Two specific bacteria present together in the gut led to more immune attacks on myelin and harsher symptoms in a mouse model of multiple sclerosis (MS). These findings add to existing evidence supporting the link between gut microbiota and MS, and highlight the need to consider potential combined effects of these…
Diet and nutrition
The number of new cases of multiple sclerosis (MS) possibly due to obesity in childhood and adolescence could rise by 14% in the U.S. over the next 15 years, and by 10% in the U.K., a study reported. While the worldwide risk of MS linked to obesity in early life…
Your alarm sounds at 7 a.m. You grunt, smash the snooze button, and turn over. Ten minutes later, your alarm sounds again. You smash snooze. And repeat another five times. Eventually, you reach for your phone with a…
Therapeutics Solutions International has announced filing a new patent covering the memory protective effects of its natural nutritional supplement QuadraMune, as seen in an animal model of memory loss caused by inflammation. QuadraMune is a nutritional supplement, available in capsule form, made of four ingredients with known anti-inflammatory, neuroprotective, and…
Drinking coffee each day appears to help people with multiple sclerosis (MS) and milder disability and fatigue, with this patient group reporting in a questionnaire that caffeine allowed them to better concentrate on tasks and broaden their attention spans, a study reports. Its researchers suggest that “for selected patients” regular coffee…
A “prudent” diet rich in fresh fruit, non-fried fish, whole grains, vegetables, and nuts may lower the likelihood of a relapse in people with a first demyelinating event, a major risk factor for multiple sclerosis (MS), a study in Australia suggests. While the researchers did not find a strong link…
Multiple sclerosis (MS) patients who are obese experience faster degeneration in optic nerve tissue than do those of normal weight, an observational study found. Since optic nerve degeneration correlates with greater nerve loss in the brain, measuring changes in this tissue may be a feasible way to determine…
Tweaking the protective properties of the gut mucus, a layer lining the inside of the gut, to boost the proliferation of good bacteria potentially could halt the development of neurological disorders, like multiple sclerosis (MS), according to a review of more than 100 studies. The review, “…
Multiple sclerosis (MS) patients who are obese experience a faster degeneration in their optic nerve tissue than those of normal weight, a study found. Since optic neuropathy correlates with greater nerve cell loss in the brain, tracking changes to the retina may be a feasible way to determine…
Ursolic acid, a compound found in some herbs and in the peels of certain fruits, promoted nerve cell repair and restored the myelin sheath covering and protecting nerve endings in a mouse model of multiple sclerosis (MS), a study reported. Due to its strong anti-inflammatory and immunomodulatory…
Altering Gut Microbiota May Be Beneficial Prior to MS Onset, But Not After, Mouse Study Indicates
Changing the gut’s microbial community (microbiota) with antibiotics prevented the development of multiple sclerosis (MS), but not its progression after the disease was established, data from a mouse model of the disease show. These findings support evidence that microbiota manipulations affect inflammatory immune responses involved in MS development, but…
Regular Exercise ‘Strongly Recommended’ to Ease Fatigue in MS This may seem like a no-brainer. But once upon a time, neurologists told people with MS to avoid exercise. They told us it would overheat us or make us tired. Over the past few years, this advice has flipped 180…
A study from Spain found the diet of multiple sclerosis (MS) patients to contain more fat and protein, and fewer carbohydrates, than recommended, which was linked to abdominal weight gain and higher levels of inflammation. As “an excessive intake of lipids” is known to be “related to oxidative stress…
Continuous production of fatty molecules (lipids) is crucial to the maintenance of the myelin sheath that wraps nerve fibers to protect them, ensuring the transmission of electrical impulses between nerve cells, a study reported. These findings may have strong implications for treating disorders caused by myelin loss, including…
A short-chain fatty acid produced by gut bacteria helps to counteract inflammatory responses in multiple sclerosis (MS) by promoting greater numbers of regulatory immune cells, a study reports. But the bacterial composition of the gut (its microbiome) of MS patients is deficient in bacteria that produce this acid —…
