This new pump could be a major step forward for people with multiple sclerosis who use a pump to deliver baclofen directly into their spinal column. It uses a pressure-driven system rather than a motor-driven one, and involves the use of a handheld device to program on and off flow periods. It also has a battery life of more than 10 years. I wonder how much it will cost and whether insurance providers will cover it.
The U.S. Food and Drug Administration (FDA) has granted approval to Flowonix Medical’s Prometra II Programmable Pump System for use with intrathecal baclofen for the treatment of spasticity across numerous conditions, including multiple sclerosis.
Intrathecal baclofen — sold as Gablofen by Piramal, Lioresal by Saol Therapeutics, and also in generic formulations — is administered via an injection into the spinal canal. It is a skeletal muscle relaxant used to treat spasms, pain, and stiffness. It was designed for individuals who cannot tolerate oral baclofen, or who do not experience relief from tablets.
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Bone Marrow Transplant Can Replace Overactive Immune Cells, Preventing Inflammation in MS, Study Says
I think it’s safe to say that stem cell transplants have proven to be a very effective method for treating some people with MS. But scientists aren’t sure how they work. This research examines the mechanisms involved.
A bone marrow transplant can remove the majority of overactive immune T-cells from the central nervous system (CNS) in patients with active relapsing-remitting multiple sclerosis, allowing the body to replace them with healthy ones, a study has found.
This opens up new treatment avenues to curb immune system impairment and reduce the inflammation associated with the disease.
The study, “Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis,” was published in the journal JCI Insight.
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