November 18, 2022 News by Marisa Wexler, MS Effect of Diabetes Medicines on MS Risk Varies by Age, Sex in US Study Among people with type 2 diabetes, the use of anti-hyperglycemic medications is associated with a reduced risk of multiple sclerosis (MS) for younger individuals, but an increased risk for older patients, particularly women. That’s according to the study āAge and sex differences on anti-hyperglycemic medication…
June 24, 2022 News by Margarida Maia, PhD Uncontrolled Hypertension More Likely in Black Americans With MS Black Americans with multiple sclerosis (MS) have a higher chance of having uncontrolled high blood pressure (hypertension), despite being more likely to receive anti-hypertensive medication than white patients, a large study found. Further studies are needed to confirm these findings and…
August 5, 2021 News by Marisa Wexler, MS Metformin Seen to Aid Cognition, Brain Biology in MS Rat Model Treatment with the diabetes medication metformin was seen to lessen cognitive impairment, improve coordination, and normalize neuronal activity in a rat model of multiple sclerosis (MS). The study reporting these findings,Ā “Evaluation of the effects of metformin as adenosine monophosphate-activated protein kinase activator on spatial learning and…
December 31, 2020 News by Diana Campelo Delgado MS Risk May Be Higher for Children of Diabetic Mothers, Study Suggests Children of diabetic mothers may be at more risk of developing multiple sclerosisĀ (MS), a Danish national study suggests. The study, āMaternal diabetes and risk of multiple sclerosis in the offspring: A Danish nationwide register-based cohort study,ā was published in theĀ Multiple Sclerosis Journal. Previous studies have suggested a…
September 29, 2020 News by Patricia Inacio, PhD Amarna Announces Research Collaboration for Testing MS Gene Therapy Platform Dutch Amarna Therapeutics announced a research collaboration with Spanish Progreso y Salud Foundation (FPS) to investigate theĀ efficacy of its gene therapy delivery technology in multiple sclerosis (MS) and diabetes. MS is thought to be caused by immune-mediated inflammation that damages myelin ā an insulating sheath around nerve…
September 14, 2020 News by Marta Figueiredo, PhD #MSVirtual2020 – Cardiovascular Risk Factors Linked to Brain Shrinkage In people with multiple sclerosis (MS) under age 50, the presence of cardiovascular risk factors is associated with a greater loss of brain volume, including white and grey matter, a study showed. The brainās white matter mainly consists of nerve fibers and is typically affected by MS, while…
October 14, 2019 News by Marisa Wexler, MS Metformin Works to Promote Remyelination in Ways Similar to Fasting, Study Says Metformin, a common diabetes treatment that works to mimic dietary fasting, was seen to promote remyelination in the stem cells of elderly rats, suggesting it may be useful in treating multiple sclerosis. “Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells” was published in…
September 11, 2019 News by Patricia Inacio, PhD #ECTRIMS2019 – Real-world Data Supports Serum Neurofilament Light as Potential MS Biomarker Serum neurofilament light chain (sNfL) in the blood ā a proposed biomarker for multiple sclerosis (MS) ā is linked with worse neurologic function at levels above a certain threshold, according to data from a large, real-world study. Kathryn Fitzgerald, assistant professor at the Johns Hopkins School of…
August 22, 2019 News by Alejandra Viviescas, PhD Gene on X Chromosome May Be Reason Women at Higher Risk of MS, Study Says Females of certain species ā like humans and mice ā have a known ability to produce more of the geneĀ Kdm6aĀ than males because it’s located on the X chromosome, of which females have two.Ā Kdm6aĀ is also quite active in immune system T-cells, a study found, and silencingĀ it in a mice model…
November 6, 2018 News by Patricia Inacio, PhD Diabetes, Hypertension, Smoking Linked with Brain Shrinkage in MS Patients Diabetes, hypertension, and active smoking correlate with more brain shrinkage in multiple sclerosis (MS) patients, a new study shows. The study, āAssessing the burden of vascular risk factors on brain atrophy in multiple sclerosis: A case- control MRI studyā was published in the journalĀ Multiple Sclerosis and Related Disorders.
December 1, 2016 News by Patricia Silva, PhD Protein from Parasite Lowers Relapse Rates, Evidence of Demyelination in Mice with MS A moleculeĀ secreted by a parasite was seen to prevent autoimmune reactionsĀ in a mouse model of multiple sclerosis (MS). As this molecule, a protein factor or peptide, also worked to preventĀ diabetes, researchers suggestĀ it might be developed intoĀ aĀ potential treatment for autoimmune diseases. The study, “A parasite-derived 68-mer peptide ameliorates…