February 13, 2023 News by Margarida Maia, PhD Dietitian advice assists MS patients to improve calcium intake: Trial A tailored diet plan from a dietitian may help people with multiple sclerosis (MS) ingest more calcium from foods, which could make their bones stronger and less prone to osteoporosis. That’s according to data from CalciCoach (NCT02664623), a clinical study that compared the amount of dietary calcium consumed…
March 11, 2021 News by Margarida Maia, PhD Vitamin D Supplements at Preclinical Stage Prevented MS in Mice Vitamin D, but not paricalcitol (a vitamin D analog), can be used as a preventive measure to control the severity of multiple sclerosis (MS), according to a new study of mice. The study, “Preclinical therapy with vitamin D3 in experimental encephalomyelitis: Efficacy and comparison with paricalcitol,” was…
January 27, 2021 News by Marta Figueiredo, PhD Mouse Study Links Cortical Inflammation to Immune Cell Destruction Multiple sclerosis (MS)-associated inflammation in the cerebral cortex — the outermost layer of the brain that is involved in cognitive function — prompts the destruction of neural connections by specific immune cells, according to a study in a mouse model of MS. These immune cells targeted dendritic spines (nerve…
March 2, 2020 News by Ana Pena PhD #ACTRIMS2020 – Vitamin D at High Dose Can Worsen MS, Early Study Says High-dose vitamin D supplements appear to aggravate inflammation and myelin loss in the brain and spinal cord, and worsen the disability associated with multiple sclerosis (MS), a study in a mouse disease model reported. Excessive use of vitamin D causes calcium levels to…
January 28, 2019 News by Jose Marques Lopes, PhD Tiny Cell Membrane Disruptions Lead to Nerve Fiber Degeneration in MS, Mouse Study Suggests Tiny ruptures in the cell membrane of nerve fibers enable the entry of calcium and ultimately lead to their degeneration, a study in a mouse model of multiple sclerosis (MS) suggests. The study, “Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple…
April 4, 2018 Columns by Judy Lynn 2 Great Things that Go Great Together: Calcium and Magnesium While Reese’s Peanut Butter Cups are the true “two great things that go great together,” calcium and magnesium take first place for those with MS. Many proponents of special diets for MS encourage the consumption of foods high in this mineral dynamic duo (along with other vitamins needed for…
March 28, 2017 News by Joana Fernandes, PhD Increased Rab32 Protein Levels May Be Involved in MS Progression, Canadian Study Finds High levels of a protein called Rab32 may contribute to the progression of multiple sclerosis (MS), leading to neuronal loss, a new study concludes. The study, “Rab32 connects ER stress to mitochondrial defects in multiple sclerosis,” appeared in the Journal of Neuroinflammation. The endoplasmic reticulum (ER) is involved in the production…
