OPCs

Proteins Called Tenascins Found to Block Myelin Repair in Mouse Model

Proteins called tenascins block the regeneration of myelin by modulating the activity of oligodendrocytes, myelin-making cells of the central nervous system, a study in mouse modelsĀ indicates. “Our research results open up new therapeutic approaches for the treatment of demyelinating diseases such as multiple sclerosis,” Juliane Bauch, a researcher at Ruhr-University…

#ACTRIMS2021 – Young Brain Fluid (CSF) Rejuvenates Memory in Mice

Editorā€™s note: TheĀ Multiple Sclerosis News Today news team is providing in-depth and unparalleled coverage of the virtual ACTRIMS Forum 2021, Feb. 25-27. GoĀ hereĀ to see all the latest stories from the conference. Factors in the cerebrospinal fluid (CSF) surrounding the brain and spinal cord change with age and can affect…

Potential Therapy, Anavex 2-73, Shows Ability to Protect Neurons and Promote Myelin in Early Tests

Anavex Life Sciences‘ investigational therapy Anavex 2-73 (blarcamesine) showed an ability to protect, repair, and induce the formation of oligodendrocytes ā€” the cells that produce the protective myelin layer around neurons ā€” in early cell testing, researchers reported. These findings, which further establish the therapy’s potential as a treatment…

Blocking LRP1 May Halt Inflammation, Promote Remyelination, Mouse Study Suggests

Blocking production of the low-density lipoprotein receptor-related protein 1 (LRP1) ā€” involved in inflammatory and immune responses ā€” specifically in myelinĀ repair cells halts neuroinflammation and promotes myelin repair, a preclinical study shows. These results, fromĀ two mouse models of multiple sclerosis (MS), shed light on the underlying mechanisms…

Experimental MS Therapy Seen to Promote Myelin Regeneration in Preclinical Study

RegeneRx Biopharmaceuticals, Inc.,Ā announced the publication of a research article detailing the process by whichĀ Thymosin beta 4 (TĪ²4), the company’s novel therapeutic peptide, effectively promoted the remyelination process in two separate animal models commonly used for multiple sclerosis (MS) research. The article, ā€œThymosin beta4 promotes oligodendrogenesis in the demyelinating…