I’ve been betrayed by my breakfast cereal. Other than eating it, I’m not sure what I did to deserve this. I always liked cereal and thought we had a good relationship. The only disagreement we’ve had was when I tried mixing two high-fiber cereals. The result was a bowl of…
symptoms
Methylphenidate, a stimulant sometimes used to manage fatigue in multiple sclerosis (MS), may also ease oculomotor (eye movement) symptoms and increase how quickly the brain processes visual information, according to a pilot study by Kessler Foundation in New Jersey. “Our findings suggest that methylphenidate could be a beneficial…
A panel of 20 proteins in blood may be used to quantify disease activity, namely relapses and lesions, in people with multiple sclerosis (MS), a new paper proposes. “A multi-protein panel like the one developed in this study has the capability to capture the state of a patient’s MS…
Measures associated with how well individuals can modulate their backward walking speed could be used as a screening tool for mobility and cognition problems in people with multiple sclerosis (MS), according to a study by Michigan researchers. A diminished ability to alter walking speed on demand correlated with worse…
A trip to Taiwan this summer has been years in the making for our family. Our kids have been in Mandarin immersion since preschool, so when their school offered a three-week program for true immersion in Taipei, we jumped at this once-in-a-lifetime opportunity. But dang it is hot and humid…
Dear younger self, As I sit down to write this letter, I can’t help but tear up at the thought of you. First and foremost, you’re an amazing soul, full of life and with a bright future ahead of you. But you’ve just received life-changing news, and it feels…
People with multiple sclerosis (MS) who have cognitive impairment tend to report worse mental and physical quality of life than patients who don’t have cognitive issues, a study reports. Adults with MS who have cognitive problems are also less likely to be employed. The study, “Association…
Note: This column describes the author’s own experiences with high-dose steroids to treat multiple sclerosis (MS). Not everyone will have the same response to treatment. Consult your doctor before starting or stopping a therapy. My first experience treating an MS relapse with intravenous steroids was interesting.
People with multiple sclerosis (MS) have elevated immune responses to more proteins of the Epstein-Barr virus (EBV) than previously thought, according to a new study. EBV-specific immune T-cells isolated from MS patients could also respond to multiple proteins found in the brain, particularly those associated with myelin,…
England’s National Institute for Health and Care Excellence (NICE) has updated its guidance on the use of Mavenclad (cladribine) in people with aggressive relapsing-remitting multiple sclerosis (RRMS) in ways that should help eligible patients be able to access the medication sooner. The new guidelines have less stringent…
A large proportion of people with multiple sclerosis (MS) experience headaches as a result of their condition, and treatment with interferon-based therapies seems to increase the risk of worsening headaches or developing new ones, a study found. In contrast, the CD20 antibody rituximab that’s used off-label in MS…
I have a doctor’s appointment coming up soon. It isn’t with my neurologist or another specialist. It’s a routine visit with my primary care physician and, other than the regular schedule, isn’t really routine at all. There’s a lot more to me than my multiple sclerosis (MS), a fact…
Dormant Epstein-Barr virus (EBV) becomes activated during periods of disease relapse in multiple sclerosis (MS) and triggers inflammatory activity in multiple types of immune cells, a study suggested. Blocking EBV activation can reduce the inflammatory activity of immune cells, supporting the idea that targeting the dormant virus may…
MS Australia released a report highlighting the critical need for faster multiple sclerosis (MS) diagnoses. While diagnostic delays have shortened in recent years, MS patients still wait an average of almost four years from the onset of first symptoms to a formal diagnosis, the organization said in…
I try not to attribute every new symptom I experience to multiple sclerosis (MS). When I was younger, I had an easier time attributing the cause of a new symptom: It was MS or something else. As I age, this differentiation is becoming more difficult. Recently, I experienced new-onset…
As I’ve mentioned in previous columns, I’m now pursuing a doctorate in educational psychology at the University of Texas at Austin. Given that work, 99.9% of my day revolves around typing, despite my multiple sclerosis (MS). My journey as a typist began in high school, when I enrolled…
A higher intake of whole grain food is significantly associated with a lower likelihood of developing pediatric-onset multiple sclerosis (MS), according to a study led by researchers in Canada. Conversely, an overall more pro-inflammatory diet — one containing higher amounts of fats and proteins — was linked to increased…
Scientists in Iran have discovered a new way to convert astrocytes — star-shaped brain cells that support nerve function — into oligodendrocytes, the cells that make and repair myelin in the brain. When the converted cells were transplanted into the brains of mice with myelin damage like that seen in…
There have been so many times I’ve started something but was unable to finish it. There have been so many things I’ve intended to do, but somehow never followed through on them. The gate of my mom’s backyard privacy fence is broken. Half of it is missing. A dear friend…
Certain biomarkers in the cerebrospinal fluid (CSF) — the fluid surrounding the brain and spinal cord — around the time of a multiple sclerosis (MS) diagnosis may help predict the time to reaching certain disability milestones among people with a relapsing-remitting (RRMS) disease course, according to findings from…
An abnormally active metabolism in immune B-cells can trigger the release of pro-inflammatory signaling molecules that drive further inflammation in multiple sclerosis (MS), a study found. Selectively blocking certain metabolic processes with a Bruton’s tyrosine kinase (BTK) inhibitor normalized B-cell metabolism and shifted their signaling to an anti-inflammatory state.
Before multiple sclerosis (MS) took the normal functioning of my limbs, I enjoyed being in the kitchen — not merely to be underfoot or lick spoons and bowls, but to actually cook and bake. I won’t claim to have been a gourmet chef or anything like that, but I…
A small molecule called ESI1 stimulated the repair of the myelin sheath, the fatty coating on nerve fibers that is damaged in multiple sclerosis (MS), a study found. In an MS mouse model, this resulted in improved motor function and nerve cell communication, as well as reduced signs…
Is there something you now have that you once hoped and prayed for? I’ve been struggling with the demands of a new job for the past few weeks. As a virtual dietitian, I heavily rely on computers to meet with clients and do other necessary work. But staring at a…
I feel like I’ve been in this exact place, saying exactly what I’m saying right now. Have I done this in a past life? Did I dream it and am now subconsciously acting it out in reality? Or is my brain performing a fact-check on its memory system and signaling…
A specialized imaging approach was able to detect signs of persistent inflammation in the brains of people with multiple sclerosis (MS) that aren’t readily captured by standard MRI scans. This so-called smoldering inflammation was also observed among those patients taking high-efficacy disease-modifying therapies (DMTs), where a higher degree…
For people who develop multiple sclerosis (MS), the disease can exact a toll on their ability to work and on how much they earn in the private sector, according to a study by researchers in France, who said policies need to be enacted to replace lost income. “The effects…
Even as a small child, I enjoyed watching nature shows. They didn’t come on television often, but when they did, I absorbed every word. At school, I might not have been able to recite the Pythagorean theorem, but I could say with confidence that butterflies taste with their feet. That…
Fully 70% of patients with nonactive secondary progressive multiple sclerosis (SPMS) who received foralumab nasal spray in an expanded access program (EAP) experienced a lessening in fatigue levels after six months of treatment. That’s according to early findings from the EAP — a program that enables patients with serious…
Researchers have identified a distinct profile of self-reactive antibodies that appear in the blood years before the first clinical signs of multiple sclerosis (MS), which they believe could be used to help diagnose the neurodegenerative disease. The antibodies were found in about 10% of people who developed MS and…