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Multiple Sclerosis Treatments Benefit From Discovery of New Inflammatory Molecule

A newly discovered molecule could play a pivotal role in inflammatory diseases, including multiple sclerosis, according to researchers at Trinity College Dublin and the University of Queensland Australia. The study was published in the journal Nature Medicine, and describes a molecule known as MCC950 that can suppress the ‘NLRP3 inflammasome’,…

A Step Toward Multiple Sclerosis Treatment? Phase 2 ANTI-LINGO-1 Results Announced

Biogen Idec, a Cambridge Massachusetts Biotechnology company, has released results from its Phase 2 acute optic neuritis (AON) RENEW trial. The trial tested anti-LINGO-1, a medication that restores myelin — a fatty substance that facilitates nerve cell impulses by wrapping around them and providing insulation. The trial results indicate that anti-LINGO-1…

Multiple Sclerosis Risk Does not Increase with HPV Vaccine According to Study

Human papillomavirus (HPV) vaccination can help protect against several health problems, including cervical cancers in women. Some reports have raised concerns however, that the vaccine might actually increase the risk of developing multiple sclerosis. A study entitled “Quadrivalent HPV Vaccination and Risk of Multiple Sclerosis and Other…

Long-Term Multiple Sclerosis Progress Can Be Better Determined Using NEDA Standard

A study published on December 22 in JAMA Neurology emphasizes that a standard measurement used to gauge multiple sclerosis (MS) symptoms, known as “no-evidence-of-disease-activity” (NEDA) is important for determining how the disease will progress long-term. MS is the most common degenerative neurological condition that affects young adults worldwide.

Can Tryptophan Help Improve Memory in Multiple Sclerosis Patients?

Have you ever eaten a turkey dinner and afterwards someone says that the feeling of drowsiness is caused by the tryptophan in the meat? According to Texas A&M University Professor Dr. Nicolaas Deutz, “This story about tryptophan in turkey is just kind of a running joke, it has nothing…

Unraveling Myelin’s Mystery With Neutron Diffraction

Researchers have uncovered new information about myelin, a fatty substance that wraps around the axons of brain cells (neurons) allowing them to transmit information quickly from one cell to another. De-myelinating diseases in which the insulating wrap is damaged include multiple sclerosis, in which unpredictable loss of myelin causes…

Failure of Brain Development in Early MS Suggests Need for Neuroprotection

Researchers from Canada and the U.S. have found that brains of young people with multiple sclerosis fail to develop fully. The article appeared November 5, 2014 in the journal Neurology entitled, “Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth.” Multiple sclerosis is caused…

Scientists Block Multiple Sclerosis in Mice Using Estrogen-Like Drug

A team of researchers at the University of California, Riverside, along with other collaborators, have identified a drug associated with estrogen, indazole chloride (Ind-Cl), that blocks the effects of multiple sclerosis (MS). The findings were reported December 1st in the Proceedings of the National Academy of Sciences. MS…

Newly Identified Immune Cell Sheds Light on Multiple Sclerosis Cause

Researchers from the National University of Singapore have found a new type of immune cell that could aid in the development of treatments for multiple sclerosis (MS). The study was published on November 21 in the journal Cell Research entitled, “STAT5 programs a distinct subset of GM-CSF-producing T helper…

Oceans of Hope Yacht For MS Awareness Anchored In Boston

The Oceans of Hope yacht, part of the Sailing Sclerosis Foundation project, has recently arrived in Boston after its transoceanic trip from Lisbon, the first by a crew of people with multiple sclerosis, announced the foundation through its webpage. The yacht, which started its sailing journey in…

Researchers Find MS Drug Fingolimod Decreases Gd-enhancing Lesions

Fingolimod is a disease modifying therapy (DMT) used to treat relapsing remitting multiple sclerosis (RRMS) patients as well as patients who continue to present with relapses despite treatment with beta interferon drugs, and is the first oral medication to be approved by the U.S. Food and Drug…

New Relapsing-Remitting Multiple Sclerosis Drug Approved By FDA

Biogen Idec, a biotechnology company focused on developing innovative therapies for the treatment of neurodegenerative diseases, hematologic conditions and autoimmune disorders, has announced that the U.S. Food and Drug Administration (FDA) has approved PLEGRIDYTM (peginterferon beta-1a), a new treatment for people with relapsing forms of multiple sclerosis…

HIV Infection May Suppress Development of MS, According To Study

According to a study published in the Journal of Neurology Neurosurgery & Psychiatry, HIV infection is correlated to a significantly lower risk of developing multiple sclerosis (MS). The researchers analyzed a previous report by a team of Danish researchers whereby an HIV positive man with MS had his symptoms…

Data From Multiple Sclerosis Study of Trimesta For Disability, Cognitive Improvements in Women To Be Presented at ACTRIMS-ECTRIMS 2014

Synthetic Biologics, Inc., a biotechnology company developing novel drug candidates targeting specific pathogens that cause serious infections and diseases, announced that its latest data on Trimesta™, regarding cognitive and disability measures in women suffering from multiple sclerosis (MS), will be presented at the 2014 Joint Americas and European Committees…

Novartis And Tictrac Raise Awareness For MS With Health Tracking Challenge

Pharmaceutical company Novartis and health tracking and analytics platform Tictrac recently partnered up to support World Multiple Sclerosis Day and raise awareness for this disease by launching the campaign The 7-Day Challenge to Live Like You. The challenge, one of the first integrations of emerging technological trends by a pharmaceutical…

Committee for Medicinal Products for Human Use Adopts Positive Opinion For Plegridy As a Treatment for MS In The European Union

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency recently offered a positive opinion for the marketing authorization of Biogen Idec’s Plegridy therapy, a pegylated interferon administered subcutaneously for adults with relapsing-remitting multiple sclerosis (RRMS). The positive opinion will now be sent to the European Commission, which grants…

Combined Multiple Sclerosis Therapy Using Copaxone Relieves RRMS Symptoms In Study

Although the biological activity by which Copaxone (glatiramer) exerts its effects i multiple sclerosis (MS) patients is not fully understood, it is believed it can block the induction of autoimmune encephalomyelitis as observed in recent experiments with mice.  Research in animals and in vitro systems suggest that glatiramer acetate-specific suppressor…

New Report Cautions Marijuana As Treatment For MS

Marijuana has been approved for medicinal purposes in a number of U.S. states, however it still remains a much debated issue according to the American Academy of Neurology.  New information has been released by ANN Annual Meeting in Philadelphia, PA.  This represents the largest gathering of neurologists globally. According…