MS progression

Most disability worsening on Ocrevus not tied to relapses: Study

Among multiple sclerosis (MS) patients treated with Ocrevus (ocrelizumab), most of the disability worsening they experience is not associated with any relapse activity, according to an analysis of real-world data. “We present real-world data from our multiple sclerosis center underlining that in a typical population of relapsing MS…

Greater MS disability reported in patients with COVID-19 infection

Infection with the virus that causes COVID-19 significantly accelerates neurological disability in people with multiple sclerosis (MS), at least in the first months after infection, a study from Belgium reported. A more severe case of COVID-19, one requiring hospitalization, also significantly associated with a faster worsening of MS…

Progression Without Relapse Also Common in RRMS, Patients Say

Nearly two-thirds of people with relapsing-remitting multiple sclerosis (RRMS) report disease progression independent of relapses, according to a survey involving more than 4,500 multiple sclerosis (MS) patients in Germany. This finding supports evidence pointing to progression independent of relapse activity (PIRA) as an underestimated contributing factor in RRMS.

Thanks to MS Progression, My Weight Became a Problem

My weight went off the scale when my multiple sclerosis (MS) meant that I could no longer safely get on the scale. This was probably about four years ago. In them there halcyon days (for me, anyway), I still shared our second-floor bedroom (first-floor, for those of us here…

Review Gives ‘Cautious Support’ to Childhood Trauma as MS Risk Factor

Most available studies suggest a connection between childhood trauma and multiple sclerosis (MS), from earlier symptom onset to potentially poorer outcomes, but more research is needed to understand this association, a review paper highlights. While several high-quality studies have been published, the scientists noted “considerable heterogeneity [variability] in methodology, including inconsistencies…

Imaging of Retina Can Help in Monitoring Nerve Cell Damage in MS

An imaging technique called optical coherence tomography (OCT) could be useful for monitoring nervous system damage in people with multiple sclerosis (MS), especially early on in the disease, a study in patients reports. The study, “Optical coherence tomography in multiple sclerosis: A 3-year prospective multicenter study,”…

#ACTRIMS2021 – Benign Versus Aggressive MS – the Hunt for Clues

Editor’s note: The Multiple Sclerosis News Today news team is providing in-depth and unparalleled coverage of the virtual ACTRIMS Forum 2021, Feb. 25–27. Go here to see the latest stories from the conference. While researchers make progress in pinpointing markers of disease progression in multiple sclerosis (MS), identifying those that signal…

Need to Know: What Does MS Progression Mean?

Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum post “Number, Location, Size of Lesions on MRI Can Predict Progression to MS,”…

Thankful Awakening: Accepting Change with SPMS

My happiness quotient correlates with my ability to give. I find tremendous satisfaction in doing this. This is one reason that I cherish Thanksgiving. I derive immense pleasure in creating this symbolic meal for those I love. For a subpar cook, I knock the socks off the classic Thanksgiving…

How Diet Helped Creator of Wahls Protocol in Personal MS Journey: A Nutritionist’s View

In my recent conversation with Terry Wahls, MD, creator of the Wahls diet for multiple sclerosis (MS), she said something that resonated with me: “You can’t change your genes, but you can change your gene’s expression.” How true this statement is. However, it was only a few short years ago that Dr. Wahls’ diet protocol, and “food as medicine” philosophy was being met with strong criticism from the medical community. Nowadays, the modified paleolithic diet and lifestyle program she facilitates at the Wahls Institute in Iowa is being touted as the work of a visionary.

Vitamin D May Help Lessen MS Symptoms, Some Studies Suggest

To grasp the connection between vitamin D and multiple sclerosis (MS), it is first important to understand this vitamin’s power. It is one of the “superhero” vitamins needed to help keep our bodies functioning properly. According to the Cleveland Clinic, vitamin D is essential for us to absorb the…

PPMS Suddenly and Spontaneously Surges My Symptoms

When I was diagnosed in 2010 with primary progressive multiple sclerosis (PPMS), I didn’t know what to expect. It quickly became apparent that my doctors didn’t know, either. I’m sure they could have given me some scenarios of what my future might be…