A $2.5 million donation from the Simon Family Trust is supporting the creation of a new center of expertise to help in the development of new therapies for multiple sclerosis (MS) and other neurological diseases. The new center is being launched by researchers from Gladstone Institutes and the…

A particular type of gut microbiota-reactive immune cells, called IgA-producing B-cells, travels to the brain of multiple sclerosis (MS) patients during relapses, where they produce anti-inflammatory molecules, a study shows. The underlying mechanisms of this event and these cells’ role in MS remain largely unclear, but these…

Immune B-cells are more abundant and have a pro-inflammatory profile in the cerebrospinal fluid (CSF), the fluid that bathes the central nervous system,  compared to blood in people with relapsing-remitting multiple sclerosis (RRMS), a study reports. The results suggest that therapeutic strategies targeting the CSF B-cells could constitute a…

A study suggests that it may be possible to create synthetic speech based on recordings of brain activity in people with irreversible speech loss due to neurological ills, such as multiple sclerosis (MS), Parkinson’s, or stroke. The system uses tiny electrodes implanted on the surface of the brain that directly records…

Scientists have been trying to find a way to restore a protective covering around nerve cells whose loss leads to the neuron damage associated with multiple sclerosis. A team at the University of California, San Francisco may have found a way to do it. And perhaps surprisingly, the possible solution…

University of California medical school researchers are looking for multiple sclerosis patients who want to participate in an international study of the bacteria that live in our gut. The University of California at San Francisco team decided to study the gut microbiome after recent evidence suggested that it is critical in…

Dr. Stephen Hauser, chair of the neurology department at the University of California San Francisco, was instrumental in the early research and later clinical trials that ultimately led to Ocrevus (ocrelizumab), the first therapy approved by the U.S. Food and Drug Administration (FDA) for both relapsing MS (RMS) and primary progressive multiple sclerosis…

Sutter Health, a not-for-profit healthcare network serving more than 100 northern California communities, has been awarded $1.2 million by the California Initiative to Advance Precision Medicine (CIAPM) to support patients living with multiple sclerosis (MS) and help improve how health matters are targeted and treated across the entire state.

Katerina Akassoglou, PhD, a Gladstone Institutes senior investigator, has been awarded a multiyear, $5.8 million career grant from the National Institute of Neurological Disorders and Stroke (NINDS) for her work on neurological diseases, including multiple sclerosis (MS). The Gladstone Institutes is a nonprofit community of scientists, affiliated with the…

The Patient-Centered Outcomes Research Institute (PCORI) recently awarded a sum of $5.5 million to two researchers at the University of California, San Francisco (UCSF). Bardia Nourbakhsh, MD. (Credit: UCSF) Bardia Nourbakhsh, MD, a clinical fellow in Neurology, received a $2 million grant to conduct a randomized, double-blind, placebo-controlled clinical trial to…