestern University

Two scientists at Northwestern University, Anne Marie Piper and Brenna Argall, recently received the Faculty Early Career Development (CAREER) Award from the National Science Foundation (NSF). The work of Dr. Argall, in particular, might be relevant for people with disabilities caused by diseases such as multiple sclerosis or brain trauma resulting from accidents…

Therapeutic Target for Stabilizing Histamine, an Inflammatory Agent in MS, Identified in Fruit Fly Study

Researchers at the University of Massachusetts Medical School, working in the fruit fly model, identified an organic cation transporter, CarT (carcinine transporter), that is crucial to the recycling of histamine in the brain and the maintenance of healthy vision. Histamine is a neurotransmitter involved in chronic inflammation and pathogenesis in multiple…