Gilenya Outperforms Avonex in Lessening Brain Lesion Activity, Atrophy in Children with MS, Trial Shows
Oral treatment with Gilenya (fingolimod) is more effective than Avonex (interferon beta-1a) for controlling brain…
Articles by Ana Pena PhD
Canadian Study Reports Fewer MS-related Hospital Admissions as Patients Age and Among Women
Older age, a greater number of health conditions, and prior hospital admissions are associated with more hospitalizations due to all…
#ACTRIMS2020 – CNM-Au8 a Potential ‘Breakthrough’ in MS Therapy, Clene CMO Says
An investigational therapy that uses nanocrystals of gold to help the brain repair itself represents a breakthrough in the…
Blood NfL Potential Marker of MS Therapies’ Effectiveness, Study Suggests
Starting treatment with a disease-modifying therapy (DMT) reduces blood levels of neurofilament light chain (NfL) — a potential biomarker of…
#ACTRIMS2020 – What We Now Know About Diet and MS
What science has told us about how diet might influence a person’s risk of multiple sclerosis and a patient’s…
#ACTRIMS2020 – 3 Ways to Treat MS by Altering Gut Microbiome Under Study
Modulating the bacteria that reside in the gut by treating multiple sclerosis (MS) patients with probiotics, fecal transplants, or gut-related…
#ACTRIMS2020 – IL-13 May Be ‘Attractive’ Target for Easing Inflammation in MS
A signaling molecule of the immune system called interleukin 13 (IL-13) may modulate the function of key immune cells involved…
#ACTRIMS2020 – Ozanimod May Ease Inflammation While Retaining Some Immune Defenses
Ozanimod — an investigational oral therapy up for approval to treat relapsing multiple sclerosis (MS) — lowers…
#ACTRIMS2020 – CorTechs Says AI Models May Improve Early MS Diagnosis
CorTechs Labs presented new data indicating that machine learning models based on magnetic resonance imaging (MRI)…
#ACTRIMS2020 – Ofatumumab Self-injection Pen Equivalent to Prefilled Syringe, APLIOS Trial Shows
Using a patient-friendly autoinjector pen to take monthly doses of ofatumumab — an investigational B-cell therapy…
#ACTRIMS2020 – Protein May Drive Process Causing T-cells to Attack Myelin
A protein called dedicator of cytokinesis 8 (DOCK8) is key for the development and expansion of self-reactive immune T-cells that…
#ACTRIMS2020 – Vitamin D at High Dose Can Worsen MS, Early Study Says
High-dose vitamin D supplements appear to aggravate inflammation and myelin loss in the brain and spinal cord,…
#ACTRIMS2020 – Early Trial Data Support CNM-Au8 Improving Vision, Physical Abilities
Clene Nanomedicine shared early results of the VISIONARY-MS trial, suggesting that CNM-Au8 — an…
#ACTRIMS2020 – Remyelination in Adult Animal Brains Possible via Cell Transplant, Study Says
Transplanting human glial progenitor cells (GPCs) — brain cells able to generate myelin-producing cells — effectively led to remyelination in…
#ACTRIMS2020 – Pregnancies and Menopause Affect Age of Progressive MS Onset
Women with multiple sclerosis (MS) who have never given birth and those who began menopause prematurely tend to develop…
How Astrocytes Promote Inflammation in Patients’ Brain Detailed in Early Study
Using brain tissue from people with multiple sclerosis (MS) and mouse models of MS, scientists identified a key pathway…
Ocrevus Use Rises Among New Starters with RRMS, Loses Ground to Other Therapies in PPMS
First-line use of Genentech‘s Ocrevus (ocrelizumab) for patients with multiple sclerosis (MS) has remained stable through 2019…
Gold Nanocrystals in Phase 2 Testing Show ‘Robust’ Remyelination Potential in Animal Models
Clene Nanomedicine‘s remyelination therapy candidate, CNM-Au8, showed a “robust” ability to stimulate the production of new myelin…
Mavenclad May Be Added to RRMS Treatments on Quebec’s Public Health Plan
Immune cells have an inflammation ‘switch’ that involves the NLRP3 inflammasome pathway, and…
FDA OKs Device to Monitor Blink Reflex, Potential Way of Detecting MS Early
EyeStat, a portable device to measure blink reflex, has been cleared for use by the U.S. Food and…
New Research Shows How Nerve Impulses Travel, May Offer Insights to Effects of MS Demyelination
Nerve impulses travel in a “dual cable” with myelin, playing additional roles to what was previously thought, new research…
Gene Therapy Recovers Vision in Mice Models of MS, Uncovers How Neuron Connections Are Destroyed
Early research in animal models and human samples reveals how loss of communication between nerve cells contributes to the…
Being Bilingual May Help to Delay Cognitive Decline in MS, Study Suggests
An ability to speak more than one language may help to protect people with multiple sclerosis (MS) against the…
Magenta Therapeutics to Advance Safer Immune Reset Therapy for MS Stem Cell Transplant in 2020
Magenta Therapeutics will continue to advance its investigational conditioning therapy CD45-ADC for patients with autoimmune diseases undergoing stem cell…
Top 10 Multiple Sclerosis Stories of 2019
Throughout 2019, Multiple Sclerosis News Today brought you daily coverage of the latest scientific findings, treatment developments, and clinical trials related…
Future MS Trials Should Focus on Patient Experience, Providing Long-term Data, Working Group Says
Trials testing new immunotherapies for multiple sclerosis (MS) should focus more on patients’ experiences and on symptoms relevant…
Treatment Begins in Part 2 of Trial of Software App Addressing Depression in MS, Pear Says
Pear Therapeutics announced that a first patient is being treated in Part 2 of its feasibility trial of Pear-006,…
Astrocytes in Brain Seen as Possible Trigger of Progressive MS via Processes of Metabolism
Processes related to metabolism in brain cells known as astrocytes may be at…
microRNA Found in Gut Microbiome May Unlock Future Therapeutic Approach for MS
A small RNA molecule found in high levels in the gut of people with multiple sclerosis (MS) could…
MS Risk Linked to Herpes Virus 6A and Not More Common 6B, Study Suggests
Human herpesvirus 6A (HHV-6A), but not a widespread variant of the virus called HHV-6B, could be one of the…