Cyxone Launches Phase 1 Trial Assessing T20K for MS
Cyxone launched the first-in-human Phase 1 clinical trial assessing the effects of T20K, its new therapeutic candidate for the…
Articles by Joana Carvalho, PhD
Immune System Activation Induced by Filgrastim Likely Beneficial for Patients with Tysabri-associated PML, Study Says
Immune system activation induced by filgrastim may be beneficial for patients with progressive multifocal leukoencephalopathy associated with the…
Neurological Disease’s Progression Slows with Lowering of Iron Load in Brain, Study Finds
Deferiprone, a compound that lowers iron levels in the bloodstream by binding to iron molecules, can slow progression of…
New AI Method Detects Brain Changes in Response to Treatment in RRMS Patients
A new artificial intelligence (AI)-based model is better than conventional methods for detecting brain changes in response to treatment with…
FDA and EMA to Review Ozanimod as Possible Oral Therapy for Relapsing MS
The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) both agreed to review for…
Mavenclad May Surpass Gilenya as DMT of Choice for Treatment of MS in Canada
Mavenclad (cladribine) may surpass Gilenya (fingolimod) in the category of oral disease-modifying therapy (DMT) of choice for the…
EMD Serono and ‘MS Inside Out’ Campaign Join Global Effort to Make MS More ‘Visible’
EMD Serono is supporting World MS Day, an initiative created by the Multiple Sclerosis International Federation…
MS International Federation Urges Participation in Visibility Campaign on World MS Day
The Multiple Sclerosis International Federation (MSIF) is encouraging family members, caregivers, and patients affected by multiple sclerosis (MS)…
IPMSSG Issues Guidelines on Participation of MS Youngsters in Clinical Trials
The International Pediatric Multiple Sclerosis Study Group (IPMSSG) has updated its guidelines regarding the participation of children and adolescents…
Reactivation of Ancient Viruses May Be Involved in MS Inflammatory Response, Study Says
Reactivation of ancient viruses incorporated into the human genome in the course of evolution may be involved in the acute…
Simvastatin, Common Statin, Treats SPMS in Ways Distinct from Cholesterol, Study Suggests
Simvastatin, a widely prescribed statin that works to lower cholesterol levels, may slow brain atrophy and disease progression in…
Lyfebulb and Celgene Announce 2019 Innovation Challenge Finalists
Lyfebulb and Celgene have announced the 10 finalists who will compete for a $25,000 grant to support…
Ocrevus Approved in UK as First NHS Treatment for PPMS
After first rejecting it due to cost-effectiveness concerns, the National Institute for Health and Care Excellence (NICE) has now…
#AANAM — Adamas Provides Update on Phase 3 INROADS Trial Testing ADS-5102 for MS
Adamas Pharmaceuticals announced the study design and baseline characteristics of patients enrolling in the company’s ongoing Phase 3…
Women with MS Have Higher Prevalence of Sexual Dysfunction, Study Reveals
Women with multiple sclerosis (MS) are more likely to experience sexual dysfunction and sexual distress than those without the…
MS Trust Promotes Multiple Initiatives in UK to Encourage Exercise
The Multiple Sclerosis (MS) Trust, a charity organization that provides support to MS patients in the United Kingdom, is…
14 Notable Pilot Projects Among Research Efforts Funded by National MS Society
The National Multiple Sclerosis Society has recently awarded $24.4 million in grants to support 64 research projects on…
EMA Reviewing Safety Data for Lemtrada After Reports of Serious Treatment Side Effects
The European Medicines Agency (EMA) is reviewing safety data for Sanofi Genzyme‘s Lemtrada (alemtuzumab) following new reports of serious…
National MS Society Grants $24.4M to Fund 64 MS Research Projects
The National Multiple Sclerosis Society has granted $24.4 million to fund 64 multiple sclerosis (MS) research projects and training…
NeurologyLive Launches Series of Educational Videos About MS
NeurologyLive has launched a series of educational videos intended to provide an overview of the diagnositic methods and…
FDA Approves EMD Serono’s Mavenclad as Treatment for RRMS and Active SPMS
The U.S. Food and Drug Administration (FDA) has approved Mavenclad (cladribine) tablets for the treatment of adults with…
T20K in Good Position to Become Preventive MS Treatment, Cyxone Says
T20K, Cyxone‘s lead compound for treating multiple sclerosis (MS), seems able to prevent or slow disease progression, according…
Low Socioeconomic, Education Levels Linked to Higher Disability and Disease Progression in MS, Study Says
Low income and education levels are linked to a higher risk of physical disability and disease progression in patients with…
In Creating ‘Immune Cell Atlas of Brain,’ Scientists Find Microglia Highly Complex in Behavior and Role
In mapping the immune system of the brain in mice and humans, scientists in Germany found that microglia — a type…
Mindfulness Protects Against Depression, Anxiety, Fatigue, and Sleep Issues in MS Patients, Study Finds
Mindfulness protects against depression, anxiety, fatigue, and sleep problems in patients with multiple sclerosis (MS), improving their…
Each Major Risk Factor (Like Genes, Smoking and Obesity) Can Affect Disease Course, Study Finds
Risk factors often associated with multiple sclerosis (MS), such as genetic background, obesity and smoking, contribute independently to the…
Phase 3 Trial of MD1003 in Treating Progressive MS Fully Enrolled, MedDay Announces
A Phase 3 clinical trial intending to confirm the potential of MD1003, a high-dose biotin, in treating progressive multiple sclerosis (MS)…
PRIMERS Framework Aims to Better Understand How Exercise Helps Movement and Cognition in MS Patients
A new conceptual framework, called PRIMERS, has been proposed as a way of better understanding how physical exercise works to improve…
Pregnancy Rates Rise Among Women with MS Over Past Decade in US, Study Shows
In recent years, pregnancy rates have increased among women with multiple sclerosis (MS) in the United States, according to…
Exercise Fights Fatigue and Depression in MS Patients, Study Reveals
Physical exercise fights fatigue and depression in patients with multiple sclerosis (MS), a new study reveals. Remarkably,…