MS News that Caught My Eye Last Week: Coronavirus FAQs, Diet, Ozanimod Study, High-dose Vitamin D
FAQs About Coronavirus and MS As the coronavirus that causes the COVID-19 disease spreads around the world, people with multiple sclerosis are asking questions specifically related to our illness and our medications. These FAQs answer many of those questions. The recent outbreak of a novel…
What science has told us about how diet might influence a person’s risk of multiple sclerosis and a patient’s disease course was the topic of discussion at a recent MS conference. Ellen Mowry, MD, a researcher and professor of neurology at John Hopkins, also reviewed some of the dietary…
Modulating the bacteria that reside in the gut by treating multiple sclerosis (MS) patients with probiotics, fecal transplants, or gut-related microRNAs may help to ease inflammation and disease severity, researchers with Brigham and Women’s Hospital suggest. Howard Weiner, MD, a group leader at the hospital, presented his team’s findings on…
Placing a feeding tube before age 50 in multiple sclerosis (MS) patients with dysphagia, or difficulties swallowing, may extent their life by more than two years, a study suggests. These findings may help doctors and patients with decisions about feeding tube use, but more work is needed to better understand…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by “Newly Diagnosed MS Patients Show Changes in Gut Microbiome, Study Says,” from Dec. 3, 2019.
Changing a person’s diet to reduce the amount of methionine (amino acid found in food) could delay the development and progression of inflammatory and autoimmune disorders, including multiple sclerosis (MS). That finding was described in the study “…
Here’s My ‘Veganuary’ Report
I’m well aware that new converts can be bores. I started an increasingly trendy vegan lifestyle back in December. It’s only been two months, but it seems like a year! That’s because I love meat, fish, cheese, and eggs. Especially eggs. Yes, veganism is better for the planet, your…
Only 347 shopping days to go! So don’t dismiss this as a column about last Christmas (though that’s what it is!) but as possibly the first on the planet about the next one. Luckily, I quite like nut roast. But it is very much “quite” like. I don’t like it…
Weight Loss Diets Rare Among Obese MS Patients Despite Link to Disease Progression, Study Suggests
Despite the fact that being obese or overweight may worsen multiple sclerosis (MS) prognosis, people with the neurodegenerative disease are not more likely to adopt weight loss diets, a small study suggests. The study, “Obesity, dieting, and multiple sclerosis,” was published in the journal Multiple Sclerosis and Related…
Probiotics show potential to prevent and delay the development of multiple sclerosis (MS) by changing immune and inflammatory responses, according to a review study. Data further support the link between the gut’s microbial community (microbiota) and the central nervous system (brain and spinal cord), and neurodegenerative diseases. However, large-scale clinical…
With “The Terminator” involved, it’s fair enough that this tale starts out as a father-son thing. My son, Jack, kept needling me to watch a film on Netflix U.K. called “The Game Changers.” My wife had also watched it and heavily backed the suggestion. Both had a knowing gleam…
Multiple sclerosis (MS) is a neurodegenerative disorder in which the immune system mistakenly attacks the protein coating that protects nerve fibers from damage. It is unknown what triggers the immune system’s attack, but many MS treatments are targeted at reducing inflammation to curb the activity of the immune system.
Depleting microbes in the gut of mice led to an altered fear response, changes in gene expression in brain immune cells and changes in brain chemistry — returning to a more normal state after their gut microbes were restored, but only if done early in life, a study…
Many treatments for multiple sclerosis (MS) are targeted at reducing inflammation, thereby slowing progression of the autoimmune disease. An anti-inflammatory diet also may slow disease progression, as well as enhance the positive effects of anti-inflammatory medications. In MS, the immune system mistakenly attacks the protein coat that surrounds nerve…
The National Multiple Sclerosis Society (NMSS) awarded $14.6 million in grants supporting 43 new and multiyear research projects into multiple sclerosis (MS), part of a projected $36 million investment in disease research for 2019, the society announced on its website. Funded projects include research into new ways of halting progressive MS, the…