Author Archives: Joana Carvalho

Cyxone Launches Phase 1 Trial Assessing T20K for MS

Cyxone launched the first-in-human Phase 1 clinical trial assessing the effects of T20K, its new therapeutic candidate for the treatment of multiple sclerosis (MS), in healthy volunteers. The announcement came after the company received approval from the Dutch Ethics Committee and Central Commission on Research Involving Human…

Immune System Activation Induced by Filgrastim Likely Beneficial for Patients with Tysabri-associated PML, Study Says

Immune system activation induced by filgrastim may be beneficial for patients with progressive multifocal leukoencephalopathy associated with the use of Tysabri (natalizumab), without worsening multiple sclerosis (MS) progression, a study says. The study with that finding, “Treatment of natalizumab‐associated PML with filgrastim,” was published in…

Ocrevus Approved in UK as First NHS Treatment for PPMS

After first rejecting it due to cost-effectiveness concerns, the National Institute for Health and Care Excellence (NICE) has now approved the use of Ocrevus (ocrelizumab) for people in the U.K. with early, inflammatory primary progressive multiple sclerosis (PPMS). This means that PPMS patients living in the…

MS Trust Promotes Multiple Initiatives in UK to Encourage Exercise

The Multiple Sclerosis Trust, a charity organization that provides support to MS patients in the United Kingdom, is urging them to remain active and find ways to introduce physical activity into their daily routine, as part of its "Move it for MS" campaign. The organization's appeal about the benefits of exercise for MS patients is particularly focused during MS Awareness Week (April 22-28). In the past, exercise was regarded as something that should be avoided by people with MS. This was due to the belief that any tiring activity might raise the body's normal temperature and possibly worsen patients' fatigue and other MS symptoms. Research has proven that is not the case. In fact, several studies have shown that moderate, regular physical activity may help people with MS manage their symptoms and improve their overall quality of life. Throughout this week, MS Trust is planning a series of initiatives to encourage MS patients to be creative and seek ways to remain physically active. These include sharing testimonials of patients who felt exercise has improved their physical and mental well-being, as well as launching a series of Pilates-style exercise-friendly videos, developed in collaboration with a neuro-physiotherapist, that people with MS can watch and practice at home. "Exercise has made me much more confident because I am so much stronger now. I used to not want to go out on my own, but now I have no fear," Lee Gibbs, one of the supporters of MS Trust, said about the organization's campaign. At the organization's Facebook page, workouts and dance classes also will be available. MS Trust also is promoting another initiative that will take place throughout May called "Miles for MS." That initiative allows each participant to set his own goals, whether it may be to run 100 miles or cycle 20 miles (divided into smaller sessions), to complete during the month of May. People who decide to register and participate in the initiative will receive an exclusive MS Trust T-shirt, and a personalized online fundraising website where they will be able to track their progress, raise funds to support people living with MS, and obtain a certificate. Participants who succeed raising more than £125 (about $162) also will receive a special "Miles for MS" medal. For more information about "Miles for MS" initiative visit this link.

NeurologyLive Launches Series of Educational Videos About MS

NeurologyLive has launched a series of educational videos intended to provide an overview of the diagnositic methods and treatment options available to multiple sclerosis (MS) patients. The video series, “Advances in the Diagnosis and Management of Multiple Sclerosis,” also will include future perspectives on upcoming MS therapies,…

Phase 3 Trial of MD1003 in Treating Progressive MS Fully Enrolled, MedDay Announces

A Phase 3 clinical trial intending to confirm the potential of MD1003, a high-dose biotin, in treating progressive multiple sclerosis (MS) patients is completely enrolled, MedDay Pharmaceuticals, the investigational therapy’s developer, announced. The randomized, double-blind, and placebo-controlled study (NCT02936037), called SPI2, follows the previous Phase 3 trial (NCT02220933),…

Exercise Fights Fatigue and Depression in MS Patients, Study Reveals

Physical exercise fights fatigue and depression in patients with multiple sclerosis (MS), a new study reveals. Remarkably, these positive outcomes in psychological health can be achieved without significant alterations in the patient’s body weight or body mass index (BMI), further supporting the idea that exercise could be…

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