June 17, 2022 News by Mary Chapman Innovative Trials, MS Society UK Collaborate on MS Research Innovative Trials has selected the MS Society UK as its charity partner for the next year, and intends to raise at least Ā£3,000 (about $3,600) to support multiple sclerosis (MS) research and the society’s quest for a world without MS. Innovative Trials works with pharmaceutical companies and…
January 3, 2022 Columns by Ed Tobias MS News That Caught My Eye Last Week: Cortrophin Gel, Simvastatin, COVID-19 Treatments Cortrophin Gel Now Available in US at AllianceRx Walgreens Prime Cortrophin Gel is similar to Achtar Gel, which was, until the U.S. Food and Drug Administration’s recent re-approval of Cortrophin, the only repository corticotropin injection available in the U.S. Cortrophin Gel is a naturally produced cortisol that is expected…
December 23, 2021 News by Marisa Wexler, MS Results From Trial of Simvastatin for SPMS Expected in 2025 MS-STAT2, a clinical trial testing whether the cholesterol-lowering medication simvastatin might slow disability progression in secondary progressive multiple sclerosis (SPMS), has finished enrollment. A total of 964 people are now in the trial (NCT03387670), making it the largest progressive MS trial not run by a commercial…
May 22, 2019 News by Joana Carvalho, PhD Simvastatin, Common Statin, Treats SPMS in Ways Distinct from Cholesterol, Study Suggests Simvastatin, a widely prescribed statin that works to lower cholesterolĀ levels, may slow brain atrophy and disease progression in people with secondary progressive multiple sclerosis (SPMS) for reasons unrelated to changes in blood cholesterol, a new analysis of a Phase 2 clinical trial reports. These findings are in…
September 14, 2018 News by Diogo Pinto Phase 3 Trial in UK Soon to Test Statin, Simvastatin, in Slowing SPMS Progression A large Phase 3 trial getting underway at sites across the U.K. willĀ test the effectiveness of simvastatin, a widely used oral statin, in possibly treating secondary progressive multiple sclerosis (SPMS), the study’s sponsor,Ā University College of London Hospitals (UCLH), announced. The study, the largest ever undertaken for SPMS…
June 8, 2017 News by Patricia Silva, PhD High-dose Simvastatin Improves Cognitive Function in MS, New Analysis of Trial Results Reports A high daily dose of simvastatinĀ improves multiple sclerosis patients’ cognitive function, according to a new analysis of Phase 2 clinical trial results. The British team that did the research will start a study soon on whether simvastatin, which goes by the brand name ZocorĀ and other labels, can also slow…
May 15, 2017 Columns by Ed Tobias MS News That Caught My Eye: Ocrevus Q&A, Cheap SPMS Therapy in Testing, and New Research In case you missedĀ them, here are some news stories that appeared in MS News Today that caught my eye over the past week. MSAAās Dr. Jack Burks Responds to Readersā Questions About Ocrevus and Its Use All over the internet MS patients are asking questions about…
May 12, 2017 Columns by Ed Tobias Cholesterol Medication Shows Promise as MS Treatment I’ve been taking a statin drug for years to keep my cholesterol low, and it’s doing a really good job. Now, there’s hope that this class of drug also might be useful for MS patients. A major trial in the U.K. is testing the drug simvastatin (used to control…
May 11, 2017 News by Joana Fernandes, PhD NMSS, British Partners to Launch Phase 3 Trial to Determine Efficacy of Simvastatin in SPMS Patients The National Multiple Sclerosis SocietyĀ (NMSS), together with its British partners, plans to launchĀ a Phase 3 trial in the next few months to investigate whether simvastatin ā a cheap drug that controls cholesterol levels ā may be a suitable treatment for people with secondary progressive multiple sclerosis (SPMS). The trial,…
July 18, 2016 Columns by admin MS Patientās Pick of the Weekās News: Remyelination Drug Patent, Gut Microbiota, Statins, Cognition and Depression Quite a mixed bag in theĀ pick of the week’sĀ news: A drug in development, microbiota in the gut, statins and MS, DMTs and cognitive skills, and images of depression. Endece Granted New U.S. Patent for NDC-1308, Therapy to Induce Remyelination in MS This is a bit of an…
July 11, 2016 News by Patricia Silva, PhD Workings of Common Statin, Simvastatin, Explored in Ways Relevant to Multiple Sclerosis One of the worldās most commonly used medications ā the cholesterol-lowering drug simvastatin ā was found to affect the immune system in a way that can be explored to treat inflammatory diseases such as multiple sclerosis (MS). Researchers have earlier noted that simvastatin, a cholesterol-lowering drug, is beneficial for MS…
November 20, 2015 News by Patricia Silva, PhD MS Society Funds 5 Projects Aiming to Cure the Disease The Multiple Sclerosis Society (MS Society) in the United Kingdom recently announced the investment of Ā£1.98 million in new MS research. After an in-depth, rigorous review process of the 58 applications submitted, 16 projects were awarded funding through the MS Societyās 2015 grant round totaling Ā£1,979,879. All applications…