microglial cells

8 More SPMS Patients Cleared for Foralumab Nasal Spray Treatment

Based on findings from the first two secondary progressive multiple sclerosis (SPMS) patients givenĀ foralumab nasal spray, an experimental therapy, the U.S. Food and Drug Administration (FDA) has approved starting treatment in up to eight other patients under a special access program. Those enrolled in this intermediate-size expanded access…

Foralumab as Nasal Spray Safely, Effectively Treats 1st SPMS Patient

Six months of treatment with foralumab, anĀ experimental nasal spray, safely and effectively improved motor and cognitive function while easing immune activation and inflammatory responses in a person with secondary progressive multiple sclerosisĀ (SPMS), Tiziana Life Sciences, the therapyā€™s developer, announced. The patient ā€” the first with MS to…

MS Progression May Be Tied to Workings of Immune Complement System in Brain Lesions

The complement system, a part of our non-adaptable (innate) immune defenses,Ā is activated in lesions inside the brainā€™s gray matter and may well contribute to the relentless progression of multiple sclerosis (MS), researchers report. The findings offer newĀ insights into mechanisms driving the development of this disease ā€” particularly itsĀ primary progressive forms.

MS Trigger Believed to Lie in Microglial Cells, Scientists Report

Researchers have isolated the particular cell types likelyĀ to initiate common brain disorders and diseases, such as multiple sclerosis (MS) and Alzheimer’s disease, a finding thatĀ may point the way to new and targeted treatments. The brain has a complex cellular architecture characterized by a diverse set of cell types that are…