biomarker

Blood levels of the nerve damage marker neurofilament light provide a reliable picture of multiple sclerosis activity in both the relapsing-remitting and progressive forms of the disease, a Swedish study reports. The University of Gothenburg researchers also discovered a close link between its levels in blood and spinal fluid. This means the…

The Mayo Clinic has developed a test that allows doctors to distinguish other inflammatory demyelinating diseases from multiple sclerosis in the early stages of a disorder. The test, the first of its kind in the United States, looks for an antibody against a protein known as myelin oligodendrocyte glycoprotein…

Opioid growth factor (OGF) can serve as a new biomarker to determine diagnosis and progression of multiple sclerosis (MS), say researchers at Pennsylvania State University. Their study, “Serum [Met5]-enkephalin levels are reduced in multiple sclerosis and restored by low-dose naltrexone,” appeared in the journal Experimental Biology and…

Scientists have discovered the first blood biomarker for multiple sclerosis (MS) –  a chemical identifier in the blood. The discovery should lead to a simple blood test that makes it quicker and easier to follow the course of MS, a debilitating disease of the central nervous system affecting around 2.3 million people…

In its effort to end progressive multiple sclerosis (MS), the International Progressive MS Alliance (PMSA) has awarded a $6.1 million grant to fund a research project led by Dr. Douglas Arnold with the Montreal Neurological Institute Hospital (MNI) at McGill University. The multiyear grant is one of three…

Researchers from Karolinska Institute, Sweden, reported that the immune-associated protein lipocalin-2 (LCN2) is increased in multiple sclerosis, particularly in patients with progressive MS. The researchers, however, concluded that the factor cannot be used as a biomarker for the disease. The study, “Lipocalin-2 is increased in progressive multiple sclerosis…

A recent study published in the journal PLOS ONE described a new technique with the potential to spot brain changes in multiple sclerosis (MS) before the onset of symptoms. The technique, which measures brain dynamic activity and brain entropy, may lead to the development of diagnostic — and possibly prognostic —…