supplements

Increasing blood vitamin D levels with high-dose supplementation can significantly reduce the risk of new disease activity in people with clinically isolated syndrome (CIS), or those who experienced a first episode of symptoms suggestive of multiple sclerosis (MS). That’s according to new data from the D-Lay-MS…

High doses of vitamin D provide clinically modest but statistically significant benefits for adults with multiple sclerosis (MS), according to a meta-analysis of published clinical trials. The study found patients who took the supplement saw reductions in disability scores, relapses, and new lesion formation. Those who took vitamin D for…

Three months of daily supplements containing ellagic acid — an antioxidant found naturally in many fruits and plants — significantly reduced disability levels and eased fatigue, depression, and anxiety in people with multiple sclerosis (MS), according to a small clinical study from Iran. Indeed, the researchers noted a “statistically…

A high dose cholecalciferol, a form of vitamin D, significantly reduced the risk of further disease activity in people with clinically isolated syndrome (CIS), published findings from a Phase 3 trial show. Vitamin D was similarly effective for reducing disease activity among a subgroup of participants who would…

Higher blood levels of bile acids — molecules found in the digestive fluid bile, which helps absorb fat in the gut — are associated with a slower progression of multiple sclerosis (MS), as indicated by imaging scans, a study by U.S. researchers reported. In a small clinical trial in…

Taking high-dose cholecalciferol (vitamin D) as a supplement is safe and can nearly double the time it takes for people with clinically isolated syndrome (CIS), a first manifestation of neurological symptoms suggestive of multiple sclerosis (MS), to experience new disease activity. That’s according to data from D-Lay-MS…

Supplements of indole 3-lactate (ILA), a molecule made by gut bacteria, significantly reduced disease severity and promoted myelin repair in mouse models of multiple sclerosis (MS). That’s according to new findings presented by Larissa Jank, PhD, a postdoctoral researcher at Johns Hopkins University, at the Americas Committee for Treatment…

Taking melatonin before bedtime may help balance and muscle strength in people living with multiple sclerosis (MS), according to a study from Tunisia. Those benefits are in addition to making for more restful sleep. While the findings come from a small number of patients, they suggest melatonin supplements may…

Taking a two-month supplement of crocin, an antioxidant found in the cooking spice saffron, helped to reduce signs of inflammation in people with multiple sclerosis (MS) who took part in a small study in Iran. However, crocin had no effect on symptoms of depression or anxiety compared with a…

Supplementation with coconut oil and the green tea component epigallocatechin gallate (EGCG) significantly reduces the levels of fatty molecules called triglycerides in people with multiple sclerosis (MS), according to a pilot study from Spain. This reduction may complement improvements in functional capacity that have been reported previously following…

Combining a saffron supplement and an exercise program for three months was seen to significantly ease depression and improve quality of life for women with multiple sclerosis (MS), a study in Iran found. The combination of the two treatments worked better than either approach alone. “Although … the corrective…

Taking supplements of the sugar molecule N-acetylglucosamine, known as GlcNAc, was found to decrease markers of inflammation in people with multiple sclerosis (MS) in a small clinical trial. Moreover, nearly a third of trial participants reported less severe disability following a month of daily GlcNAc supplements. However, because this…

An anti-inflammatory diet combined with synbiotic supplements eased fatigue, pain, sexual dysfunction, and bladder and bowel problems in people with progressive forms of multiple sclerosis (MS) in a small clinical trial. Synbiotics contain probiotics, healthy bacteria for the gut, and prebiotics, or plant fibers that feed probiotics and help…

Vitamin D reduced the signs of inflammation and nerve damage in a rat model of progressive multiple sclerosis (MS), a study shows. Low levels of the vitamin have been extensively linked with a higher risk of developing relapsing forms of the disease, but studies of vitamin D supplementation in…

Supplements with tauroursodeoxycholic acid (TUDCA) were generally well tolerated among people with progressive forms of multiple sclerosis (MS), according to findings from a small clinical trial. Results also showed that patients given TUDCA supplements had lower levels of certain inflammatory immune cells than those given a placebo, but no…

