February 1, 2023 News by Marisa Wexler, MS Hi-res MRI Scanners May Bring MS’s Effect on the Cerebellum Into View Researchers were able to image the cerebellum ā a small, compact region of the brain that plays key roles in multiple sclerosis (MS) and other diseases ā with greater clarity than ever before. Their imaging approach, which used MRI scanners equipped with powerful magnets, may help learn how…
November 16, 2021 News by Patricia Inacio, PhD Cerebellar Lesions in RRMS Linked to Worsening Manual Dexterity The number of lesions affecting the cerebellum ā a brain region responsible for coordinating voluntary movements and motor skills such as balance, coordination, and posture ā predicts manual dexterity getting worse in people with relapsing-remitting multiple sclerosis (RRMS), according to a retrospective analysis. The study, āCerebellar pathology and…
May 31, 2019 News by Jose Marques Lopes, PhD Abnormal Activation of Neutrophils a Potential Therapeutic Target in MS, Mouse Study Suggests Targeting the excessive activation of immune cells called neutrophils, and the associated oxidative stress, may be a therapeutic strategy in patients with multiple sclerosis (MS), according to a mouse study. TheĀ study, āDeficiency of Socs3 leads to brain-targeted EAE via enhanced neutrophil activation and ROS production,ā was…
September 21, 2018 Columns by Jamie Hughes What the Scan Said (and What It Didn’t) A couple weeks ago, I went to my neurologistās office early for my annual MRI. Itās never a pleasant experience. Even after 14 years, itās still as unsettling as it was the first time. Itās not the tightness of the space that gets me or the sensations and sounds.
December 14, 2016 News by Joana Fernandes, PhD Gadolinium, an MRI Contrast Agent That Accumulates in Brain, May Contribute to MS Certain contrast agents used during magnetic resonance imaging (MRI) may accumulate in specific brain areas and contribute to disease duration and severity in patients with multiple sclerosis (MS), according to a new study published in the Multiple Sclerosis Journal. The study, “Gadopentetate But Not Gadobutrol Accumulates In The…
December 9, 2016 News by Patricia Silva, PhD Key Myelin Protein, MBP, Seen to Break Down Differently in Brains of MS Patients ResearchersĀ monitoring the decomposition of an abundant brain protein, called myelin basic protein (MBP), discovered that this protein breaks down differently in people withĀ multiple sclerosis (MS) than it does in those without the disease, particularly in two surface regions, and that difference may be the trigger for immune reactions and myelin…
December 7, 2016 News by Patricia Inacio, PhD Lower Oxygen in Brain’s Gray Matter Linked to More Impairment in Mouse Study The less oxygen that a mouse withĀ multiple sclerosis (MS) has in the gray matter of itsĀ brain, the more mental and physical deterioration it isĀ likely to have, a new study suggests. The study confirms previous research indicating a connection between low oxygen levels in a mouse’s gray matter and the development…
October 14, 2016 News by Patricia Silva, PhD Regular Exercise Found to Repair Damage to Neurons in Brains of Mice Voluntary running triggers a molecule called VGF, a nerve growth factor,Ā that was seen to induce a brain repair mechanism in animals, researchers at The Ottawa Hospital and the University of Ottawa in Canada report. The findings have important implications for multiple sclerosis (MS) and other conditions caused by damage to…
March 28, 2016 News by admin MS Lesions in Cerebellum Ably Predict Disability Levels and Disease Progression, Study Suggests DamageĀ toĀ the cerebellum in people with multiple sclerosis (MS) is due moreĀ to the death of actual nerve cellsĀ thanĀ the destruction of white matter connections, a new study out of Italy suggests. The article, which challenges previous ideas about how brain damage in MSĀ occurs, is titledĀ “MRI-detectable cortical lesions in the…