News

EU funds research consortium seeking causes of MS, treatments

The European Union (EU) is providing 7.1 million euros (about $7.6 million) over five years to a global interdisciplinary consortium that seeks to identify the causes of multiple sclerosis (MS) — with a particular focus on viruses — and find new treatments for the disease. The “BEHIND MS”…

Blood levels of MIF protein may predict brain atrophy with PPMS

Higher blood levels of macrophage migration inhibitory factor (MIF), a molecule involved in inflammation, may predict a faster rate of brain shrinkage, or atrophy, in people with primary progressive multiple sclerosis (PPMS). That’s according to a new analysis of data from the SPRINT-MS Phase 2 trial (NCT01982942) that…

EBV-001 vaccine prevents EBV infection in lab-grown human cells

EBV-001, a vaccine candidate being developed by EBViously to target the Epstein-Barr virus (EBV), triggered the production of potent antibodies against the virus in mice, and blood samples from these animals prevented EBV infection in lab-grown human cells. That’s according to new data presented by the company, which is…

4 new SPMS patients dosed with nasal foralumab outside of trials

Tiziana Life Sciences has dosed four new participants in an expanded access program investigating its foralumab nasal spray in people with nonactive secondary progressive multiple sclerosis (SPMS), the company announced. A total of 10 SPMS patients are now being followed outside of clinical trials in foralumab’s expanded…

FDA clears BrainSpec’s tool to measure metabolites on brain scans

The U.S. Food and Drug Administration (FDA) has cleared BrainSpec Core, a platform that performs non-invasive measurements of brain chemistry, for use in diagnosing some of the most common diseases that affect the brain, including multiple sclerosis (MS). Developed by BrainSpec, the platform uses magnetic resonance spectroscopy (MRS)…

Sedentary behaviors more common among MS patients: 11 studies

People with multiple sclerosis (MS) engage in significantly more sedentary behaviors — activities like watching TV or using a computer or smartphone versus those requiring physical movement, such as exercise — than do individuals without the progressive disease, according to a pooled analysis of published studies. This effect was…

Stem cell therapy well tolerated in SPMS clinical trial

A novel therapy in which neural stem cells are injected into the brain was well tolerated by 15 people with secondary progressive multiple sclerosis (SPMS) in a pilot clinical trial. Participants’ disability levels and cognition, as well as markers of inflammation and nerve damage, all remained stable for up…

Providers weigh treatment logistics in selecting DMTs for MS patients

Certain clinical attributes of disease-modifying therapies (DMTs), such as safety and the medication’s impact on risk of relapse and disability progression, are considered important by healthcare providers in selecting the appropriate treatment for people with multiple sclerosis (MS), according to a new survey study. However, a study experiment also…

Extending Tysabri dose intervals controls RRMS activity

Extending Tysabri (natalizumab) dosing intervals based on the drug’s blood levels was as effective at controlling disease activity in people with relapsing-remitting multiple sclerosis (RRMS) as the approved four-week dosing regimen. That’s according to results from NEXT-MS (NCT04225312), a Phase 4 clinical trial studying whether tailoring Tysabri’s…

FDA clears AI tool for detecting disease activity on MRI scans

Pixyl.Neuro, a next-generation software that uses artificial intelligence (AI) in analyzing MRI scans to help detect and monitor multiple sclerosis (MS) disease activity, has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for clinical use. 510(k) clearance is required for medical devices used in the…

Hackensack Meridian’s status as comprehensive care center renewed

The National Multiple Sclerosis Society (NMSS) again has certified Hackensack Meridian Neuroscience Institute’s Center for Multiple Sclerosis and Related Diseases at Hackensack University Medical Center as a multiple sclerosis (MS) comprehensive care center. In addition to meeting the NMSS’ core requirements, the certification’s renewal also recognizes…

Supplementation with coconut oil, green tea may help reduce triglycerides

Supplementation with coconut oil and the green tea component epigallocatechin gallate (EGCG) significantly reduces the levels of fatty molecules called triglycerides in people with multiple sclerosis (MS), according to a pilot study from Spain. This reduction may complement improvements in functional capacity that have been reported previously following…