A high-dose vitamin D supplement did not reduce the risk of relapses in people with relapsing-remitting multiple sclerosis (RRMS) already using a disease-modifying therapy to control disease activity, according to findings of a Phase 3 clinical trial. The VIDAMS study (NCT01490502) — standing for Vitamin D…

Taking high-dose vitamin D supplements as an add-on to standard MS treatment doesn’t reduce the risk of inflammatory disease activity for people with relapsing-remitting multiple sclerosis (RRMS), according to data from a clinical trial. The findings “suggest that prescribing higher doses of vitamin D for purposes of…

Supplementation with coconut oil and epigallocatechin gallate (EGCG), a green tea extract, in combination with a Mediterranean-style diet, was associated with improvements in balance and gait in people with multiple sclerosis (MS). Those were the findings of a small pilot study in Spain, which also found that all participants,…

Researchers in Iran are conducting a clinical trial to test the effects of taking ginger supplements for people with relapsing-remitting multiple sclerosis (RRMS). Ginger extracts have shown some promise in animal models of multiple sclerosis (MS), but no trial has yet determined the impact that ginger supplements may…

Daily use of MS14, a natural product derived from Persian medicine, safely led to gains in physical activity and walking for people with multiple sclerosis (MS) with walking difficulties, according to data from a small placebo-controlled trial. MS14, which contains both herbal and marine ingredients, “could be used as…

A dietary supplement called Neuroaspis plp10 significantly lowered relapse rates and slowed disability progression among people with relapsing-remitting multiple sclerosis (RRMS) on interferon beta medications, according to a small clinical trial in Greece. “The results of this study suggest that Neuroaspis plp10 may offer greater benefit to patients with RRMS…

Guar gum, a type of dietary fiber that can be taken as a supplement, lessened inflammation and disease severity in a mouse model of multiple sclerosis (MS), a new study reports. While fiber-rich diets have long been recommended to improve overall health, these findings help pinpoint which fibers have…

Stem Cell Transplant Found to Reduce MS Relapses, Ease Disability This is excellent news for those of us who would like to see stem cell transplant for MS become more available and affordable. These researchers analyzed 50 studies covering a total of 4,831 people with MS, ages 26 to…

People with multiple sclerosis (MS) have significantly higher and potentially damaging blood levels of zinc and a greater activity of the superoxide dismutase (SOD) enzyme than is evident in people without MS or similar diseases, a study reported. SOD is an enzyme that requires zinc to function properly, including…

Roll up, roll up, for all the fun of the fare! I swallow an awful lot of supplements. Have I also swallowed the barkers’ patter? I don’t think so. But I’m more than aware that if something works on mice, then the chances of it working on me are likely…

I’ve been popping vitamin D pills for years — decades, really. I never really understood why, I just knew that many people with multiple sclerosis (MS) are vitamin D-deficient. A recent study has cast some new light on why I should continue. It all seems to comes down to…

Vitamin D can influence the immune system’s tolerance to certain proteins by changing how DNA is packaged in specific immune cells called dendritic cells, according to a new study. Its findings could have implications for treating diseases like multiple sclerosis (MS) that are characterized by the immune system attacking…

Vitamin D supplementation may improve quality of life in people with multiple sclerosis (MS), according to a literature review study. Because vitamin D deficiency is common in MS patients, these findings suggest that “supplementation should be applied at least in a dose that covers the recommended intake,” the researchers…

In this installment of our “Expert Voices” series, Multiple Sclerosis News Today asked registered dietitian Mona Bostick to answer some of your questions related to diet and nutrition for people with multiple sclerosis (MS). Bostick, who has MS, works in private practice in Greensboro, North Carolina, where she helps…

Vitamin D Deficiency Linked to Early Cognitive Issues in Study I’ve taken a vitamin D supplement for many years because numerous studies have shown a correlation between low vitamin D levels and MS. My levels have been normal for years, and I assume the supplement has helped. Even so,…