January 29, 2024 News by Andrea Lobo, PhD Gender, age at PPMS onset has no impact on disability progression Gender and age at the onset of disease don’t seem to have a clinically relevant impact on disability progression in people with primary progressive multiple sclerosis (PPMS), according to a recent study in Argentina. Disease progression, based on the Expanded Disability Status…
August 22, 2023 News by Patricia Inacio, PhD Progressive MS trial of vidofludimus calciumĀ fully enrolled A global Phase 2 clinical trial investigating theĀ oral therapy vidofludimus calcium (IMU-838) in people with progressive forms of multiple sclerosis (MS) has reached full enrollment, the treatment’s developer, Immunic Therapeutics, reports. Called CALLIPER (NCT05054140), the trial is assessing whether the neuroprotective effects of vidofludimus calciumĀ seen in…
January 12, 2022 News by Yedida Y Bogachkov PhD Cognitive Dysfunction Found to Increase Risk of Death in MS Cognitive dysfunction in patients with multiple sclerosis (MS) is predictive of worse outcomes, including clinical progression of the disease and a higher risk of mortality, according to a new study. “This review revealed that cognitive dysfunction … was associated with higher odds of transitioning from [a] relapsingāremitting course to…
March 4, 2019 Columns by Ed Tobias MS News that Caught My Eye Last Week: New DMT, Stem Cell Trial, Pediatric MS Treatment Study FDA Will Review New Drug Application of Diroximel Fumarate for Relapsing Forms of MS The good news: Another disease-modifying therapy (DMT) has taken a step toward approval in the U.S. The discouraging news: It’s another DMT designed to treat relapsing forms of multiple sclerosis. More than a…
April 2, 2018 Columns by Debi Wilson What It’s Like Constantly Living with Primary Progressive MS My column last week was a recap of my journey to a primary progressive multiple sclerosis (PPMS) diagnosis. This week’s column continues that theme by showing a glimpse of what it is like to live with PPMS on a daily basis. To say that having a disability like…
March 26, 2018 Columns by Debi Wilson My Unique Primary Progressive MS Diagnosis I have lived with the diagnosis of primary progressive multiple sclerosis (PPMS)Ā for almost eight years. For many years prior to that diagnosis, I was confused by what could be causing my abnormal gait, extreme fatigue, blurred vision,Ā and trouble concentrating. During that time, I completed many diagnostic tests, dealt…
January 7, 2016 News by Patricia Silva, PhD MS Drug Under Study No Longer Being Given in Higher Doses to Patients Teva Pharmaceutical Industries Ltd. and Active Biotech have discontinued the use of higher doses of the drug laquinimod in two ongoing multiple sclerosis (MS) studies. The decision was based on a recommendation byĀ the Data Monitoring Committee (DMC)Ā that isĀ supervising the clinical trials afterĀ cardiovascular events, none of which were fatal,…