February 3, 2021 News by Teresa Carvalho, MS New Center to Advance Research on MS, Neurovascular Disorders A $2.5 million donation from the Simon Family Trust is supporting the creation of a new center of expertise to help in the development of new therapies for multiple sclerosis (MS) and other neurological diseases. The new center is being launched by researchers from Gladstone Institutes and the…
November 25, 2020 News by Marta Figueiredo, PhD Gut Immune Cells That Travel to Brain May Help Resolve MS Disease Relapses A particular type of gut microbiota-reactive immune cells, called IgA-producing B-cells, travels to the brain of multiple sclerosis (MS) patients during relapses, where they produce anti-inflammatory molecules, a study shows. The underlying mechanisms of this event and these cellsā role in MS remain largely unclear, but these…
September 3, 2020 News by Patricia Inacio, PhD Targeting B-cells in Cerebrospinal Fluid May Lead to More Effective MS Therapies, Study Suggests Immune B-cellsĀ are more abundant and have a pro-inflammatory profile in the cerebrospinal fluid (CSF), the fluid that bathes the central nervous system, Ā compared to blood in people with relapsing-remitting multiple sclerosis (RRMS), a study reports. The results suggest that therapeutic strategies targeting the CSF B-cells could constitute a…
April 29, 2019 News by Alberto Molano, PhD Machine System Based on Brain Activity May Restore Speech to Those Who Lost It, Study Reports A study suggests that it may be possible to create synthetic speech based on recordings of brain activity in people with irreversible speech loss due to neurological ills, such as multiple sclerosis (MS), Parkinson’s, or stroke. The system uses tiny electrodes implanted on the surface of the brain thatĀ directly records…
October 13, 2017 News by Patricia Silva, PhD Common Allergy Treatment Restores Protective Neuron Coating in MS, Trial Suggests Scientists have been trying to find a way to restore a protective covering around nerve cells whose loss leads to the neuron damage associated with multiple sclerosis. A team at the University of California, San FranciscoĀ may have found a way to do it. And perhaps surprisingly, the possible solution…
August 11, 2017 News by Patricia Silva, PhD University of California at San Francisco Recruiting MS Patients for Gut Bacteria Study University of California medical school researchersĀ are looking for multiple sclerosisĀ patients who want to participate in an international study of the bacteria that live in our gut. The University of California at San FranciscoĀ team decided to study the gut microbiome after recent evidence suggested that it is critical in…
April 5, 2017 News by Joana Fernandes, PhD UCSF Neurologist Played Key Role in MS Research Turning to B-Cells, Essential Step to Ocrevus Dr. Stephen Hauser, chair of the neurology department at the University of California San Francisco, was instrumental in the early research and laterĀ clinical trials that ultimately led toĀ Ocrevus (ocrelizumab), the first therapyĀ approved by the U.S. Food and Drug Administration (FDA)Ā for bothĀ relapsing MSĀ (RMS) and primary progressive multiple sclerosis…
November 28, 2016 News by Charles Moore Partnership Receives $1.2M from California Initiative to Advance Precision Medicine for MS Sutter Health, a not-for-profit healthcare network serving more than 100 northern California communities, has been awarded $1.2 million by theĀ California Initiative to Advance Precision MedicineĀ (CIAPM) to support patients living with multiple sclerosis (MS) and help improve how health matters are targeted and treated across the entire state.
September 13, 2016 News by Patricia Silva, PhD Gladstone Scientist Wins $5.8M NINDS Award for Work in MS and Neurological Diseases Katerina Akassoglou, PhD, a Gladstone Institutes senior investigator, has been awardedĀ a multiyear, $5.8 millionĀ career grant from the National Institute of Neurological Disorders and Stroke (NINDS) for her work on neurological diseases, including multiple sclerosisĀ (MS). The Gladstone Institutes is a nonprofit community of scientists, affiliated with the…
August 9, 2016 News by Patricia Silva, PhD PCORI Awards $2 Million to Study Treatments for Fatigue in MS Patients The Patient-Centered Outcomes Research Institute (PCORI) recentlyĀ awarded a sum of $5.5 million to two researchers at the University of California, San FranciscoĀ (UCSF). Bardia Nourbakhsh, MD. (Credit: UCSF) Bardia Nourbakhsh, MD, a clinical fellow in Neurology, receivedĀ aĀ $2 million grant to conduct a randomized, double-blind, placebo-controlled clinical trial to…