August 24, 2023 News by Marisa Wexler, MS Aubagio reduces MS risk in people with disease-like signs: Phase 3 trial Aubagio (teriflunomide) can significantly reduce the risk of developing multiple sclerosis (MS) among adults with signs of MS-like brain damage who don’t yet have any disease symptoms, according to findings from a clinical trial. The results were presented earlier this year at the American Academy of Neurology…
November 1, 2022 News by Marta Figueiredo, PhD #ECTRIMS2022 ā Tecfidera Lowers Risk of 1st Symptoms in RIS in Trial Treatment with Tecfidera (dimethyl fumarate) significantly reduces the risk of experiencing the first multiple sclerosis (MS) symptoms in adults with radiologically isolated syndrome (RIS), according to data from a Phase 4 clinical trial. RIS is a condition in which patients have MS-like lesions on MRI scans, but…
February 25, 2022 News by Marisa Wexler, MS #ACTRIMS2022 ā Paramagnetic Rim Lesions ‘Highly Specific’ Markers of MS Paramagnetic rim lesions, a specific form of inflammatory damage to the brain, are rarely found in people with disorders other than multiple sclerosis (MS), according to a study in adults with suspected MS. Its findings suggest that looking at PRLs could be useful for diagnosing the disease. Brain Renner,…
February 4, 2022 News by Margarida Maia, PhD Researcher Will Use Award to Find Biomarkers of RIS in Children This yearās Harry Weaver Neuroscience Scholar Award, funded by the National Multiple Sclerosis (MS) Society, has gone to a Yale University researcher who is searching for biomarkers of radiologically isolated syndrome (RIS) in children. RIS occurs when imaging findings on MRI scans are similar to those seen in people…
December 10, 2021 News by Marisa Wexler, MS National MS Society Funds 13 New Research Projects The National MS Society has announced it is funding 13 new research projects that seek to better understand the risk factors involved in multiple sclerosis (MS) development and progression. The funding ā nearly $7 million in total ā also will go to “rescue” 22 MS-related research projects that…
November 8, 2021 News by Marisa Wexler, MS Younger Age, Certain Lesions Linked to Higher MS Risk for RIS Patients Among people with nervous system damage indicative of multiple sclerosis (MS), but who don’t yet have the disease ā a condition known as radiologically isolated syndrome or RIS ā the risk of progressing to full-fledged MS is higher for those who are younger, have spinal cord lesions, and have…
May 7, 2021 News by Vanda Pinto, PhD Phase 4 Trial Will Test if Ocrevus Can Prevent MS Onset in RIS Patients Yale University is launching CELLO, a multicenter study to investigate the efficacy of Ocrevus (ocrelizumab) in treating people with lesions suggestive ofĀ multiple sclerosis (MS), a condition known as radiologically isolated syndrome. The Phase 4 study (NCT04877457) aims to evaluate whether short-term treatment with Ocrevus can…
July 20, 2020 Columns by Ed Tobias MS News That Caught My Eye Last Week: COVID-19 Website, Testing MS Progression, RIS, Alternative Treatments MSAA Opens āCOVID-19 and MS Pathfinderā Online Informative Platform Information about MS and COVID-19 is dynamic and regularly changing. This has been particularly true about how to handle disease-modifying therapies (DMTs). The website mentioned in this story tries to keep up with these changes while covering multiple subjects ranging…
July 14, 2020 News by Marisa Wexler, MS Most RIS Patients Likely to Progress to MS Within 10 Years, Study Says More than half of people with brain imaging changes akin to multiple sclerosis (MS) go on to develop the disease within 10 years, a global study of those with radiologically isolated syndrome reported. Progression to MS appears to be more likely in those who are younger, have spinal…
March 4, 2019 News by Jonathan Grinstein #ACTRIMS2019 – Two MRI Biomarkers Can Potentially Distinguish RIS from Other Disorders Two new magnetic resonance imaging (MRI) biomarkers ā called central vein sign and paramagnetic rim sign ā could be useful for differentiating true radiologically isolated syndrome (RIS) patients from those with mimicking features, new research shows. The findings were presented at theĀ Americas Committee for Treatment and Research in Multiple…
October 26, 2017 News by Patricia Silva, PhD #MSParis2017 – Researchers Disagree on Feasibility of Using Disease-modifying Therapies in RIS Patients Radiologically isolated syndrome (RIS) is a rare and relatively recent condition in which people have multiple sclerosis (MS)-like brain and spinal cord lesions without showing disease activity. But since the establishment of the RIS diagnosis, researchers have not reached an agreement on whether these patients should receive MS disease-modifying therapies.
October 13, 2017 News by Patricia Silva, PhD MRI Scans Could Identify Children at High Risk for MS, Yale Study Finds Magnetic resonance imaging (MRI) brain scans of children could reveal changes associated with multiple sclerosis (MS) before any symptoms are developed, according to a study byĀ scientists at Yale University School of Medicine. The findingsĀ suggest that brain and spinal cord scans can identify children at high risk for developing MS.